Handbook of Neuroemergency Clinical Trials
Handbook of Neuroemergency Clinical Trials

Author: Brett E. Skolnick

Publisher: Academic Press

Published: 2017-11-01

Total Pages: 600

ISBN-13: 9780128040645

DOWNLOAD EBOOK

Handbook of Neuroemergency Clinical Trials, 2e focuswa on the "state of the practice" of clinical trials in acute neuroscience populations, or what have been called "neuroemergencies." Neuroemergencies are complex life-threatening diseases and disorders, often with devastating consequences including death or disability. The overall costs are staggering in terms of annual incidence and costs associated with treatment and survival from acute neurological emergencies. Yet, despite their significance as public health issues, there are few drugs and devices available for definitive treatment The book focuses on novel therapies and the unique challenges their intended targets pose for the design and analysis of clinical trials. This volume provides neurologists, neuroscientists, and drug developers with a more complete understanding of the scientific and medical issues of relevance in designing and initiating clinical development plans for novel drugs intended for acute neuroscience populations. The editors provide the best understanding of the pitfalls associated with acute CNS drug development and the best information available regarding how to approach and solve the issues that have plagued drug development. Comprehensive overview on clinical trials and drug development challenges in acute neuroscience populations Provides neurologists, neuroscientists, and drug developers with a complete understanding of scientific and medical issues related to designing clinical trials Edited by leaders in the field who have designed and managed over 50 neuroemergency clinical trials

Handbook of Neuroemergency Clinical Trials
Handbook of Neuroemergency Clinical Trials

Author: Brett E. Skolnick

Publisher: Academic Press

Published: 2017-11-13

Total Pages: 408

ISBN-13: 0128041013

DOWNLOAD EBOOK

Handbook of Neuroemergency Clinical Trials, Second Edition, focuses on the practice of clinical trials in acute neuroscience populations, or what have been called neuroemergencies. Neuroemergencies are complex, life-threatening diseases and disorders, often with devastating consequences, including death or disability. The overall costs are staggering in terms of annual incidence and costs associated with treatment and survival, yet despite their significance as public health issues, there are few drugs and devices available for definitive treatment. The book focuses on novel therapies and the unique challenges their intended targets pose for the design and analysis of clinical trials. This volume provides neurologists, neuroscientists, and drug developers with a more complete understanding of the scientific and medical issues of relevance in designing and initiating clinical development plans for novel drugs intended for acute neuroscience populations. The editors provide the best understanding of the pitfalls associated with acute CNS drug development and the best information on how to approach and solve issues that have plagued drug development. Presents a comprehensive overview on clinical trials and drug development challenges in acute neuroscience populations Provides neurologists, neuroscientists and drug developers with a complete understanding of scientific and medical issues related to designing clinical trials Edited by leaders in the field who have designed and managed over 50 neuroemergency clinical trials

Handbook of Clinical Trials
Handbook of Clinical Trials

Author: P. Brouwers

Publisher: CRC Press

Published: 1991-01-01

Total Pages: 396

ISBN-13: 9789026510281

DOWNLOAD EBOOK

Behavior is an aspect of clinical trials that has been somewhat neglected, and the problems associated with behavioral assessment and control in clinical trials are complex. These contributions deal with the selection and application of assessment techniques in different patient populations, the scr

Traumatic Brain Injury, Part II
Traumatic Brain Injury, Part II

Author: Jordan Grafman

Publisher: Elsevier

Published: 2015-02-17

Total Pages: 0

ISBN-13: 9780444635211

DOWNLOAD EBOOK

The Handbook of Clinical Neurology volumes on Traumatic Brain Injury (TBI) provide the reader with an updated review of emerging approaches to TBI research, clinical management and patient rehabilitation. Chapters in Part II offer coverage of clinical sequelae and long-term outcome, brain plasticity and long-term risks, and clinical trials. Contemporary investigations on blast injury and chronic traumatic encephalopathy are presented, making this state-of-the-art volume a must have for clinicians and researchers concerned with the clinical management, or investigation, of TBI.

Clinical Trials in Neurology
Clinical Trials in Neurology

Author: Felipe Fregni

Publisher: Humana

Published: 2019-08-14

Total Pages: 616

ISBN-13: 9781493993130

DOWNLOAD EBOOK

This volume provides in-depth descriptions and discussion of clinical trial designs based on novel data analysis of high-quality trials for 11 different neurological conditions in order to ultimately improve the quality of care in neurology. Some of the conditions discussed in this book are stroke, traumatic brain injury, Alzheimer’s disease, epilepsy, and tumors of the central nervous system. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your research center and clinical investigation. Thorough and comprehensive, Clinical Trials in Neurology is a valuable guide for individuals in the research, education, and clinical practice fields, specifically in the fields of medicine, physical therapy, occupational therapy, nursing, and public health. This volume is also an important resource for clinicians aiming to improve their understanding in methodology of clinical trials.

The Handbook of Clinical Trials and Other Research
The Handbook of Clinical Trials and Other Research

Author: Alan Earl-Slater

Publisher: Radcliffe Publishing

Published: 2002

Total Pages: 364

ISBN-13: 9781857754858

DOWNLOAD EBOOK

This practical handbook includes all the main clinical trial and general research terms, and is illustrated with real-life examples, diagrams and tables. It also includes material on research ethical committees, and incorporates recent international developments such as the EU Clinical Trials Directive. The research methods and issues identified are universal, crossing countries and disciplines. It can be used as a reference tool, an introduction to learning about clinical trials, as a refresher to those involved in clinical research, or to check that the correct terms are being used in the correct context. Readily available references are included that can be used by the reader to further support their own work.

Handbook of Neurocritical Care
Handbook of Neurocritical Care

Author: Anish Bhardwaj

Publisher: Springer Science & Business Media

Published: 2004-05-25

Total Pages: 345

ISBN-13: 1592597726

DOWNLOAD EBOOK

Neurocritical care as a subspecialty has grown rapidly over the last 20 years with the advent of newer monitoring and diagnostic techniques and therapeutic modalities in a variety of brain and spinal cord injury paradigms. This handbook will serve as a quick reference guide to all health care providers in a neurocritical care setting. Since time is of the essence in the rapid diagnosis and timely therapeutic interventions for these patients, this book provides an algorithmic approach to making a clinical diagnosis using ancillary investigations to confirm the diagnosis and provide appropriate management of acute neurologic diseases. Tables and illustrations help provide a quick and easy bedside reference and give a practical approach to the management of these patients.

The Handbook of Neuroprotection
The Handbook of Neuroprotection

Author: Kewal K. Jain

Publisher: Humana

Published: 2020-08-14

Total Pages: 0

ISBN-13: 9781493994670

DOWNLOAD EBOOK

This fully revised edition explores the management of neurological disorders with a focus on neuroprotection, disease modification, and neuroregeneration rather than symptomatic treatment. Since the publication of the first edition, advances in biotechnology, particularly in cell and gene therapies, are reflected in this volume, as are numerous new and repurposed drugs in clinical trials. Overall, The Handbook of Neuroprotection serves as a comprehensive review of neuroprotection based on knowledge of the molecular basis of disorders of the central nervous system. In-depth and authoritative, The Handbook of Neuroprotection, Second Edition features a compendium of vital knowledge aimed at providing researchers with an essential reference for this key neurological area of study.

Successful Randomized Trials
Successful Randomized Trials

Author: Michael J. Domanski

Publisher: Lippincott Williams & Wilkins

Published: 2009

Total Pages: 228

ISBN-13: 9780781779456

DOWNLOAD EBOOK

This handbook is a ready reference on the theory and operation of modern large, multicenter randomized clinical trials, which have come to be the basis of evidence-based medicine. Written in a concise, engaging style geared to physicians, the book explains the rationale and theoretical foundations for clinical trials, the components of modern clinical trials including their functions and interactions, and practical considerations in the design and implementation of these studies including an introduction to the economics and business aspects.