Human and Mammalian Cytogenetics
Human and Mammalian Cytogenetics

Author: T. C. Hsu

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 210

ISBN-13: 1461261597

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The history of science is mostly written retrospec tively, a generation or two after the actual events being discussed. Science historians are now analyzing and evaluating the origins of evolutionary and genetical theory in the nineteenth century and a sort of "Darwin industry" seems to have grown up. A history of mammalian cytogenetics by one of the main participants is, hence, a very welcome change, since it has a vividness, an immediacy and a personal flavor which these scholarly tomes and the official biog raphies of scientists mostly lack. The life of the author, Chinese-born, T. C. Hsu, has been a romantic and color ful one, and he is himself a unique personality, so that his book is a very unusual blend of reminiscences, history of his special field (which has transformed human genetics) and wise comments on the mistakes made along the way. The best qualities of a very fine Chinese mind have contributed to Dr. Hsu's career, including this book. Those qualities (which seem to me especially Chinese) include a kind of transparent honesty, a very direct em pirical approach to problems and superb technical ability.

Mammalian Cytogenetics and Related Problems in Radiobiology
Mammalian Cytogenetics and Related Problems in Radiobiology

Author: C. Pavan

Publisher: Elsevier

Published: 2013-10-22

Total Pages: 448

ISBN-13: 1483185265

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Mammalian Cytogenetics and Related Problems in Radiobiology covers the proceedings of a symposium held in Sao Paulo and Rio de Janeiro, Brazil in October 1962. The book focuses on the processes, methodologies, and approaches involved in mammalian cytogenetics and radiobiology. The selection first offers information on the nutrition and metabolism of cultured mammalian cells, blood technique and human chromosomes, and DNA replication in human chromosomes. Discussions focus on replication of heterochromatin in the human male; difficulties involved in the study of DNA synthesis in human chromosomes; and perspectives for future research. The text then ponders on the progress in the utilization of cell culture techniques for studies in mammalian and human somatic cell genetics and modification of radiation effects in the Ehrlich ascites tumor by oxygen or sodium azide. The manuscript examines experimental studies on mammalian chromosome aberrations, chromosome breakage in vitro, and survival of human cells in tissue culture after irradiation with densely and sparsely ionizing radiation. The text then elaborates on the observations on the morphology and behavior of normal human chromosomes, human pachytene chromosomes, and abnormalities of autosomes. The selection is a vital reference for readers interested in mammalian cytogenetics and radiobiology.

Comparative Mammalian Cytogenetics
Comparative Mammalian Cytogenetics

Author: Kurt Bernischke

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 494

ISBN-13: 3642859437

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Ten years ago a symposium on Cytotaxonomy 'was held in London (Proc. Linn. Soc. Lond. 169:110, 1958) in which a first attempt was made to bring together various disciplines to discuss advances of mammalian cytogenetics and to put them into proper context with the sciences of evolution and taxonomy. The introductory remarks by \V. B. Turrill to that symposium, essentially an admonishment to be tolerant of the short comings of our respective disciplines, would be a most appropriate begin ning to this conference as ,,'ell. However, the meeting held at Hanover was conceived more along the lines of remarks made by R. B. Seymour Se,,'ell in his presidential address to the same society: "It has been said that scientists in this search for truth are nowadays too much concerned with the accumulation of facts, and make too little use of their imagina tion in their attempts to explain such facts as they have accumulated. " (In "The continental drift theory and the distribution of the Copepoda," ibid. 166:149, 1956. ) \\Tith this as a background, two years ago we held the first of a series of loosely-structured conferences on reproductive failure in the relaxing atmosphere of this small New England college community. The manu scripts of that meeting have been published (Comparative Aspects of Re productive Failure, Springer-Verlag New York Inc. , 1967).

Comparative Mammalian Cytogenetics
Comparative Mammalian Cytogenetics

Author: Kurt Bernischke

Publisher: Springer

Published: 1969

Total Pages: 473

ISBN-13: 9783540044420

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Ten years ago a symposium on Cytotaxonomy 'was held in London (Proc. Linn. Soc. Lond. 169:110, 1958) in which a first attempt was made to bring together various disciplines to discuss advances of mammalian cytogenetics and to put them into proper context with the sciences of evolution and taxonomy. The introductory remarks by \V. B. Turrill to that symposium, essentially an admonishment to be tolerant of the short comings of our respective disciplines, would be a most appropriate begin ning to this conference as ,,'ell. However, the meeting held at Hanover was conceived more along the lines of remarks made by R. B. Seymour Se,,'ell in his presidential address to the same society: "It has been said that scientists in this search for truth are nowadays too much concerned with the accumulation of facts, and make too little use of their imagina tion in their attempts to explain such facts as they have accumulated. " (In "The continental drift theory and the distribution of the Copepoda," ibid. 166:149, 1956. ) \\Tith this as a background, two years ago we held the first of a series of loosely-structured conferences on reproductive failure in the relaxing atmosphere of this small New England college community. The manu scripts of that meeting have been published (Comparative Aspects of Re productive Failure, Springer-Verlag New York Inc. , 1967).

Chromosomes Today
Chromosomes Today

Author: N. Henriquez-Gil

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 399

ISBN-13: 9400915373

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Chromosomes Today Volume 12 records the plenary proceedings of the 12th triennial International Chromosone Conference, presenting an overview of the current concerns in the developing studies of animal, plant and human cytogenetics. As well as giving an accurate historical record of the achievements in chromosome studies, this important series points the way forword, emphasizing the areas in which new developments will take place. Volume 12 explores the complete integration of molecular biology and cytogenetics, evaluating the concensus of the world's cytogeneticists concerning the nature and activities of the chromosome.It reinforces our view of the chromosome as the genetic organelle whose structure, behaviour and modification underlie our modern concept ofeukaryote genetics.

Human Interphase Chromosomes
Human Interphase Chromosomes

Author: Ivan Iourov

Publisher: Springer Nature

Published: 2021-01-29

Total Pages: 184

ISBN-13: 303062532X

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This second edition focuses on the study of human interphase chromosomes and its relation to health and disease. Orchestrated organization and behavior of the human genome in interphase nuclei at chromosomal level has been repeatedly shown to play a significant role in almost all basic biological processes involved in the processing and inheritance of genetic information within and between species. Accordingly, post-genomic bioscience appeals to basic and applied studies of interphase nuclei genetics and genomics with special attention to interphase chromosome behavior in health and disease. Additionally, elucidating the role of interphase chromosome behavior during development, chromosome/DNA replication, DNA reparation opens new horizons for basic and applied bioscience Studies of interphase nuclei have an appreciable impact on different areas of biomedical sciences such as cell biology, neurobiology, cancer research, developmental biology, epigenetics, cytogenetics, and medical genetics, as a whole. Moreover, development of innovative and emergent technologies to analyze interphase nuclei are closely associated with application of these techniques in diagnostic and research practices to solve reproductive problems (including infertility and spontaneous abortions), to investigate congenital malformations (including those produced by aneuploidy and other chromosome abnormalities); genetic diseases (including cardiac, immune, neurological and psychiatric diseases), and cancer. This second edition serves as a source of updated valuable information and promising ideas for a wide audience of professionals in biomedicine including researchers, scientists, and healthcare professionals in human genetics, cytogenetics, and developmental biology.

Chromosome 12 Aberrations in Human Solid Tumors
Chromosome 12 Aberrations in Human Solid Tumors

Author: Jörn Bullerdiek

Publisher: Springer Science & Business Media

Published: 2013-04-17

Total Pages: 201

ISBN-13: 3662062550

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Researchers involved in the cytogenetics and molecular genetics of human tumors will welcome this comprehensive overview of the type of aberrations that chromosome 12 presents in human solid tumors. The authors study the implications for a cytogenetic subtyping of the tumors involved and strategies for identifying the molecular changes which underlie the karyotypic alterations. The aberrations of chromosome 12 which the book deals with are very frequent chromosomal alterations in human tumors occuring in frequent benign mesenchymal tumors, such as uterine leiomyomas and lipomas, and in tumors of epithelial origin, such as pleomorphic adenomas of the salivary glands.