Handbook of DNA Forensic Applications and Interpretation
Handbook of DNA Forensic Applications and Interpretation

Author: Amit Kumar

Publisher: Springer Nature

Published: 2022-07-01

Total Pages: 190

ISBN-13: 9811900434

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This handbook covers tested and proven DNA forensic testing methodologies, forensic bioinformatics techniques, case studies and current forensic legal framework for investigation of variety of crimes and provides a clinching evidence for speedy justice. DNA testing is widely used for forensic purposes and is changing the paradigm of (crime) investigation. The book contains chapters on usage of ultramodern DNA collection kits, presents era evidence collection and preservation, high-end DNA sample analysis in laboratory, DNA legislation, expert evidences, challenging and successful case studies, data generation and application of AI and IoT techniques for DNA data analysis, DNA databanks and training manpower to facilitate timely reporting to the requesting agencies. This handbook equips and enables police, investigators and crime analysis laboratories with knowhow of high-end tools, procedures and techniques to link or exclude a criminal to a crime. It is expected that this will be used by first responders, police, forensic analysts, judiciaries, evidence handlers and students and scholars of criminology and forensic sciences worldwide. The intention to write this handbook is to make DNA technology and its importance reach every common man and professional for correctly using it as a tool as and when required. This is quite evident that awareness of DNA technology has increased at a reasonable pace. Courts and investigating agencies are convinced and confident with its accuracy, reliability and unmatched peace delivered by various techniques of DNA fingerprinting and DNA profiling.

Forensic DNA Analysis
Forensic DNA Analysis

Author: J. Thomas McClintock

Publisher: CRC Press

Published: 2008-02-19

Total Pages: 165

ISBN-13: 1040084222

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In its short but active history, the use of DNA typing has revolutionized criminal investigations. It is almost inconceivable to bring a case to trial without positive identification through what is now our most accurate means. Proficiency with the methodology, principles, and interpretation of DNA evidence is crucial for today‘s criminalist.

Fundamentals of Forensic DNA Typing
Fundamentals of Forensic DNA Typing

Author: John M. Butler

Publisher: Academic Press

Published: 2009-09-30

Total Pages: 519

ISBN-13: 0080961762

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Fundamentals of Forensic DNA Typing is written with a broad viewpoint. It examines the methods of current forensic DNA typing, focusing on short tandem repeats (STRs). It encompasses current forensic DNA analysis methods, as well as biology, technology and genetic interpretation. This book reviews the methods of forensic DNA testing used in the first two decades since early 1980's, and it offers perspectives on future trends in this field, including new genetic markers and new technologies. Furthermore, it explains the process of DNA testing from collection of samples through DNA extraction, DNA quantitation, DNA amplification, and statistical interpretation. The book also discusses DNA databases, which play an important role in law enforcement investigations. In addition, there is a discussion about ethical concerns in retaining DNA profiles and the issues involved when people use a database to search for close relatives. Students of forensic DNA analysis, forensic scientists, and members of the law enforcement and legal professions who want to know more about STR typing will find this book invaluable. - Includes a glossary with over 400 terms for quick reference of unfamiliar terms as well as an acronym guide to decipher the DNA dialect - Continues in the style of Forensic DNA Typing, 2e, with high-profile cases addressed in D.N.A.Boxes-- "Data, Notes & Applications" sections throughout - Ancillaries include: instructor manual Web site, with tailored set of 1000+ PowerPoint slides (including figures), links to online training websites and a test bank with key

Forensic DNA Profiling
Forensic DNA Profiling

Author: Jo-Anne Bright

Publisher: CRC Press

Published: 2019-12-09

Total Pages: 192

ISBN-13: 0429671423

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DNA testing and its forensic analysis are recognized as the “gold standard” in forensic identification science methods. However, there is a great need for a hands-on step-by-step guide to teach the forensic DNA community how to interpret DNA mixtures, how to assign a likelihood ratio, and how to use the subsequent likelihood ratio when reporting interpretation conclusions. Forensic DNA Profiling: A Practical Guide to Assigning Likelihood Ratios will provide a roadmap for labs all over the world and the next generation of analysts who need this foundational understanding. The techniques used in forensic DNA analysis are based upon the accepted principles of molecular biology. The interpretation of a good-quality DNA profile generated from a crime scene stain from a single-source donor provides an unambiguous result when using the most modern forensic DNA methods. Unfortunately, many crime scene profiles are not single source. They are described as mixed since they contain DNA from two or more individuals. Interpretation of DNA mixtures represents one of the greatest challenges to the forensic DNA analyst. As such, the book introduces terms used to describe DNA profiles and profile interpretation. Chapters explain DNA extraction methods, the polymerase chain reaction (PCR), capillary electrophoresis (CE), likelihood ratios (LRs) and their interpretation, and population genetic models—including Mendelian inheritance and Hardy-Weinberg equilibrium. It is important that analysts understand how LRs are generated in a probabilistic framework, ideally with an appreciation of both semicontinuous and fully continuous probabilistic approaches. KEY FEATURES: • The first book to focus entirely on DNA mixtures and the complexities involved with interpreting the results • Takes a hands-on approach offering theory with worked examples and exercises to be easily understood and implementable by laboratory personnel • New methods, heretofore unpublished previously, provide a means to innovate deconvoluting a mixed DNA profile, assign an LR, and appropriately report the weight of evidence • Includes a chapter on assigning LRs for close relatives (i.e., “It’s not me, it was my brother”), and discusses strategies for the validation of probabilistic genotyping software Forensic DNA Profiling fills the void for labs unfamiliar with LRs, and moving to probabilistic solutions, and for labs already familiar with LRs, but wishing to understand how they are calculated in more detail. The book will be a welcome read for lab professionals and technicians, students, and legal professionals seeking to understand and apply the techniques covered.

The Evaluation of Forensic DNA Evidence
The Evaluation of Forensic DNA Evidence

Author: National Research Council

Publisher: National Academies Press

Published: 1996-12-12

Total Pages: 270

ISBN-13: 0309134404

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In 1992 the National Research Council issued DNA Technology in Forensic Science, a book that documented the state of the art in this emerging field. Recently, this volume was brought to worldwide attention in the murder trial of celebrity O. J. Simpson. The Evaluation of Forensic DNA Evidence reports on developments in population genetics and statistics since the original volume was published. The committee comments on statements in the original book that proved controversial or that have been misapplied in the courts. This volume offers recommendations for handling DNA samples, performing calculations, and other aspects of using DNA as a forensic toolâ€"modifying some recommendations presented in the 1992 volume. The update addresses two major areas: Determination of DNA profiles. The committee considers how laboratory errors (particularly false matches) can arise, how errors might be reduced, and how to take into account the fact that the error rate can never be reduced to zero. Interpretation of a finding that the DNA profile of a suspect or victim matches the evidence DNA. The committee addresses controversies in population genetics, exploring the problems that arise from the mixture of groups and subgroups in the American population and how this substructure can be accounted for in calculating frequencies. This volume examines statistical issues in interpreting frequencies as probabilities, including adjustments when a suspect is found through a database search. The committee includes a detailed discussion of what its recommendations would mean in the courtroom, with numerous case citations. By resolving several remaining issues in the evaluation of this increasingly important area of forensic evidence, this technical update will be important to forensic scientists and population geneticistsâ€"and helpful to attorneys, judges, and others who need to understand DNA and the law. Anyone working in laboratories and in the courts or anyone studying this issue should own this book.

Forensic Chemistry Handbook
Forensic Chemistry Handbook

Author: Lawrence Kobilinsky

Publisher: John Wiley & Sons

Published: 2011-11-29

Total Pages: 548

ISBN-13: 0471739545

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A concise, robust introduction to the various topics covered by the discipline of forensic chemistry The Forensic Chemistry Handbook focuses on topics in each of the major chemistry-related areas of forensic science. With chapter authors that span the forensic chemistry field, this book exposes readers to the state of the art on subjects such as serology (including blood, semen, and saliva), DNA/molecular biology, explosives and ballistics, toxicology, pharmacology, instrumental analysis, arson investigation, and various other types of chemical residue analysis. In addition, the Forensic Chemistry Handbook: Covers forensic chemistry in a clear, concise, and authoritative way Brings together in one volume the key topics in forensics where chemistry plays an important role, such as blood analysis, drug analysis, urine analysis, and DNA analysis Explains how to use analytical instruments to analyze crime scene evidence Contains numerous charts, illustrations, graphs, and tables to give quick access to pertinent information Media focus on high-profile trials like those of Scott Peterson or Kobe Bryant have peaked a growing interest in the fascinating subject of forensic chemistry. For those readers who want to understand the mechanisms of reactions used in laboratories to piece together crime scenes—and to fully grasp the chemistry behind it—this book is a must-have.

The Forensic Laboratory Handbook Procedures and Practice
The Forensic Laboratory Handbook Procedures and Practice

Author: Ashraf Mozayani

Publisher: Springer Science & Business Media

Published: 2010-12-14

Total Pages: 604

ISBN-13: 1607618729

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Forensic science has come a long way in the past ten years. It is much more in-depth and much broader in scope, and the information gleaned from any evidence yields so much more information than it had in the past because of incredible advances in analytic instruments and crucial procedures at both the crime scene and in the lab. Many practices have gone digital, a concept not even fathomed ten years ago. And from the first collection of evidence to its lab analysis and interpretation to its final presentation in court, ethics has become an overriding guiding principle. That’s why this new edition of this classic handbook is indispensable. The Forensic Laboratory Handbook Procedures and Practice includes thirteen new chapters written by real-life practitioners who are experts in the field. It covers the tried and true topics of fingerprints, trace evidence, chemistry, biology, explosives and arson, forensic anthropology, forensic pathology, forensic documents, firearms and toolmarks. This text also addresses an array of new topics including accreditation, certification, ethics, and how insects and bugs can assist in determining many facts including a margin of time of death. In the attempt to offer a complete and comprehensive analysis The Forensic Laboratory Handbook Procedures and Practice also includes a chapter discussing the design of a laboratory. In addition, each chapter contains educational requirements needed for the discipline it covers. Complete with questions at the end of each chapter, brief author bios and real crime scene photos, this text has risen to greet the many new challenges and issues that face today’s forensic crime practitioners.

An Introduction to Forensic Genetics
An Introduction to Forensic Genetics

Author: William Goodwin

Publisher: John Wiley & Sons

Published: 2007-11-27

Total Pages: 170

ISBN-13: 0470010258

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An Introduction to Forensic Genetics is a comprehensive introduction to this fast moving area from the collection of evidence at the scene of a crime to the presentation of that evidence in a legal context. The last few years have seen significant advances in the subject and the development and application of genetics has revolutionised forensic science. This book begins with the key concepts needed to fully appreciate the subject and moves on to examine the latest developments in the field, illustrated throughout with references to relevant casework. In addition to the technology involved in generating a DNA profile, the underlying population biology and statistical interpretation are also covered. The evaluation and presentation of DNA evidence in court is discussed as well with guidance on the evaluation process and how court reports and statements should be presented. An accessible introduction to Forensic Genetics from the collection of evidence to the presentation of that evidence in a legal context Includes case studies to enhance student understanding Includes the latest developments in the field focusing on the technology used today and that which is likely to be used in the future Accessible treatment of population biology and statistics associated with forensic evidence This book offers undergraduate students of Forensic Science an accessible approach to the subject that will have direct relevance to their courses. An Introduction to Forensic Genetics is also an invaluable resource for postgraduates and practising forensic scientists looking for a good introduction to the field.

Genetic Witness
Genetic Witness

Author: United States. Congress. Office of Technology Assessment

Publisher:

Published: 1990

Total Pages: 208

ISBN-13:

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