Hairless Animals looks at those animals without hair. This title shows examples of dogs, cats, pigs, dolphins, and more. It also discusses what they feel like to touch and why some animals don't even need hair. With very easy text and colorful images showing a variety of different animals, young readers will gain a better understanding of our bald friends. Aligned to Common Core Standards and correlated to state standards. Abdo Kids is a division of ABDO.
Perfect for animal lovers of all ages, this entertaining and wacky book is jam-packed with hundreds of mind-blowing visual comparisons and astonishing facts. Every page reveals incredible information about the weird and wonderful world of animals. Can you believe an ant recently discovered in the treetops of Borneo explodes when under attack, covering enemy ants in a toxic goo? Did you know that the ocean-dwelling bootlace worm is longer than an Olympic-sized swimming pool? "But it can't be true," you say. Yes, it really is! It Can't Be True! Animals bring you record-breaking facts and amazing stories that you can see for yourself. Eye-popping photos and stunning illustrations show you what the numbers mean, comparing the extraordinary with the familiar. From the coconut crab that grows bigger than a basketball to the Ruppell's vulture that soars higher than an airplane, this unique book for kids shows you what other books only tell you. Featuring astounding animals from all the main groups - invertebrates, fish, amphibians, reptiles, birds, and mammals - this is the perfect gift for children who are curious about the animal kingdom.
Tiselius demonstrated that the immunologically active components of immune sera migrated electrophoretically in the gamma globulin region. His findings illuminated the classic observations of Jenner regarding development of resistance to infection, and those of von Pirquet, Pasteur, and Arthus regarding the transfer and specificity of resistance. Conceptual integration of these observations provided the impetus for the present modern era of immunology. Subsequent to Tiselius's work, multiple, rapid advances have occurred in the study of congenital and acquired immune deficiency states in mice, chickens, and humans. These studies have readily demonstrated that the immunologic ability of an organ ism to protect itself from environmental influences is a prerequisite for survival. Indeed, this necessity for protection from microenvironmental influences has promoted the evolu tionary development of immunologic diversification, namely, host dependence upon a sophisticated, multifaceted network of cells and effector mechanisms responsible for the clearance and neutralization of toxins and potentially harmful pathogens. The obligate dependence of animals upon the functional integrity of their immunologic systems is illus trated by the ready invasion of ubiquitous organisms when the host is in a state of immune defense derangement. Nevertheless, derangements in immune function can range from par tial to complete and can be compatible with survival. The consequences of such derange ments run the gamut from subclinical disease to inevitable mortality.
Spotted Animals looks at those animals that have spots. This title shows examples of dogs, horses, geckos, cows, and more. It also discusses why some animals have spots and how that can help them. With very easy text and colorful images showing a variety of different animals, young readers will gain a better understanding of our speckled friends. Aligned to Common Core Standards and correlated to state standards. Abdo Kids is a division of ABDO.
Striped Animals highlights animals that have stripes. This title shows examples of tigers, chipmunks, bees, skunks, and more. It discusses why some animals have stripes, how that helps them, and how it can be a warning for us and other animals. With easy text and colorful images showing a variety of animals, young readers will gain a better understanding of our banded friends. Aligned to Common Core Standards and correlated to state standards. Abdo Kids is a division of ABDO.
Slimy Animals showcases the oozing, mucus-producing animals. This title shows examples of slugs, eels, frogs, octopuses, and more. It also discusses what they feel like to touch, how some animals use slime for travel, and how others use it for defense. With easy text and colorful images showing a variety of animals, young readers will gain a better understanding of our gooey friends. Aligned to Common Core Standards and correlated to state standards. Abdo Kids is a division of ABDO.
Principles of Animal Extrapolation addresses the conceptual basis for animal extrapolation and provides an abundance of documentation that illustrates how these principles may be applied in the selection of the more appropriate models and in the interpretation of toxicological studies. The book analyzes and documents each specific biological cause of interspecies differences in susceptibility to toxic agents, including differences in absorption, gut flora, tissue distribution, metabolism, mechanisms and efficiencies of repair, and excretion. The problem of the heterogenicity of the human population is addressed through several chapters that assess the availability and prospects of developing predictive animal models for normal humans, as well as selected potential high-risk groups. Other topics presented in this book include the biological basis of regulatory actions involving attempts to extrapolate from exceptionally high exposure levels to realistic values, especially carcinogens; an assessment of genotoxicity tests, their ability to predict carcinogenicity in whole animals, and the manner in which they should be used by regulatory agencies; birth defects; and predicting the risk of human teratogenesis. Principle of Animal Extrapolation is essential for environmental toxicologists. It also provides valuable information to biomedical scientists (especially those involved in drug development and testing) and regulatory personnel in agencies such as the EPA, the OSHA, the NIOSH, and the FDA.
A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.