Graves' Orbitopathy
Graves' Orbitopathy

Author: W.M. Wiersinga

Publisher: Karger Medical and Scientific Publishers

Published: 2010-08-17

Total Pages: 300

ISBN-13: 3805595328

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The significant progress in the understanding of the pathogenesis and the treatment of Graves’ orbitopathy (GO) has warranted a second edition of this book within three years of the first. Now also fully incorporated is the EUGOGO consensus statement on management of GO, which since has been accepted worldwide as a useful guideline. Furthermore all chapters have been thoroughly updated. Subjects covered include the pathology of GO and the controversial views on its pathogenesis; assessment of changes using reliable measuring techniques; medical management of GO including established and alternative treatment options; technical explanations and illustrations of various surgical procedures and finally, the molecular, immunologic, and clinical aspects of this complex disorder. Two new chapters have been added: one describing the socioeconomic impact of the disease and the other outlining the Amsterdam Declaration on Graves’ Orbitopathy. The successful question-and-answer format facilitates its use as a reference guide for medical practitioners and surgeons working in the fields of ophthalmology, internal medicine, endocrinology, pediatrics, immunology, as well as otorhinolaryngology.

Graves' Orbitopathy
Graves' Orbitopathy

Author: Wilmar M. Wiersinga

Publisher: Karger Medical and Scientific Publishers

Published: 2007

Total Pages: 275

ISBN-13: 3805583427

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In recent years, close interdisciplinary cooperation of numerous international experts, both clinicians and basic scientists, within the European Group of Graves' orbitopathy (EUGOGO) has yielded much valuable progress and new information, which this publication brings together. Subjects covered include the pathology of Graves' orbitopathy (GO) and the controversial views on its pathogenesis; assessment of changes using reliable measuring techniques; medical management of GO including established and alternative treatment options; technical explanations and illustrations of various surgical procedures and finally, the molecular, immunologic, and clinical aspects of this complex disorder. Stressing the current management of thyroid eye disease, this book offers medical practitioners a thorough overview of associated changes in the eyes of patients with GO. Therefore, this publication is an essential resource for ophthalmologists, internists, endocrinologists, pediatricians, immunologists, specialists in nuclear medicine, neuroradiologists and radiotherapists, specialists in laboratory medicine and pathology, otorhinolaryngologists, orbital and neurosurgeons as well as oral and maxillofacial surgeons.

Thyroid Autoimmunity
Thyroid Autoimmunity

Author: A. Pinchera

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 579

ISBN-13: 146130945X

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In 1956, three groups independently reported evidence that some thyroid disease appearing spontaneously in humans or experimentally induced in animals are related to autoimmune processes. The interval between these landmark discoveries and the present has witnessed a remarkable and continuing growth of both knowledge and concepts concerning the mechanisms of immune regulation, the pathogenesis of autoimmune thyroid diseases, and their clinical and laboratory manifestations. More importantly knowledge of thyroid autoimmunity has, in many respects, comprised the vanguard of an ever increasing appreciation and understanding of autoimmune diseases in general. On November 24-26 1986, an International Symposium on Thyroid Autoimmunity was held in Pisa. Its purpose was to commemorate the birth of thyroid autoimmunity as a scientific discipline, to summarize current knowledge and concepts in this area, and where possible, to anticipate areas of opportunity for the future - hence the theme of the Symposium, Memories and Perspectives. To open the meeting, the Magnifico Rettore (Chancellor) of the University of Pisa granted special Awards to Dr. Deborah Doniach, Dr. Ivan Roitt, and Dr. Noel R. Rose, who published the first fundamental studies in the field of thyroid autoimmunity, and to Dr. Duncan G. Adams, whose discovery of the long-acting thyroid stimulator (LATS) opened the door to our current understanding of the pathogenesis of Graves' disease. During the meeting thirty plenary lectures were presented.

Graves' Orbitopathy
Graves' Orbitopathy

Author: W M Wiersinga

Publisher: Karger Medical and Scientific Publishers

Published: 2017-08-21

Total Pages: 378

ISBN-13: 3318060844

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3rd, revised and expanded edition. Ten years ago, the first edition of Graves’ Orbitopathy: A Multidisciplinary Approach was published. Since then, the book has become very popular and much has happened in the field to warrant a third edition. What has not changed is the successful and attractive question-and-answer format of the book. In the 3rd, revised and expanded edition, new chapters have been added on co-morbidity, local treatment modalities, novel immunosuppressive therapy, detailed protocols, and questions frequently asked by patients. All chapters of the previous edition have been thoroughly updated. Subjects covered then include the pathology of Graves’ Orbitopathy (GO) and the controversial views on its pathogenesis; assessment of changes using reliable measuring techniques; medical management of GO including established and alternative treatment options; technical explanations and illustrations of various surgical procedures; and finally, the molecular, immunologic, and clinical aspects of this complex disorder. Additionally, ample consideration is given to the new 2016 ETA/EUGOGO guidelines on the management of GO.

Graves' Disease
Graves' Disease

Author: Rebecca S. Bahn

Publisher:

Published: 2015

Total Pages:

ISBN-13: 9781493925353

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This indispensable volume is designed to facilitate the best possible physician?patient discussion on Graves? disease by providing the most up-to-date evidence-based information in a clinically useful and patient-centric manner. Comprehensive and covering such topics as Professionalism and the Art of Patient-centric Thyroidology, the Immunopathogenesis of Graves? Disease, and the Diagnosis and Management of Thyroid Storm, the book addresses all the important refinements in the treatment of Graves? disease in recent years. These include new indications and contraindications for antithyroid drugs, improved approaches to radioactive iodine therapy, the development of novel surgical techniques, and a better understanding of the combined use of these modalities, among other developments. Also addressed are the advances in the treatment of GO, including the use of disease activity and severity assessments to inform management decisions and the completion of the first randomized controlled therapeutic trials. Developed by a renowned group of internationally respected authorities, Graves? Disease: A Comprehensive Guide for Clinicians is a significant new reference that will be of great interest to all clinicians who treat this debilitating condition.

Thyroid Eye Disease: Understanding Graves' Ophthalmopathy
Thyroid Eye Disease: Understanding Graves' Ophthalmopathy

Author: Edgar Harrison

Publisher: Foster Academics

Published: 2023-09-26

Total Pages: 0

ISBN-13: 9781646465491

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Graves' disease refers to a disorder affecting the immune system which leads to the overproduction of thyroid hormones. Graves' ophthalmopathy, also called Graves' orbitopathy, is an autoimmune disease affecting the retro-ocular tissues in patients having Graves' disease. It is primarily the disease of the orbit and can have severe implications, such as loss of sight. It causes swelling in the area around the eyes, which causes bulging of the eyes. The symptoms of Graves' ophthalmopathy include double vision, bulging eyes, swelling in the eyelids, vision loss, sensitivity to light, redness or inflammation, and difficulty in moving eyes. This disease results in increased extraocular muscle volume and orbital fat in the orbital space. The targets of autoimmune attack within Graves' ophthalmopathy are the fibroblasts residing in the orbital tissues. Radiation, immunosuppression and surgical procedures, like orbital decompression surgery, eye muscle surgery and eyelid surgery are utilized to treat severe forms of this disease. This book contains some path-breaking studies on Graves' Ophthalmopathy. It is a valuable compilation of topics, ranging from the basic to the most complex advancements in the study of this disease. The book will serve as a reference to a broad spectrum of readers.

Surgery in Thyroid Eye Disease
Surgery in Thyroid Eye Disease

Author: Suryasnata Rath

Publisher: Springer Nature

Published: 2020-07-31

Total Pages: 233

ISBN-13: 9813292202

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This surgical manual provides a step-by-step guide to various surgical procedures for patients with thyroid eye disease (TED). The key surgical steps are covered in detail, with intra-operative photographs. The manual addresses all aspects of TED, including the basic anatomy, surgical preparation, evaluation of imaging, and surgical procedures. TED is commonly encountered by oculoplastic surgeons and general ophthalmologists in their daily practice, and restoration of the normal appearance is vital to patients and their families. Surgical treatments for TED include basic oculoplastic surgery, complex eyelid surgery, strabismus surgery, orbital surgery, and aesthetic procedures. All of the contributing authors are eminent experts with vast experience in treating TED. High-resolution images will help readers understand the key surgical steps, and are combined with a minimal amount of text, reflecting the book’s focus on surgical technique. Offering a complete guide that contains all relevant surgical knowledge on TED, presented in a highly practice-oriented format, the book is a must-read for every surgeon whose work involves managing TED.

A Case-Based Guide to Clinical Endocrinology
A Case-Based Guide to Clinical Endocrinology

Author: Terry F. Davies

Publisher: Springer Nature

Published: 2022-01-04

Total Pages: 528

ISBN-13: 303084367X

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Now in a revised and expanded third edition, this case-based guide emphasizes the latest investigative advances in both imaging and molecular diagnostics and new treatment approaches for a wide variety of common and complex endocrine conditions. Utilizing unique clinical case histories, each main endocrine condition and disorder is curated by a senior Section Editor with an introduction to his or her area covering both physiology and pathophysiology. This introductory chapter is followed by a number of case histories written by invited experts and designed to cover the important relevant pathophysiology, following a consistent chapter format for ease of use, including bulleted objectives, case presentations, review of the diagnosis, lessons learned, and 3-5 multiple-choice review questions. Section headings include the pituitary, thyroid (overactivity, underactivity and cancer) and parathyroid, adrenal disorders, metabolic bone disease, type 2 diabetes, lipid abnormalities, obesity, and pregnancy. Topics new to this edition include PCOS, transgender medicine and the endocrine effects of viral infections. With a focus on covering major parts of the APDEM curriculum, A Case-Based Guide to Clinical Endocrinology remains a tremendous resource for junior and veteran clinicians alike.

Controversies in Neuro-Ophthalmic Management
Controversies in Neuro-Ophthalmic Management

Author: Amanda D. Henderson

Publisher: Springer Nature

Published: 2021-06-25

Total Pages: 282

ISBN-13: 3030741036

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This book functions as a resource for providers who treat patients with neuro-ophthalmic conditions. Using an evidence-based approach to controversial management decisions, the material is presented in a digestible, case-based format. Divided into six sections, the book begins with an introduction to its framework, format, and purpose. Following this, sections two, three, and four discuss various optic neuropathies, ocular motility disorders, and transient visual symptoms. The concluding sections then address neuro-ophthalmic manifestations of pain, including migraine and post-concussive syndrome, and systemic diseases, such as giant cell arteritis. Each chapter focuses on cases that are historically complex, or which have undergone a recent shift in traditional management due to new scientific discoveries or newly available therapies. Controversies in Neuro-Ophthalmic Management presents essential, thorough information on management options and the data for their use to provide the best care for patients.