Lyme Disease and Relapsing Fever Spirochetes

Lyme Disease and Relapsing Fever Spirochetes

Author: Justin D Radolf

Publisher:

Published: 2021

Total Pages: 770

ISBN-13: 9781913652616

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Lyme disease (Lyme borreliosis) is the most prevalent vector-borne illness in the United States and Europe and a growing threat to global health. In addition Lyme disease is considered a model system of emerging infectious diseases. The book Borrelia: Molecular Biology, Host Interaction and Pathogenesis published in 2010 was the first state-of-the-art reference work covering the myriad, interlaced facets of the enzootic disorders caused by pathogenic Borrelia. This current volume, by the same editors, builds on the previous work and contains a vast amount of new information, a wider scope, and increased coverage of genomics, genetics, evolutionary biology, vector biology, physiology, pathogenicity, immune response, and immune evasion. Written by renowned scientists who have made seminal contributions to the field, this book contains an expansive treatment of the options to track live spirochetes and evaluate gene expression in ticks and mice, provides insights into the workings of the flagellar motor, presents up-to-date research on the modulation of gene expression, and reviews recent studies on the Lyme disease spirochete's networks of regulatory pathways. The volume highlights and describes in detail the tremendous advances in understanding of the Borrelia genus at the molecular and cellular levels as well as the pathogenesis of Lyme disease and relapsing fever. This comprehensive volume is indispensable for anyone involved in Borrelia and Lyme disease research and is highly recommended for microbiologists, immunologists, and physicians with an interest in spirochetes, vector-borne illness, or emerging infectious diseases. The book is a recommended reference volume for all microbiology libraries.


Biology of Ticks Volume 1

Biology of Ticks Volume 1

Author: Daniel E. Sonenshine

Publisher: Oxford University Press

Published: 2013-12

Total Pages: 557

ISBN-13: 019974405X

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Spanning two volumes, this is the most comprehensive work on tick biology and tick-borne diseases.


Immunological Methods in Microbiology

Immunological Methods in Microbiology

Author:

Publisher: Academic Press

Published: 2020-04-29

Total Pages: 414

ISBN-13: 0128208112

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Immunological Methods in Microbiology, Volume 47 in the Methods in Microbiology series, highlights new advances in the field, with this new volume presenting interesting chapters on Immunological Techniques in the Clinical laboratory, Immunologic Diagnosis of HIV and Opportunistic Infections, Combining Antigen Detection and Serology for the Diagnosis of Selected Infectious Diseases, Immunologic Detection of Lyme Disease and Related Borrelioses, Immunodetection of Bacteria Causing Brucellosis, Immunological Diagnostic Techniques Used to Identify and Type Pasteurella, Immunological Tests for Diarrhea caused by Diarrheagenic Escherichia coli Targeting Their Main Virulence Factors, and much more.


Conquering Lyme Disease

Conquering Lyme Disease

Author: Brian A. Fallon

Publisher: Columbia University Press

Published: 2017-12-12

Total Pages: 608

ISBN-13: 0231545185

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Lyme disease is the most common tick-borne illness in the United States, with more than 300,000 cases diagnosed each year. However, doctors are deeply divided on how to diagnose and treat it, giving rise to the controversy known as the “Lyme Wars.” Firmly entrenched camps have emerged, causing physicians, patient communities, and insurance providers to be pitted against one another in a struggle to define Lyme disease and its clinical challenges. Health care providers may not be aware of its diverse manifestations or the limitations of diagnostic tests. Meanwhile, patients have felt dismissed by their doctors and confused by the conflicting opinions and dubious self-help information found online. In this authoritative book, the Columbia University Medical Center physicians Brian A. Fallon and Jennifer Sotsky explain that, despite the vexing “Lyme Wars,” there is cause for both doctors and patients to be optimistic. The past decade’s advances in precision medicine and biotechnology are reshaping our understanding of Lyme disease and accelerating the discovery of new tools to diagnose and treat it, such that the great divide previously separating medical communities is now being bridged. Drawing on both extensive clinical experience and cutting-edge research, Fallon, Sotsky, and their colleagues present these paradigm-shifting breakthroughs in language accessible to both sides. They clearly explain the immunologic, infectious, and neurologic basis of chronic symptoms, the cognitive and psychological impact of the disease, as well as current and emerging diagnostic tests, treatments, and prevention strategies. Written for the educated patient and health care provider seeking to learn more, Conquering Lyme Disease gives an up-to-the-minute overview of the science that is transforming the way we address this complex illness. It argues forcefully that the expanding plague of Lyme and other tick-borne diseases can be confronted successfully and may soon even be reversed.


Tick-borne Diseases of Humans

Tick-borne Diseases of Humans

Author: Jesse L. Goodman

Publisher:

Published: 2005

Total Pages: 442

ISBN-13:

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Comprehensive information on the biology, ecology, and clinical aspects of these diseases. Features in-depth profiles of specific diseases, including information on disease history, biology, epidemiology, ecology, transmission, clinical manifestations, diagnosis, treatment and prevention.


Environmental Aspects of Zoonotic Diseases

Environmental Aspects of Zoonotic Diseases

Author: Robert Armon

Publisher: IWA Publishing

Published: 2012-01-31

Total Pages: 517

ISBN-13: 184339085X

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Environmental Aspects of Zoonotic Diseases provides a definitive description, commentary and research needs of environmental aspects related to zoonotic diseases. There are many interrelated connections between the environment and zoonotic diseases such as: water, soil, air and agriculture. The book presents investigations of these connections, with specific reference to environmental processes such as: deforestation, floods, draughts, irrigation practices, soil transfer and their impact on bacterial, viral, fungal, and parasitological spread. Environmental aspects such as climate (tropical, sub-tropical, temperate, arid and semi-arid), developed and undeveloped countries, animal (domestic and wild) traffic animal border crossing, commercial animal trade, transportation, as well geography and weather on zoonosis, are also discussed and relevant scientific data is condensed and organized in order to give a better picture of interrelationship between the environment and current spread of zoonotic diseases. Altogether, the book presents a remarkable and a vast amount of potential future research directions based on the link: environment-vectors-pathogens-humans. The most up-to-date source of information on this increasingly important cross-disciplinary subject, Environmental Aspects of Zoonotic Diseases will be invaluable for environmentalists, veterinarians, medical staff, environmental engineers, government agencies and consultants working in this field. Authors: Prof. Robert Armon, Technion (Israel Institute of Technology), Haifa, Israel, Dr. Uta Cheruti, Technion (Israel Institute of Technology), Haifa, Israel


Molecular Biology of Spirochetes

Molecular Biology of Spirochetes

Author: Felipe C. Cabello

Publisher:

Published: 1912

Total Pages: 86

ISBN-13:

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Diseases produced by spirochetes, including Lyme borreliosis, syphilis and leptospirosis, are on the rise worldwide. This volume focuses on a series of state-of-the-art presentations of the research taking place in the laboratories of the contributors, and serves as an introduction to those individuals entering in the field of spirochete research.