Proteases as Targets for Therapy
Author: Klaus, von der Helm
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 427
ISBN-13: 3642570925
DOWNLOAD EBOOKWith contributions by numerous experts
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Handbook of Assay Development in Drug Discovery
Author: Lisa K. Minor
Publisher: CRC Press
Published: 2006-01-20
Total Pages: 490
ISBN-13: 1420015702
DOWNLOAD EBOOKThe Handbook of Assay Development in Drug Discovery describes all the tools currently available for performing various assay techniques. Featuring troubleshooting advice for common problems from experienced assay developers, the vendor community, and scientists in the pharmaceutical industry, the book presents descriptions of methods, laboratory guidelines and protocols used to perform such methods, specific examples of each assay system, and troubleshooting tools. Designed as a guide to running an assay from start to finish, this is an ideal bench top companion for scientists involved in drug discovery screening, lead profiling, therapeutic target evaluation, and assay development and implementation.
Frontiers in Clinical Drug Research - HIV
Author: Atta-ur-Rahman
Publisher: Bentham Science Publishers
Published: 2019-02-26
Total Pages: 168
ISBN-13: 1681085267
DOWNLOAD EBOOKFrontiers in Clinical Drug Research – HIV is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of acquired immune deficiency syndrome (AIDS) and other disorders associated with human immunodeficiency virus (HIV) infection. The scope of the book series covers a range of topics including the medicinal chemistry and pharmacology of natural and synthetic drugs employed in the treatment of AIDS (including HAART) and resulting complications, and the virology and immunological study of HIV and related viruses. Frontiers in Clinical Drug Research – HIV is a valuable resource for pharmaceutical scientists, clinicians and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in HIV/AIDS research. The fourth volume of this series features 5 chapters that cover these topics: - Design and Synthesis of HIV-1 Protease Inhibitors - Potential Magnetic Nanotherapeutics for Management of neuroAIDS - Syntheses of FDA Approved Integrase Inhibitor HIV Drugs and Improved Manufacturing using Flow Processing - The Development and Clinical Progress on Chemokine Receptor-Based HIV Entry Inhibitors - Sexually Transmitted Co-infections in Persons Living with HIV
Cell Surface Proteases
Author:
Publisher: Elsevier
Published: 2003-05-03
Total Pages: 475
ISBN-13: 0080490883
DOWNLOAD EBOOKCell Surface Proteases provides a comprehensive overview of these important enzymes that catalyze the hydrolysis of a protein as it degrades to a simpler substance. In the 1990s, an explosion of new discoveries shed light on the role of cell surface proteases and extended it beyond degradation of extracellular matrix components to include its influence on growth factors, cell signaling, and other cellular events. This volume unites the scientific literature from across disciplines and teases out unified themes of interactions between cell surface proteases and interconnecting cell surface-related systems -- including integrins and other adhesion molecules. Scientists and students involved in developmental biology, cell biology and disease processes will find this an indispensable resource.* Provides an overview of the entire field of cell surface proteases in a single volume* Presents major issues and astonishing discoveries at the forefront of modern developmental biology and developmental medicine * A thematic volume in the longest-running forum for contemporary issues in developmental biology with over 30 years of coverage
Therapy of Viral Infections
Author: Wibke E. Diederich
Publisher: Springer
Published: 2015-05-22
Total Pages: 231
ISBN-13: 3662467593
DOWNLOAD EBOOKMedicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.
Handbook of Proteases in Cancer
Author: Sajal Chakraborti
Publisher: CRC Press
Published: 2024-12-17
Total Pages: 459
ISBN-13: 1040166547
DOWNLOAD EBOOKThis handbook provides comprehensive coverage of the application of proteases in cancer therapy. Proteases make up to two percent of the human genome and play a critical role in the tumor microenvironment. The book delves into the applications of natural, synthetic, and non-coding RNAs in cancer therapy. It highlights how effective targeting of relevant proteases can help in cancer diagnosis and treatment. It covers the systems biology and bioinformatics approach in cancer drug development. The book is meant for researchers and professionals in cancer research, biochemistry, and physiology.
The British National Bibliography
Author: Arthur James Wells
Publisher:
Published: 2003
Total Pages: 2248
ISBN-13:
DOWNLOAD EBOOKHandbook of Cannabis and Related Pathologies
Author: Victor R Preedy
Publisher: Academic Press
Published: 2016-12-31
Total Pages: 1382
ISBN-13: 012800827X
DOWNLOAD EBOOKHandbook of Cannabis and Related Pathologies: Biology, Pharmacology, Diagnosis, and Treatment is the first book to take an interdisciplinary approach to the understanding of cannabis use and misuse. Recent worldwide trends toward decriminalizing marijuana for medical use have increased legal use of the drug and recreational use remains high, making cannabis one of the most commonly used drugs. Cannabis has a wide range of adverse neurological effects, and use and abuse can lead to physical, social, and psychopathological issues that are multifarious and complex. Effective understanding and treatment requires knowledge of the drug's effects from across scientific disciplines. This book provides an overview of the biological and pharmacological components of the cannabis plant, outlines its neurological, social, and psychopathological effects, assists in the diagnosis and screening for use and dependency, and aids researchers in developing effective treatments for cannabis-related issues and disorders. Fully illustrated, with contributions from internationally recognized experts, it is the go-to resource for neuroscientists, pharmacologists, pathologists, public-health workers, and any other researcher who needs an in-depth and cross-disciplinary understanding of cannabis and its effects. - Comprehensive chapters include an abstract, key facts, mini dictionary of terms, and summary points - Presents illustrations with at least six figures, tables, and diagrams per chapter - Provides a one-stop-shopping synopsis of everything to do with cannabis and its related pathology, from chemicals and cells, individuals and communities, and diagnosis and treatment - Offers an integrated and informed synopsis of the complex issues surrounding cannabis as a substance, its use, and its misuse
Subject Guide to Books in Print
Author:
Publisher:
Published: 1997
Total Pages: 3310
ISBN-13:
DOWNLOAD EBOOKPrevention and Treatment of Atherosclerosis
Author: Arnold von Eckardstein
Publisher: Springer Nature
Published: 2022
Total Pages: 537
ISBN-13: 3030860760
DOWNLOAD EBOOKThis open access book is supported by the European Atherosclerosis Society Association (EAS). This follow-up edition of the well-received Handbook volume 'Atherosclerosis: Diet and Drugs' reflects the state-of-the-art and most recent developments in atherosclerosis research. Outstanding international experts give a comprehensive overview of the field covering topics, such as improving the treatment focusing on established targets, novel drug developments addressing pre-defined targets, hypothesis-based and hypothesis-free approaches to unravel novel targets.
