Guide to Techniques in Mouse Development, Part A

Guide to Techniques in Mouse Development, Part A

Author:

Publisher: Academic Press

Published: 2010-09-09

Total Pages: 536

ISBN-13: 9780123747754

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Guide to Techniques in Mouse Development, Part A comprehensively covers new technologies and methodologies that have appeared for the study of mouse development. Update of volume 225 of Methods in Enzymology, Guide to Techniques in Mouse Development, edited by P.M. Wassarman and M.L. DePamphilis and published in 1993 Covers new technologies and methodologies, including: new techniques for the cryopreservation of gametes and embryos production of transgenic and null (knockout) animals (use of ES cells) generation of conditional/inducible mutant animals use of gene-trap mutagenesis analysis of allele-specific expresion use of new reporter constructs humanizing of transgenic animals transcript profiling of mouse development imaging of mouse development rederivation of animals and use of mouse genomics


Guide to Techniques in Mouse Development

Guide to Techniques in Mouse Development

Author: Paul M. Wassarman

Publisher: Academic Press

Published: 2010

Total Pages: 580

ISBN-13: 9780123848826

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17 years have passed since the first edition of the Guide to Techniques in Mouse Development (volume 225) was published. During this time development of technology used to investigate mouse development has not stood still, with enormous advances occuring in genomics, transgenic and ES cell methodology, and reprogramming, culminating with development of iPS cells. At both the cellular and molecular levels, a great many technological advances have been made that permit investigators to probe ever more deeply into all aspects of mouse development. This completely new version of the Guide has been split into two parts, both highlighting the techonological advances used to study mouse development.


Guide to Techniques in Mouse Development, Part A

Guide to Techniques in Mouse Development, Part A

Author:

Publisher: Academic Press

Published: 2010-09-09

Total Pages: 536

ISBN-13: 9780123747754

DOWNLOAD EBOOK

Guide to Techniques in Mouse Development, Part A comprehensively covers new technologies and methodologies that have appeared for the study of mouse development. Update of volume 225 of Methods in Enzymology, Guide to Techniques in Mouse Development, edited by P.M. Wassarman and M.L. DePamphilis and published in 1993 Covers new technologies and methodologies, including: new techniques for the cryopreservation of gametes and embryos production of transgenic and null (knockout) animals (use of ES cells) generation of conditional/inducible mutant animals use of gene-trap mutagenesis analysis of allele-specific expresion use of new reporter constructs humanizing of transgenic animals transcript profiling of mouse development imaging of mouse development rederivation of animals and use of mouse genomics


Guide to Techniques in Mouse Development, Part A

Guide to Techniques in Mouse Development, Part A

Author:

Publisher: Academic Press

Published: 2010-08-26

Total Pages: 0

ISBN-13: 9780123747754

DOWNLOAD EBOOK

Guide to Techniques in Mouse Development, Part A comprehensively covers new technologies and methodologies that have appeared for the study of mouse development.


Guide to Techniques in Mouse Development, Part A

Guide to Techniques in Mouse Development, Part A

Author:

Publisher: Academic Press

Published: 2010-08-04

Total Pages: 539

ISBN-13: 0080887783

DOWNLOAD EBOOK

Guide to Techniques in Mouse Development, Part A comprehensively covers new technologies and methodologies that have appeared for the study of mouse development. Update of volume 225 of Methods in Enzymology, Guide to Techniques in Mouse Development, edited by P.M. Wassarman and M.L. DePamphilis and published in 1993 Covers new technologies and methodologies, including: new techniques for the cryopreservation of gametes and embryos production of transgenic and null (knockout) animals (use of ES cells) generation of conditional/inducible mutant animals use of gene-trap mutagenesis analysis of allele-specific expresion use of new reporter constructs humanizing of transgenic animals transcript profiling of mouse development imaging of mouse development rederivation of animals and use of mouse genomics


Guide to Techniques in Mouse Development, Part B

Guide to Techniques in Mouse Development, Part B

Author: Paul Wassarman

Publisher: Academic Press

Published: 2010-09-24

Total Pages: 637

ISBN-13: 0123848814

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This volume comprehensively covers new technologies and methodologies that have appeared for the study of mouse development Update of volume 225, Guide to Techniques in Mouse Development, edited by P.M. Wassarman and M.L. DePamphilis and published in 1993 Comprehensively covers: new techniques for the cryopreservation of gametes and embryos production of transgenic and null (knockout) animals (use of ES cells) generation of conditional/inducible mutant animals, use of gene-trap mutagenesis analysis of allele-specific expression, use of new reporter constructs humanizing of transgenic animals transcript profiling of mouse development imaging of mouse development rederivation of animals and use of mouse genomics


The Guide to Investigation of Mouse Pregnancy

The Guide to Investigation of Mouse Pregnancy

Author: B. Anne Croy

Publisher: Academic Press

Published: 2013-12-09

Total Pages: 829

ISBN-13: 0123947944

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The Guide to Investigation of Mouse Pregnancy is the first publication to cover the mouse placenta or the angiogenic tree the mother develops to support the placenta. This much-needed resource covers monitoring of the cardiovascular system, gestational programming of chronic adult disease, epigenetic regulation, gene imprinting, and stem cells. Offering detailed and integrated information on how drugs, biologics, stress, and manipulations impact pregnancy in the mouse model, this reference highlights techniques used to analyze mouse pregnancy. Joining the ranks of much referenced mouse resources, The Guide to Investigation of Mouse Pregnancy is the only manual providing needed content on pregnancy in animal models for translational medicine and research. Provides instruction on how to collect pre-clinical data on pregnancy in mouse models for eventual use in human applications Describes the angiogenic tree the mother’s uterus develops to support pregnancy and the monitoring of pregnancy-induced cardiovascular changes Educates readers on placental cell lineages, decidual development including immune cells, epigenetic regulation, gene imprinting, stem cells, birth and lactation Discusses how stress, environmental toxicants and other manipulations impact upon placental function and pregnancy success