Global Virology II - HIV and NeuroAIDS

Global Virology II - HIV and NeuroAIDS

Author: Paul Shapshak

Publisher: Springer

Published: 2017-10-07

Total Pages: 1059

ISBN-13: 1493972901

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This book on NeuroAIDS, a collection of chapters written by experts and specialists from around the world, provides a global perspective on HIV and NeuroAIDS in the field, clinic, and laboratory. The chapters address the comorbidity of HIV and other infectious agents, including Zika virus, Ebola, Chagas disease, TB and HCV. Also discussed are key topics, such as: · Molecular socioepidemiology · Global HIV and NeuroAIDS · Neuropathology · cART and blood-brain barrier penetration · HIV replicative oscillations · HIV and SIV evolution · Psychiatric comorbidities · Neurosyphilis · The examination of current and innovative models of translational research to translational effectiveness


Global Virology III: Virology in the 21st Century

Global Virology III: Virology in the 21st Century

Author: Paul Shapshak

Publisher: Springer Nature

Published: 2019-11-22

Total Pages: 671

ISBN-13: 3030290220

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Global Virology, Volume III: Virology in the 21st Century examines work that has been undertaken, or is planned, in several fields of virology, in an effort to promote current and future work, research, and health. Fields and methods addressed include virology, immunology, space research, astrovirology/astrobiology, plasmids, swarm intelligence, bioinformatics, data-mining, machine learning, neural networks, critical equations, and advances in biohazard biocontainment. Novel and forward-looking methods, techniques, and approaches in research and development are presented by experts in the field.


Bioinformation Discovery

Bioinformation Discovery

Author: Pandjassarame Kangueane

Publisher: Springer

Published: 2018-09-01

Total Pages: 226

ISBN-13: 3319953273

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This new edition continues to illustrate the power of biological data in knowledge discovery. It describes biological data types and representations with examples for creating a workflow in bioinformation discovery. The concepts in knowledge discovery from data are illustrated using line diagrams. The principles and concepts in knowledge discovery are used for the development of prediction models for simulations of biological reactions and events. Advanced topics in molecular evolution and cellular & molecular biology are addressed using bioinformation gleaned through discovery. Each chapter contains approximately 10 exercises for practice. This will help students to expand their problem solving skills in Bioinformation Discovery. In this new edition, there are three new chapters covering single nucleotide polymorphism, genes, proteins and disease, and protein functions driven by surface electrostatics.


HIV-Associated Neurocognitive Disorders

HIV-Associated Neurocognitive Disorders

Author: Guoku Hu

Publisher: Elsevier

Published: 2024-02-21

Total Pages: 654

ISBN-13: 0323997457

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HIV-Associated Neurocognitive Disorders: Molecular and Cellular Mechanisms and Clinical Manifestations is a comprehensive volume on the field of HIV-Associated Neurocognitive Disorders (HAND) as well as its associated comorbidities. Covering clinical manifestations as well as molecular and cellular mechanisms, this book discusses available macaque and rodent animal models of HAND, epigenetic regulation, and signaling pathways underlying symptoms. Chapters also cover prevention and therapeutic strategies, as well as diagnosis and biomarkers associated with disease outcomes. This volume is appropriate for basic research and clinical investigators working in the area of HIV-1 infection. - Provides an in-depth exploration of the clinical manifestations of HAND and its comorbidities - Includes detailed assessments of the molecular and cellular mechanisms underlying HAND symptoms - Examines animal models for studying HAND, including macaque and rodent models - Presents insights into epigenetic regulation and signaling pathways implicated in HAND - Covers prevention, therapeutic strategies, and diagnostic approaches


Microbiomes

Microbiomes

Author: Eugene Rosenberg

Publisher: Springer Nature

Published: 2021-03-02

Total Pages: 439

ISBN-13: 303065317X

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This book examines an important paradigm shift in biology: Plants and animals, traditionally viewed as individuals, are now considered to be complex systems and host to a plethora of microorganisms. After first presenting historical aspects of microbiota research, bacterial compositions of individual microbiomes and the critical analysis of current methods, the book discusses how microbial communities inside the human body are profoundly affected by numerous factors, such as macro- and micro-nutrients, physical exercise, antibiotics, gender and age. As described by current research, the author highlights how microbiomes contribute to the fitness of the host by providing nutrients, inhibiting pathogens, aiding in the storage of fat during pregnancy, and contributing to development and behavior. The author not only focusses on prokaryotic components in microbiomes, but also addresses single-cell eukaryotes and viruses. This follow-up to the successful book The Hologenome Concept: Human, Animal and Plant Microbiota, published in 2013, provides a contemporary overview of microbiomes. It appeals to anyone working in the life sciences and biomedicine.


Neuropsychology of Everyday Functioning

Neuropsychology of Everyday Functioning

Author: Thomas D. Marcotte

Publisher: Guilford Publications

Published: 2022-01-18

Total Pages: 760

ISBN-13: 1462548903

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The go-to resource for assessing and predicting functional abilities in persons with brain injury or cognitive decline has now been revised and expanded to reflect significant advances in the field. With a focus on key real-world capacities--independent living, vocational functioning, medication management, and driving--leading experts explore how individuals go about their daily lives, where and why disruptions occur, and potential opportunities for improving function. Strategies for direct assessment are reviewed, from standard neuropsychological tests to multimodal approaches and technology-based tools. Chapters also provide functional assessment guidance for specific neurological and psychiatric conditions: dementia, traumatic brain injury, depression, schizophrenia, and others. New to This Edition *Incorporates over a decade of technological and methodological innovations. *Chapter on theories and models of everyday functioning. *Chapters on naturalistic assessment, wearable sensors, ambulatory assessment, and virtual-reality-based tools. *Practical clinical implications are highlighted throughout.


Improving Health for Better Future Life: Strengthening from Basic Science to Clinical Research

Improving Health for Better Future Life: Strengthening from Basic Science to Clinical Research

Author: Muthmainah Muthmainah

Publisher: CRC Press

Published: 2023-12-29

Total Pages: 402

ISBN-13: 1003860176

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The proceedings of the 3rd International Conference on Health, Technology, and Life Science (ICO-HELICS 2022) shared ideas, pre-clinical and clinical research results, and literature review, on various aspects of medical science including heart disease, stroke, cancers, vaccines, infections, immunological disease, reproductive health, pharmacology and other health diseases. The proceedings aim to deliver new insights to the knowledge and practice of health workers and equip them in providing the best quality health care and clinical outcomes. As the idea of advanced clinical research originated from basic or fundamental research, it explores the life processes that are universal in their application to scientific knowledge. Therefore, these proceedings will also be of interest to academics, practitioners, health workers, and professionals involved in medical research.


HIV Neurology

HIV Neurology

Author: Bruce Brew

Publisher:

Published: 2001

Total Pages: 284

ISBN-13:

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This text provides a clinical framework for the diagnosis and management of more than seventy potential neurological complications that may occur in the HIV infected patient. The clinical framework is designed to be "user friendly" so that even the most inexperienced clinician should be able to arrive at the correct diagnosis. The neurological complications of HIV disease have considerably changed in the last decade. Not only have more opportunistic conditions been described but other complications arising from antiretroviral drugs such as lipodystrophy and accelerated atherosclerosis have become problematic. Moreover, the pattern of complications has altered. Diseases such as cerebral toxoplasmosis, AIDS dementia complex and primary central nervous system lymphoma are now becoming uncommon to rare while peripheral neuropathy is becoming increasingly common. In line with these changes, there have been very significant advances in the therapy of HIV disease in general and in neurological complications in particular. Patients with AIDS dementia complex now have a variety of antiretroviral and adjuvant drugs available to them in contrast to the situation only five years ago where therapy was confined to two antiretroviral drugs at best.


Global Virology I - Identifying and Investigating Viral Diseases

Global Virology I - Identifying and Investigating Viral Diseases

Author: Paul Shapshak

Publisher: Springer

Published: 2015-07-13

Total Pages: 847

ISBN-13: 1493924109

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This book provides trajectories and illustrations of viruses that have catapulted into the global arena (linked to humans, animals, and vectors) due to human behaviors in recent years, as well as viruses that have already shown expansion among humans, animals, and vectors just a few decades ago. Topics in the current book include: vaccines environmental impact emerging virus transmission Filovirus (Ebola) hemorrhagic fevers flaviviruses Dengue evasion papillomaviruses Hepatitis C Nipah virus giant viruses hantaviruses bunyaviruses encephalitides West Nile virus Zika virus XMRV henipaviruses human respiratory syncytial virus influenza A virus several aspects of HIV-1