This handbook provides a useful guide to preparing molecularly imprinted polymers (MIPs) for diverse practical applications. The first chapter covers the general aspects of molecular imprinting technology. The following chapters focus on specific applications, such as MIPs for sample concentration, MIPs for chromatography and related techniques, MIPs as sensor components, MIPs as traps for medical and bioremediation, MIPs as catalysts and artificial enzymes, and MIPs as components of drug delivery systems. All chapters of the handbook follow a common structure: interest of the MIP approach for that application specific aspects of the synthesis of MIPs for this aim (requirements and general recipes) representative examples of MIPs and their performance for that application a look to the future.
Molecular imprinting focuses on the fabrication of an artificial receptor with perfect molecular recognition abilities. It has attracted a great deal of scientific attention because of the enormous opportunities it opens in the fields of separation, catalysis, and analysis. The advantages of the molecular imprinting enable to target a wide class of substances ranging from small molecules to big conglomerates, such as proteins or even cells. In recent years, sensor applications based on molecular imprinting have started to attract greater attention because of the easy creation of robust receptor sites with high specificity and sensitivity toward a target compound. A collection of contributions from distinguised experts, Handbook of Molecular Imprinting: Advanced Sensor Applications provides a comprehensive overview on the specific challenges of molecular imprinting in sensor applications. It covers various molecular imprinting approaches. As a result, a perspective of future device ensembles for sensing is acquired. The text lays particular emphasis on fundamental aspects as well as novel ideas in the context of sensor applications. It also highlights the operation principles of various sensor transducers that are generally employed in combination with molecular imprinting recognition elements.
Bioanalytical Separations is volume 4 of the multi-volume series, Handbook of Analytical Separations, providing reviews of analytical separation methods and techniques used for the determination of analytes across a whole range of applications. The theme for this volume is bioanalysis, in this case specifically meaning the analysis of drugs and their metabolites in biological fluids.- Discusses new developments in instrumentation and methods of analyzing drugs and their metabolites in biological fluids - Provides guidance to the different methods, their relative value to the user, and the advantages and pitfalls of their use - Future trends are identified, in terms of the potential impact of new technologies
Molecular imprinting is one of the most efficient methods to fabricate functional polymer structures with pre-defined molecular recognition selectivity. Molecularly imprinted polymers (MIPs) have been used as antibody and enzyme mimics in a large number of applications. The outstanding stability and straightforward preparation make MIPs ideal substitutes for biologically derived molecular recognition materials, especially for development of affinity separation systems, chemical sensors and high selectivity catalysts. New MIP materials are being increasingly applied to solve challenging problems in environmental sciences, food safety control, biotechnology and medical diagnostics. Development in molecular imprinting research over the past decade has enabled tailor-designed molecular recognition sites to be created in synthetic materials with physical dimensions in the micro- and nano-regime. The new breakthroughs in MIP synthesis/fabrication have brought in many unprecedented functions of the micro- and nano-structured polymers. The aim of this review volume is to introduce to the readers the new developments in molecularly imprinted micro- and nano-structures, and the new applications that have been made possible with the new generation of imprinted materials.
This book is divided into 5 sections starting with an historic perspective and fundamental aspects on the synthesis and recognition by imprinted polymers. The second section contains 8 up-to-date overview chapters on current approaches to molecular and ion imprinting. This is followed by two chapters on new material morphologies and in the last two sections various analytical applications of imprinted polymers are given, with the last four chapters devoted to the promising field of imprinted polymers in chemical sensors.The authors of this volume have widely different backgrounds; mainly polymer chemistry, organic chemistry, biochemistry and analytical chemistry, which means that this book has an interdisciplinary character and should appeal to a broad audience.
Molecular imprinting technology has become a relevant tool for the synthesis of polymeric materials with the unique feature of being able to recognise specific target molecules and to bind them preferably among many others. Such an outstanding property makes molecularly imprinted polymer(s) (MIP) well suited for a wide range of applications in fields as diverse as analytical techniques, bioremediation, catalysis or drug delivery. Information regarding MIP has exponentially increased in recent years, being collected in a large variety of scientific journals, monographs and proceedings.This Handbook provides an overview of the state of the art of MIP by organising the information in an educational and practical way, with useful guidelines for newcomers to the field regarding monomer selection, polymerisation conditions and MIP conditioning for each given purpose.
Polymers are one of the most fascinating materials of the present era finding their applications in almost every aspects of life. Polymers are either directly available in nature or are chemically synthesized and used depending upon the targeted applications.Advances in polymer science and the introduction of new polymers have resulted in the significant development of polymers with unique properties. Different kinds of polymers have been and will be one of the key in several applications in many of the advanced pharmaceutical research being carried out over the globe. This 4-partset of books contains precisely referenced chapters, emphasizing different kinds of polymers with basic fundamentals and practicality for application in diverse pharmaceutical technologies. The volumes aim at explaining basics of polymers based materials from different resources and their chemistry along with practical applications which present a future direction in the pharmaceutical industry. Each volume offer deep insight into the subject being treated. Volume 1: Structure and Chemistry Volume 2: Processing and Applications Volume 3: Biodegradable Polymers Volume 4: Bioactive and Compatible Synthetic/Hybrid Polymers
A comprehensive guide to smart materials and how they are used in sample preparation, analytical processes, and applications This comprehensive, two-volume handbook provides detailed information on the present state of new materials tailored for selective sample preparation and the legal frame and environmental side effects of the use of smart materials for sample preparation in analytical chemistry, as well as their use in the analytical processes and applications. It covers both methodological and applied analytical aspects, relating to the development and application of new materials for solid-phase extraction (SPE) and solid-phase microextraction (SPME), their use in the different steps and techniques of the analytical process, and their application in specific fields such as water, food, air, pharmaceuticals, clinical sciences and forensics. Every chapter in Handbook of Smart Materials in Analytical Chemistry is written by experts in the field to provide a comprehensive picture of the present state of this key area of analytical sciences and to summarize current applications and research literature in a critical way. Volume 1 covers New Materials for Sample Preparation and Analysis. Volume 2 handles Analytical Processes and Applications. Focuses on the development and applications of smart materials in analytical chemistry Covers both, methodological and applied analytical aspects, for the development of new materials and their use in the different steps and techniques of the analytical process and their application in specific fields Features applications in key areas including water, air, environment, pharma, food, forensic, and clinical Presents the available tools for the use of new materials suitable to aid recognition process to the sample preparation and analysis A key resource for analytical chemists, applied laboratories, and instrument companies Handbook of Smart Materials in Analytical Chemistry, 2V Set is an excellent reference book for specialists and advanced students in the areas of analytical chemistry, including both research and application environments.
Mip Synthesis, Characteristics and Analytical Application, Volume 86 in the Comprehensive Analytical Chemistry series, highlights advances in the field, with this new volume presenting interesting chapters on synthesis and polymerization techniques of molecularly imprinted polymers, Solid phase extraction technique as a general field of application of molecularly imprinted polymer materials, Advanced artificially receptor- based sorbents for solid phase extraction using molecular imprinting technology: a new trend in food analysis, Application of molecularly imprinted polymers in microextraction and solventless extraction techniques, Magnetic molecularly imprinted microspheres – analytical approach, Surface Imprinted Micro- and Nanoparticles, and much more. - Contains a valuable source of information on the wide spectrum of application fields of molecularly imprinted polymers as a green sorption medium - Describes the application potential of currently molecular imprinting technologies, associated with the solid phase extraction techniques, magnetic imprinted microspheres, sorbents in mass spectrometry, and imprinted polymer electrochemical sensors
