NOW AT YOUR FINGERTIPS: Every performance test for completing a home energy audit. If you're a professional in today's fast-evolving industry of high performance construction and retrofits, then you've probably found yourself wondering a few things: Who can show me how to run that test? How do I get the most out of the equipment I own? Why do the tests work, and how do I explain them? What quality control methods should I use? Which tools will make my job faster and easier? With this guide, experienced and new diagnosticians alike will get step-by-step details on advanced testing, complete with best practices, important concepts and pitfalls, ways to present data to the client, Step-By-Step photographs, and time-saving tips, plus quiz questions for each diagnostic!
Praise for the First Edition " . . . the book is a valuable addition to the literature in the field, serving as a much-needed guide for both clinicians and advanced students."—Zentralblatt MATH A new edition of the cutting-edge guide to diagnostic tests in medical research In recent years, a considerable amount of research has focused on evolving methods for designing and analyzing diagnostic accuracy studies. Statistical Methods in Diagnostic Medicine, Second Edition continues to provide a comprehensive approach to the topic, guiding readers through the necessary practices for understanding these studies and generalizing the results to patient populations. Following a basic introduction to measuring test accuracy and study design, the authors successfully define various measures of diagnostic accuracy, describe strategies for designing diagnostic accuracy studies, and present key statistical methods for estimating and comparing test accuracy. Topics new to the Second Edition include: Methods for tests designed to detect and locate lesions Recommendations for covariate-adjustment Methods for estimating and comparing predictive values and sample size calculations Correcting techniques for verification and imperfect standard biases Sample size calculation for multiple reader studies when pilot data are available Updated meta-analysis methods, now incorporating random effects Three case studies thoroughly showcase some of the questions and statistical issues that arise in diagnostic medicine, with all associated data provided in detailed appendices. A related web site features Fortran, SAS®, and R software packages so that readers can conduct their own analyses. Statistical Methods in Diagnostic Medicine, Second Edition is an excellent supplement for biostatistics courses at the graduate level. It also serves as a valuable reference for clinicians and researchers working in the fields of medicine, epidemiology, and biostatistics.
Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing, Second Edition assembles a group of experts to discuss the molecular basis and mechanisms of major human diseases and disease processes and how the molecular features of disease can be harnessed to develop practical molecular tests for disease detection, diagnosis and prognosis. The book explains how molecular tests are utilized in the treatment of patients in personalized medicine, highlights new technologies and approaches of applied molecular pathology, and discusses how this discovery-based research yields new and useful biomarkers and tests. As it is essential to stay up-to-date on new molecular diagnostics in this changing field, this book covers critically important areas in the practice of personalized medicine and reflects our understanding of the pathology, pathogenesis and pathophysiology of human disease. - Includes new material on mass spectrometry for infectious diseases, microbiome, homology-directed repair for PARPi, whole genome sequencing for constitutional testing, and much more - Provides insights on the value of the molecular test in comparison to traditional methods, which include speed, precision, sensitivity and clinical impacts for the patient - Focuses on the menu of molecular diagnostic tests available in modern molecular pathology or clinical laboratories that can be applied to disease detection, diagnosis and classification in the clinical workup of a patient - Explains how molecular tests are utilized to guide the treatment of patients in personalized medicine (guided therapies) and for the prognostication of disease
Getting the right diagnosis is a key aspect of health care - it provides an explanation of a patient's health problem and informs subsequent health care decisions. The diagnostic process is a complex, collaborative activity that involves clinical reasoning and information gathering to determine a patient's health problem. According to Improving Diagnosis in Health Care, diagnostic errors-inaccurate or delayed diagnoses-persist throughout all settings of care and continue to harm an unacceptable number of patients. It is likely that most people will experience at least one diagnostic error in their lifetime, sometimes with devastating consequences. Diagnostic errors may cause harm to patients by preventing or delaying appropriate treatment, providing unnecessary or harmful treatment, or resulting in psychological or financial repercussions. The committee concluded that improving the diagnostic process is not only possible, but also represents a moral, professional, and public health imperative. Improving Diagnosis in Health Care, a continuation of the landmark Institute of Medicine reports To Err Is Human (2000) and Crossing the Quality Chasm (2001), finds that diagnosis-and, in particular, the occurrence of diagnostic errorsâ€"has been largely unappreciated in efforts to improve the quality and safety of health care. Without a dedicated focus on improving diagnosis, diagnostic errors will likely worsen as the delivery of health care and the diagnostic process continue to increase in complexity. Just as the diagnostic process is a collaborative activity, improving diagnosis will require collaboration and a widespread commitment to change among health care professionals, health care organizations, patients and their families, researchers, and policy makers. The recommendations of Improving Diagnosis in Health Care contribute to the growing momentum for change in this crucial area of health care quality and safety.
The essential guide to more than 450 of the most commonly performed diagnostic tests – updated with the latest molecular, genetic, and microbiological tests A Doody's Core Title for 2019! Guide to Diagnostic Tests, Seventh Edition is a concise guide to the selection and interpretation of more than 450 of the laboratory and microbiology tests most relevant to the general practice of medicine. This on-the-spot clinical companion also includes coverage of diagnostic imaging, electrocardiology, echocardiography, and the use of tests in differential diagnosis. Features: • Covers areas of internal medicine, pediatrics, surgery, neurology, and obstetrics and gynecology • Over 25 new or substantially revised laboratory tests • New and updated coverage of emerging and re-emerging pathogens and infectious agents,including the Zika and Ebola viruses • Updated material on molecular and genetic tests, including pharmacogenetics tests • An entire section of diagnostic algorithms • Full literature citations with PubMed identification (PMID) numbers included for each reference • Details costs and risks of various procedures and tests • Full section on electrocardiography and echocardiography If you’ve been looking for an authoritative, up-to-date, and easy-to-carry guide to the latest diagnostic testing procedures, your search ends here.
Up to date and easy to navigate, Fischbach’s A Manual of Laboratory and Diagnostic Tests, 11th Edition, details an extensive array of laboratory and diagnostic tests to prepare nurses and health professionals to deliver safe, effective, informed patient care. This proven manual is organized the way nurses think — by specimen, function, and test type— and provides current, comprehensive, step-by-step guidance on correct procedures, tips for accurate interpretation, and expert information on patient preparation and aftercare.
In this issue of Clinics in Laboratory Medicine, guest editors Drs. Jennifer Dien Bard and Esther Babady bring their considerable expertise to the topic of Diagnostics Stewardship in Molecular Microbiology: From At-Home Testing to Next Generation Sequencing. Molecular testing for infectious diseases diagnostics is quickly expanding beyond clinical microbiology laboratories, while higher complexity tests based on next generation sequencing are now available for infectious diseases diagnosis. Diagnostic stewardship, led by microbiology experts in collaboration with clinicians and other healthcare workers, is critical in ensuring responsible and judicious use of these tests. In this issue, top experts in the field address practical challenges and provide guidance for diagnostic stewardship of molecular infectious disease diagnostics tests, from point-of-care to next generation sequencing. - Contains 10 relevant, practice-oriented topics including taking center stage: clinical laboratory leading diagnostic stewardship efforts; mapping out when and on whom high-dollar NGS tests should be ordered; working with LIS to maximize ordering and reporting of molecular microbiology results; present and future non-culture-based diagnostics: what are the potentials and considerations as it relates to stewardship and the role of the clinical microbiologist?; and more. - Provides in-depth clinical reviews on diagnostics stewardship in molecular microbiology, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
Presenting the latest molecular diagnostic techniques in one comprehensive volume The molecular diagnostics landscape has changed dramatically since the last edition of Molecular Microbiology: Diagnostic Principles and Practice in 2011. With the spread of molecular testing and the development of new technologies and their opportunities, laboratory professionals and physicians more than ever need a resource to help them navigate this rapidly evolving field. Editors David Persing and Fred Tenover have brought together a team of experienced researchers and diagnosticians to update this third edition comprehensively, to present the latest developments in molecular diagnostics in the support of clinical care and of basic and clinical research, including next-generation sequencing and whole-genome analysis. These updates are provided in an easy-to-read format and supported by a broad range of practical advice, such as determining the appropriate type and quantity of a specimen, releasing and concentrating the targets, and eliminating inhibitors. Molecular Microbiology: Diagnostic Principles and Practice Presents the latest basic scientific theory underlying molecular diagnostics Offers tested and proven applications of molecular diagnostics for the diagnosis of infectious diseases, including point-of-care testing Illustrates and summarizes key concepts and techniques with detailed figures and tables Discusses emerging technologies, including the use of molecular typing methods for real-time tracking of infectious outbreaks and antibiotic resistance Advises on the latest quality control and quality assurance measures Explores the increasing opportunities and capabilities of information technology Molecular Microbiology: Diagnostic Principles and Practice is a textbook for molecular diagnostics courses that can also be used by anyone involved with diagnostic test selection and interpretation. It is also a useful reference for laboratories and as a continuing education resource for physicians. If you are looking for online access to the latest clinical microbiology content, please visit www.wiley.com/learn/clinmicronow.
Flow cytometry continually amazes scientists with its ever-expanding utility. Advances in flow cytometry have opened new directions in theoretical science, clinical diagnosis, and medical practice. The new edition of Flow Cytometry: First Principles provides a thorough update of this now classic text, reflecting innovations in the field while outlining the fundamental elements of instrumentation, sample preparation, and data analysis. Flow Cytometry: First Principles, Second Edition explains the basic principles of flow cytometry, surveying its primary scientific and clinical applications and highlighting state-of-the-art techniques at the frontiers of research. This edition contains extensive revisions of all chapters, including new discussions on fluorochrome and laser options for multicolor analysis, an additionalsection on apoptosis in the chapter on DNA, and new chapters onintracellular protein staining and cell sorting, including high-speed sorting and alternative sorting methods, as well as traditional technology. This essential resource: Assumes no prior knowledge of flow cytometry Progresses with an informal, engaging lecture style from simpleto more complex concepts Offers a clear introduction to new vocabulary, principles of instrumentation, and strategies for data analysis Emphasizes the theory relevant to all flow cytometry, with examples from a variety of clinical and scientific fields Flow Cytometry: First Principles, Second Edition provides scientists, clinicians, technologists, and students with the knowledge necessary for beginning the practice of flow cytometry and for understanding related literature.
A quick reference guide to the selection and interpretation of more than 450 commonly used diagnostic tests COVERS: Basic principles of diagnostic testing, common blood, urine and cerebrospinal fluid laboratory tests, therapeutic drug monitoring, microbiologic test selection and interpretation and diagnostic imaging tests by body system , electrocardiography, and differential diagnosis tables & algorithms Tests used in internal medicine, pediatrics, surgery, neurology and obstetrics and gynecology INCLUDES: Costs and risks of diagnostic tests Evidence-based information Diseases associated with abnormal test results, including test sensitivities Full literature citations with PubMed (PMID) numbers included for each reference More than 24 NEW clinical laboratory test entries, 6 NEW differential diagnosis tables 5 NEW diagnostic algorithms NEW sections on point-of-care testing, provider-performed microscopy, pharmacogenetic testing, and diagnostic echocardiography
