Environmental Toxicants

Environmental Toxicants

Author: Morton Lippmann

Publisher: John Wiley & Sons

Published: 2009-03-26

Total Pages: 1189

ISBN-13: 0470442883

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Provides the most current information and research available for performing risk assessments on exposed individuals and populations, giving guidance to public health authorities, primary care physicians, and industrial managers Reviews current knowledge on human exposure to selected chemical agents and physical factors in the ambient environment Updates and revises the previous edition, in light of current scientific literature and its significance to public health concerns Includes new chapters on: airline cabin exposures, arsenic, endocrine disruptors, and nanoparticles


Health Assessment Document for Diesel Engine Exhaust

Health Assessment Document for Diesel Engine Exhaust

Author: U. S. Environmental Agency

Publisher: CreateSpace

Published: 2015-01-06

Total Pages: 674

ISBN-13: 9781505957921

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This Health Assessment Document for Diesel Engine Exhaust (DE) represents EPA's first comprehensive review of the potential health effects from ambient exposure to exhaust from diesel engines. The assessment was developed to provide information about the potential for DE to pose environmental health hazards, information that would be useful in evaluating regulatory needs under provisions of the Clean Air Act. The assessment identifies and characterizes the potential human health hazards of DE (i.e, hazard assessment) and seeks to estimate the relationship between exposure and disease response for the key health effects (i.e., dose-response assessment). The diesel engine has been a vital workhorse in the United States, powering many of its large trucks, buses, and farm, railroad, marine, and construction equipment. Expectations are that diesel engine use in these areas will increase due to the superior performance characteristics of the engine. Diesel engine exhaust (DE), however, contains harmful pollutants in a complex mixture of gases and particulates. Human exposure to this exhaust comes from both highway uses (on-road) as well as non-road uses of the diesel engine. EPA started evaluating and regulating the gaseous emissions from the heavy-duty highway use of diesel engines in the 1970s and particle emissions in the 1980s. The reduction of harmful exhaust emissions has taken a large step forward because of standards issued in 2000 which will bring about very large reductions in exhaust emissions for model year 2007 heavy-duty engines used in trucks, buses, and other on-road uses. A draft of this assessment, along with the peer review comments of the Clean Air Scientific Advisory Committee, was part of the scientific basis for EPA's regulation of heavy-duty highway engines completed in December 2000. The information provided by this assessment was useful in developing EPA's understanding of the public health implications of exposure to DE and the public health benefits of taking regulatory action to control exhaust emissions. EPA anticipates developing similarly stringent regulations for other diesel engine uses, including those used in non-road applications.


Diesel and Gasoline Engine Exhausts and Some Nitroarenes

Diesel and Gasoline Engine Exhausts and Some Nitroarenes

Author: IARC Working Group on the Evaluation of Carcinogenic Risks to Humans

Publisher: IARC Monographs on the Evaluat

Published: 2015-06-04

Total Pages: 0

ISBN-13: 9789283213284

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This volume of the IARC Monographs provides evaluations of the carcinogenicity of diesel and gasoline engine exhausts, and of 10 nitroarenes found in diesel engine exhaust: 3,7-dinitrofluoranthene, 3,9-dinitrofluoranthene, 1,3-dinitropyrene, 1,6-dinitropyrene, 1,8-dinitropyrene, 6-nitrochrysene, 2-nitrofluorene, 1-nitropyrene, 4-nitropyrene, and 3-nitrobenzanthrone. Diesel engines are used for transport on and off roads (e.g. passenger cars, buses, trucks, trains, ships), for machinery in various industrial sectors (e.g. mining, construction), and for electricity generators, particularly in developing countries. Gasoline engines are used in cars and hand-held equipment (e.g. chainsaws). The emissions from such combustion engines comprise a complex and varying mixture of gases (e.g. carbon monoxide, nitrogen oxides), particles (e.g. PM10, PM2.5, ultrafine particles, elemental carbon, organic carbon, ash, sulfate, and metals), volatile organic compunds (e.g. benzene, formaldehyde) and semi-volatile organic compounds (e.g. polycyclic aromatic hydrocarbons) including oxygenated and nitrated derivatives of polycyclic aromatic hydrocarbons. Diesel and gasoline engines thus make a significant contribution to a broad range of air pollutants to which people are exposed in the general population as well as in different occupational settings. An IARC Monographs Working Group reviewed epidemiological evidence, animal bioassays, and mechanistic and other relevant data to reach conclusions as to the carcinogenic hazard to humans of environmental or occupational exposure to diesel and gasoline engine exhausts (including those associated with the mining, railroad, construction, and transportation industries) and to 10 selected nitroarenes. -- Back cover.


Control of Diesel Engine Exhaust Emissions in the Workplace

Control of Diesel Engine Exhaust Emissions in the Workplace

Author:

Publisher:

Published: 2008

Total Pages: 0

ISBN-13: 9780717663064

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Offers practical advice to employers and self-employed people on how to control exposure to diesel engine exhaust emissions (DEEEs) in the workplace to protect the health of employees and others who may be exposed. This title is suitable for managers, supervisors, employees, and health and safety professionals.


Air Pollution, the Automobile, and Public Health

Air Pollution, the Automobile, and Public Health

Author: Sponsored by The Health Effects Institute

Publisher: National Academies Press

Published: 1988-01-01

Total Pages: 703

ISBN-13: 0309037263

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"The combination of scientific and institutional integrity represented by this book is unusual. It should be a model for future endeavors to help quantify environmental risk as a basis for good decisionmaking." â€"William D. Ruckelshaus, from the foreword. This volume, prepared under the auspices of the Health Effects Institute, an independent research organization created and funded jointly by the Environmental Protection Agency and the automobile industry, brings together experts on atmospheric exposure and on the biological effects of toxic substances to examine what is knownâ€"and not knownâ€"about the human health risks of automotive emissions.


Controlled Human Inhalation-Exposure Studies at EPA

Controlled Human Inhalation-Exposure Studies at EPA

Author: National Academies of Sciences, Engineering, and Medicine

Publisher: National Academies Press

Published: 2017-04-10

Total Pages: 159

ISBN-13: 030945252X

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The U.S. Environmental Protection Agency (EPA) has a mission and regulatory responsibility to protect human health and the environment. EPA's pursuit of that goal includes a variety of research activities involving human subjects, such as epidemiologic studies and surveys. Those research activities also involve studies of individuals who volunteer to be exposed to air pollutants intentionally in controlled laboratory settings so that measurements can be made of transient and reversible biomarker or physiologic responses to those exposures that can indicate pathways of toxicity and mechanisms of air-pollution responses. The results of those controlled human inhalation exposure (CHIE) studies, also referred to as human clinical studies or human challenge studies, are used to inform policy decisions and help establish or revise standards to protect public health and improve air quality. Controlled Human Inhalation-Exposure Studies at EPA addresses scientific issues and provides guidance on the conduct of CHIE studies. This report assesses the utility of CHIE studies to inform and reduce uncertainties in setting air-pollution standards to protect public health and assess whether continuation of such studies is warranted. It also evaluates the potential health risks to test subjects who participated in recent studies of air pollutants at EPA's clinical research facility.