Heart Tantrums and Brain Tumours
Heart Tantrums and Brain Tumours

Author: Aisha Sarwari

Publisher: Oxford University Press

Published: 2023-08-10

Total Pages: 498

ISBN-13: 178738893X

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When Aisha Sarwari left her childhood home in Uganda for America as a young woman, she set out to create her own identity and story. The daughter of Pakistani and Indian migrants, she had never lived in South Asia. Raised to be a 'good Muslim girl', she struggled to reconcile these culturalexpectations with her desire for equality and acceptance.After she met Yasser, a Pakistani law student, they returned to their ancestral country and married. Little did they know that a brain tumor would become an almost lethal third wheel in their relationship. The cancer gnawed at Yasser's personality, provoking aggressive outbursts. The illnessexplained Yasser's violence, Aisha told herself; but at what point did it become the excuse? She began to see their marriage within a bigger picture--of women's place in an oppressive society, and of the tug between feminist principles and personal happiness.Between Africa, the USA and Pakistan, this is a unique story of abuse and trauma, identity and belonging, misogyny and motherhood, patriarchy and power. With searing honesty and political passion, Heart Tantrums and Brain Tumors reveals one woman's battle to redefine the rules--by fighting for, andsometimes with, the man she loved.

Heart Tantrums
Heart Tantrums

Author: Aisha Sarwari

Publisher: Penguin Random House India Private Limited

Published: 2023-08-28

Total Pages: 421

ISBN-13: 9357082514

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In order to be able to survive, Aisha Sarwari was told, love and devoted acts of service will always light the way. These however, become the very reason of her complete unravelling. In this large and messy voice of a memoir, Heart Tantrums artfully describes the scatter of catastrophic losses-the loss of her father in early adolescence; leaving behind her family home in East Africa; and trying to fit into a completely different culture in Lahore after marriage. In 2017, when Aisha first held her husband Yasser Latif Hamdani's brain MRI against the light, she began to also lose the man she loved to a personality-altering brain tumour. Oscillating between being a good woman and a bad woman, Aisha has been adamant that the hard knocks of life would not define her. But even self-respect comes at a high price. The internal life of mental health chaos is like the very disease itself-degenerative. The book rejects the idea that love and domestic servitude saves the day. Pakistan, she never thought, could become like living in a state of self-exile for the couple that married for country-Aisha Sarwari, a proud Pakistani feminist and career professional, and Yasser Latif Hamdani, a human rights lawyer turned internationally acclaimed biographer of Pakistan's founding father, M.A. Jinnah. Often, they both failed to play for the team, but their fight for belonging was sometimes punctuated by the warmth of parenting and the joy of extraordinary friendships. This book is a prayer on a page, with this immigrant girl finding her way in the dark through a raw and magnificently well-told story of grief, hybrid identity, immigration woes, systemic family oppression, caregiver fatigue and, of course, what every good literature tries hard to hack-the terror of oblivion.

Role of BH3-only Proteins in ER Stress and Heart Failure
Role of BH3-only Proteins in ER Stress and Heart Failure

Author: Jason Andrew Glab

Publisher: Nomadicindian

Published: 2023-04-16

Total Pages: 0

ISBN-13: 9781805262268

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Cells may die by a number of mechanisms, whether it be to the detriment or benefit of the organism. This can be external to the control of the cell, or initiated and executed by the cell itself, in response to various stimuli. Programmed cell death, when the cell regulates its own demise in response to specific stimuli, may occur through processes such as apoptosis, necroptosis and pyroptosis (D'Arcy, 2019). The most commonly investigated form of programmed cell death to date is apoptosis, which was first described in 1972 (Kerr et al., 1972). Further advances have been made in the understanding of apoptosis since then, stemming from investigation of programmed cell death in C. elegans (Horvitz, 1999). Its evolutionary conservation as a mechanism of cell death across diverse species, ranging from the aforementioned nematodes to mammals, indicates the ironic importance of this process in the maintenance of life (Severin et al., 2008). Apoptosis is important in both health and disease, regulating embryonic development and displaying polarising roles in pathologies such as cancer and sepsis (Glab et al., 2017b). As such, apoptosis can be both harmful and beneficial to an organism. Additionally, unlike sporadic cell death mechanisms like necrosis, the orderly manner of apoptotic cell disassembly enables the process to go largely undetected by the immune system and avoid initiating inflammatory responses that may otherwise damage the surrounding tissue (Rock and Kono, 2008). Apoptosis can be initiated in response to a variety of stimuli, both intra- and extracellular in origin (Danial and Korsmeyer, 2004). These then activate one of two distinct pathways, ultimately converging on the death of the cell

Heart Tantrums and Brain Tumors
Heart Tantrums and Brain Tumors

Author: Aisha Sarwari

Publisher: Oxford University Press

Published: 2023-08-01

Total Pages: 513

ISBN-13: 1787389987

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When Aisha Sarwari moved to America as a young woman, she set out to create her own identity and story. Born in Uganda, she had never lived in South Asia, yet struggled to reconcile the cultural expectation to be a "good Muslim girl" with her desire for equality and acceptance. After she met Yasser, a Pakistani law student, they returned to their ancestral country and married. Little did they know that a brain tumor would become a near-lethal third wheel in their relationship. The cancer gnawed at Yasser's personality, provoking aggressive outbursts. Was the illness still the explanation for his violence, or had it become an excuse? Aisha began to see their marriage within a bigger picture--of an oppressive society, and of the tug between feminist principles and personal happiness. Between Africa, America and Pakistan, Heart Tantrums and Brain Tumors is a unique story of identity and belonging, misogyny and motherhood, patriarchy and partnership. Its searing honesty and political passion reveal one woman's battle to redefine the rules--by fighting for, and sometimes with, the man she loves.

Brain Tumors in Children
Brain Tumors in Children

Author: Amar Gajjar

Publisher: Springer

Published: 2018-09-29

Total Pages: 426

ISBN-13: 3319432052

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This book is a comprehensive and up-to-date compendium of all aspects of brain tumors in children. After introductory chapters on the epidemiology of brain tumors, the book will provide readers with state-of-the art chapters on the principals of radiation therapy, neurosurgery and neuroimaging. Subsequent chapters discuss the biology and treatment of specific types of brain tumors. The concluding chapters present critical information relevant to survivorship, neurocognitive and other late effects, and the global challenges to better diagnosis and treatment of brain tumors in children. This book is co-authored by experts in the treatment of pediatric brain tumors. All of the authors are internationally recognized authorities and they offer an evidence-based consensus on the biology and treatment of brain tumors. This handbook has far-reaching applicability to the clinical diagnosis and management of brain tumors in children and will prove valuable to specialists, generalists and trainees alike.

Magnesium in the Central Nervous System
Magnesium in the Central Nervous System

Author: Robert Vink

Publisher: University of Adelaide Press

Published: 2011

Total Pages: 354

ISBN-13: 0987073052

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The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

The Iceberg
The Iceberg

Author: Marion Coutts

Publisher: Open Road + Grove/Atlantic

Published: 2016-02-02

Total Pages: 249

ISBN-13: 0802190529

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“The work of an exceptional woman artist, writing from the inside about the things women have always done: nursing, nurturing, loving.” —The Guardian Winner of the Wellcome Book Prize, and finalist for every major nonfiction award in the UK, including the Samuel Johnson Prize and the Costa Biography Award, The Iceberg is artist and writer Marion Coutts’ astonishing memoir; an “adventure of being and dying” and a compelling, poetic meditation on family, love, and language. In 2008, Tom Lubbock, the chief art critic for The Independent was diagnosed with a brain tumor. The Iceberg is his wife, Marion Coutts’, fierce, exquisite account of the two years leading up to his death. In spare, breathtaking prose, Coutts conveys the intolerable and, alongside their two-year-old son Ev—whose language is developing as Tom’s is disappearing—Marion and Tom lovingly weather the storm together. In short bursts of exquisitely textured prose, The Iceberg becomes a singular work of art and an uplifting and universal story of endurance in the face of loss. “Dazzling, devastating . . . In her plain-spoken retelling of the commonplace human experience of illness and loss, Coutts achieves something truly extraordinary—she’s created one of the most haunting and achingly honest explorations of grief in recent memory.” —Los Angeles Times

Childhood Cancer Survivors
Childhood Cancer Survivors

Author: Nancy Keene

Publisher: Childhood Cancer Guides

Published: 2014-03-01

Total Pages: 481

ISBN-13: 1941089143

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More than 325,000 children, teens, and adults in the United States are survivors of childhood cancer. The surgery, radiation, chemotherapy, and stem cell transplants used to cure children can affect growing bodies and developing minds. If survivors know of these potential problems, they can take steps to identify, cope with, or treat them early if they do develop. The third edition of Childhood Cancer Survivors charts the territory for survivors by providing state-of-the-art information about: " Medical late effects from treatment " Emotional aspects of surviving cancer " Schedules for follow-up care " Challenges in the heath-care system " Lifestyle choices to maximize health " Discrimination in employment or insurance Woven throughout the text are stories from more than 100 survivors and parents. Authors Keene, Hobbie, and Ruccione are experts in the field of childhood cancer. Keene is the mother of a survivor of childhood leukemia and the author of several books including Childhood Leukemia, Childhood Cancer, Educating the Child with Cancer, and Chemo, Craziness & Comfort. Hobbie is Associate Director of the Cancer Survivorship Program at Children's Hospital of Philadelphia. Ruccione is Co-Director of the HOPE (Hematology-Oncology Psychosocial and Education) Program in the Children's Center for Cancer and Blood Diseases at Children's Hospital Los Angeles.

Stroke Syndromes, 3ed
Stroke Syndromes, 3ed

Author: Louis R. Caplan

Publisher: Cambridge University Press

Published: 2012-07-12

Total Pages: 633

ISBN-13: 1107018862

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A comprehensive survey of dysfunction due to stroke, this revised edition remains the definitive guide to stroke patterns and syndromes.

VP Menon
VP Menon

Author: Narayani Basu

Publisher: Simon and Schuster

Published: 2020-02-04

Total Pages: 675

ISBN-13: 9386797690

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With his initial plans for an independent India in tatters, the desperate viceroy, Lord Mountbatten, turned to his seniormost Indian civil servant, Vappala Pangunni Menon—or VP—giving him a single night to devise an alternative, coherent and workable plan for independence. Menon met his stringent deadline, presenting the Menon Plan, which would change the map of the world forever. Menon was unarguably the architect of the modern Indian state. Yet startlingly little is known about this bureaucrat, patriot and visionary. In this definitive biography, Menon’s great-granddaughter, Narayani Basu, rectifies this travesty. She takes us through the highs and lows of his career, from his determination to give women the right to vote; to his strategy, at once ruthless and subtle, to get the princely states to accede to India; to his decision to join forces with the Swatantra Party; to his final relegation to relative obscurity. Equally, the book candidly explores the man behind the public figure— his unconventional personal life and his private conflicts, which made him channel his energy into public service. Drawing from documents—scattered, unread and unresearched until now—and with unprecedented access to Menon’s papers and his taped off-the-record and explosively frank interviews—this remarkable biography of VP Menon not only covers the life and times of a man unjustly consigned to the footnotes of history but also changes our perception of how India, as we know it, came into being.