Hardware/Software Co-Design and Optimization for Cyberphysical Integration in Digital Microfluidic Biochips

Hardware/Software Co-Design and Optimization for Cyberphysical Integration in Digital Microfluidic Biochips

Author: Yan Luo

Publisher: Springer

Published: 2014-08-06

Total Pages: 208

ISBN-13: 3319090062

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This book describes a comprehensive framework for hardware/software co-design, optimization, and use of robust, low-cost, and cyberphysical digital microfluidic systems. Readers with a background in electronic design automation will find this book to be a valuable reference for leveraging conventional VLSI CAD techniques for emerging technologies, e.g., biochips or bioMEMS. Readers from the circuit/system design community will benefit from methods presented to extend design and testing techniques from microelectronics to mixed-technology microsystems. For readers from the microfluidics domain, this book presents a new design and development strategy for cyberphysical microfluidics-based biochips suitable for large-scale bioassay applications. • Takes a transformative, “cyberphysical” approach towards achieving closed-loop and sensor feedback-driven biochip operation under program control; • Presents a “physically-aware” system reconfiguration technique that uses sensor data at intermediate checkpoints to dynamically reconfigure biochips; • Enables readers to simplify the structure of biochips, while facilitating the “general-purpose” use of digital microfluidic biochips for a wider range of applications.


Advanced Logic Synthesis

Advanced Logic Synthesis

Author: André Inácio Reis

Publisher: Springer

Published: 2017-11-15

Total Pages: 236

ISBN-13: 3319672959

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This book provides a single-source reference to the state-of-the-art in logic synthesis. Readers will benefit from the authors’ expert perspectives on new technologies and logic synthesis, new data structures, big data and logic synthesis, and convergent logic synthesis. The authors describe techniques that will enable readers to take advantage of recent advances in big data techniques and frameworks in order to have better logic synthesis algorithms.


Micro-Electrode-Dot-Array Digital Microfluidic Biochips

Micro-Electrode-Dot-Array Digital Microfluidic Biochips

Author: Zipeng Li

Publisher: Springer

Published: 2018-12-14

Total Pages: 152

ISBN-13: 3030029646

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This book provides an insightful guide to the design, testing and optimization of micro-electrode-dot-array (MEDA) digital microfluidic biochips. The authors focus on the characteristics specific for MEDA biochips, e.g., real-time sensing and advanced microfluidic operations like lamination mixing and droplet shape morphing. Readers will be enabled to enhance the automated design and use of MEDA and to develop a set of solutions to facilitate the full exploitation of design complexities that are possible with standard CMOS fabrication techniques. The book provides the first set of design automation and test techniques for MEDA biochips. The methods described in this book have been validated using fabricated MEDA biochips in the laboratory. Readers will benefit from an in-depth look at the MEDA platform and how to combine microfluidics with software, e.g., applying biomolecular protocols to software-controlled and cyberphysical microfluidic biochips.


Computer-Aided Design of Microfluidic Very Large Scale Integration (mVLSI) Biochips

Computer-Aided Design of Microfluidic Very Large Scale Integration (mVLSI) Biochips

Author: Kai Hu

Publisher: Springer

Published: 2017-04-05

Total Pages: 151

ISBN-13: 331956255X

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This book provides a comprehensive overview of flow-based, microfluidic VLSI. The authors describe and solve in a comprehensive and holistic manner practical challenges such as control synthesis, wash optimization, design for testability, and diagnosis of modern flow-based microfluidic biochips. They introduce practical solutions, based on rigorous optimization and formal models. The technical contributions presented in this book will not only shorten the product development cycle, but also accelerate the adoption and further development of modern flow-based microfluidic biochips, by facilitating the full exploitation of design complexities that are possible with current fabrication techniques.


VLSI Design and Test

VLSI Design and Test

Author: Brajesh Kumar Kaushik

Publisher: Springer

Published: 2017-12-21

Total Pages: 820

ISBN-13: 9811074704

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This book constitutes the refereed proceedings of the 21st International Symposium on VLSI Design and Test, VDAT 2017, held in Roorkee, India, in June/July 2017. The 48 full papers presented together with 27 short papers were carefully reviewed and selected from 246 submissions. The papers were organized in topical sections named: digital design; analog/mixed signal; VLSI testing; devices and technology; VLSI architectures; emerging technologies and memory; system design; low power design and test; RF circuits; architecture and CAD; and design verification.


Applied Computing for Software and Smart Systems

Applied Computing for Software and Smart Systems

Author: Rituparna Chaki

Publisher: Springer Nature

Published: 2024-01-27

Total Pages: 232

ISBN-13: 9819977835

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This book features a collection of high-quality research papers presented at the 10th International Symposium on Applied Computing for Software and Smart systems (ACSS 2023), to be held during September 15–16, 2023, in Kolkata, India. The book presents innovative works by undergraduate, graduate students as well as Ph.D. scholars. The emphasis of the workshop is on software and smart systems and research outcomes on other relevant areas pertaining to advancement of computing.


Drug Delivery Devices and Therapeutic Systems

Drug Delivery Devices and Therapeutic Systems

Author: Eric Chappel

Publisher: Academic Press

Published: 2020-11-07

Total Pages: 680

ISBN-13: 0128198397

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Drug Delivery Devices and Therapeutic Systems examines the current technology and innovations moving drug delivery systems (DDS) forward. The book provides an overview on the therapeutic use of drug delivery devices, including design, applications, and a description of the design of each device. While other books focus on the therapy, the primary emphasis in this book is on current technologies for DDS applications, including microfluidics, nanotechnology, biodegradable hydrogel and microneedles, with a special emphasis on wearable DDS. As part of the Developments in Biomedical Engineering and Bioelectronics series, this book is written by experts in the field and informed with information directly from manufacturers. Pharmaceutical scientists, medical researchers, biomedical engineers and clinical professionals will find this an essential reference. - Provides essential information on the most recent drug delivery systems available - Explains current technology and its applications to drug delivery - Contains contributions from biomedical engineers, pharmaceutical scientists and manufacturers


Digital Microfluidic Biochips

Digital Microfluidic Biochips

Author: Krishnendu Chakrabarty

Publisher: CRC Press

Published: 2018-10-03

Total Pages: 228

ISBN-13: 1420008307

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Digital Microfluidic Biochips focuses on the automated design and production of microfluidic-based biochips for large-scale bioassays and safety-critical applications. Bridging areas of electronic design automation with microfluidic biochip research, the authors present a system-level design automation framework that addresses key issues in the design, analysis, and testing of digital microfluidic biochips. The book describes a new generation of microfluidic biochips with more complex designs that offer dynamic reconfigurability, system scalability, system integration, and defect tolerance. Part I describes a unified design methodology that targets design optimization under resource constraints. Part II investigates cost-effective testing techniques for digital microfluidic biochips that include test resource optimization and fault detection while running normal bioassays. Part III focuses on different reconfiguration-based defect tolerance techniques designed to increase the yield and dependability of digital microfluidic biochips. Expanding upon results from ongoing research on CAD for biochips at Duke University, this book presents new design methodologies that address some of the limitations in current full-custom design techniques. Digital Microfluidic Biochips is an essential resource for achieving the integration of microfluidic components in the next generation of system-on-chip and system-in-package designs.


Computer Organization and Design

Computer Organization and Design

Author: David A. Patterson

Publisher: Elsevier

Published: 2012

Total Pages: 920

ISBN-13: 0123747503

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Rev. ed. of: Computer organization and design / John L. Hennessy, David A. Patterson. 1998.


Computer Organization and Design

Computer Organization and Design

Author: David A. Patterson

Publisher: Elsevier

Published: 2004-08-07

Total Pages: 690

ISBN-13: 0080502571

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This best selling text on computer organization has been thoroughly updated to reflect the newest technologies. Examples highlight the latest processor designs, benchmarking standards, languages and tools. As with previous editions, a MIPs processor is the core used to present the fundamentals of hardware technologies at work in a computer system. The book presents an entire MIPS instruction set—instruction by instruction—the fundamentals of assembly language, computer arithmetic, pipelining, memory hierarchies and I/O. A new aspect of the third edition is the explicit connection between program performance and CPU performance. The authors show how hardware and software components--such as the specific algorithm, programming language, compiler, ISA and processor implementation--impact program performance. Throughout the book a new feature focusing on program performance describes how to search for bottlenecks and improve performance in various parts of the system. The book digs deeper into the hardware/software interface, presenting a complete view of the function of the programming language and compiler--crucial for understanding computer organization. A CD provides a toolkit of simulators and compilers along with tutorials for using them. For instructor resources click on the grey "companion site" button found on the right side of this page.This new edition represents a major revision. New to this edition:* Entire Text has been updated to reflect new technology* 70% new exercises.* Includes a CD loaded with software, projects and exercises to support courses using a number of tools * A new interior design presents defined terms in the margin for quick reference * A new feature, "Understanding Program Performance" focuses on performance from the programmer's perspective * Two sets of exercises and solutions, "For More Practice" and "In More Depth," are included on the CD * "Check Yourself" questions help students check their understanding of major concepts * "Computers In the Real World" feature illustrates the diversity of uses for information technology *More detail below...