Global Burden and Challenges of Melioidosis
Global Burden and Challenges of Melioidosis

Author: Direk Limmathurotsakul

Publisher: MDPI

Published: 2019-03-26

Total Pages: 272

ISBN-13: 303897742X

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This book is the definitive reference regarding the global status of melioidosis in 2018. Melioidosis is one of the most neglected tropical diseases (NTDs), so much so that it is not even included in the WHO list of NTDs. Yet modeling suggests that it kills more people worldwide every year than diseases that are much better known, such as leptospirosis and dengue. The reasons for this under-recognition are numerous, including the fact that it mainly affects the disadvantaged rural poor in areas that are poorly supplied with the diagnostic capability to make the diagnosis. In 22 separate articles, expert authors from around the world have summarized what is known about the burden of the disease in humans and animals and the presence of the causative bacterium in the environment in their countries or regions. They have also identified the main obstacles and challenges to establishing the true burden, and to ensure that patients receive accurate diagnosis and optimal care for this all too frequently fatal disease. Rather than focusing on the theoretical risk of the use of Burkholderia pseudomallei as a biological weapon, this book highlights its importance as a clear and present danger to global public health.

Sepsis Management in Resource-limited Settings
Sepsis Management in Resource-limited Settings

Author: Arjen M. Dondorp

Publisher: Springer

Published: 2019-02-08

Total Pages: 226

ISBN-13: 3030031438

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This book is open access under a CC BY 4.0 license. It constitutes a unique source of knowledge and guidance for all healthcare workers who care for patients with sepsis and septic shock in resource-limited settings. More than eighty percent of the worldwide deaths related to sepsis occur in resource-limited settings in low and middle-income countries. Current international sepsis guidelines cannot be implemented without adaptations towards these settings, mainly because of the difference in local resources and a different spectrum of infectious diseases causing sepsis. This prompted members of the Global Intensive Care working group of the European Society of Intensive Care Medicine (ESICM) and the Mahidol-Oxford Tropical Medicine Research Unit (MORU, Bangkok, Thailand) - among which the Editors – to develop with an international group of experts a comprehensive set of recommendations for the management of sepsis in resource-limited settings. Recommendations are based on both current scientific evidence and clinical experience of clinicians working in resource-limited settings. The book includes an overview chapter outlining the current challenges and future directions of sepsis management as well as general recommendations on the structure and organization of intensive care services in resource-limited settings. Specific recommendations on the recognition and management of patients with sepsis and septic shock in these settings are grouped into seven chapters. The book provides evidence-based practical guidance for doctors in low and middle income countries treating patients with sepsis, and highlights areas for further research and discussion.

Human Melioidosis
Human Melioidosis

Author: S. D. Puthucheary

Publisher: NUS Press

Published: 2002

Total Pages: 114

ISBN-13: 9789971692612

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Infectious diseases account for a third of all deaths in the developing world, yet the pathogens which affect specifically these predominantly poor people attract little attention. Melioidosis is a case in point. This book describes the epidemiology, pathology, pathophysiology, clinical features, diagnosis, management and prevention of an important infection that is little known outside Southeast Asia and Australia.

Manson's Tropical Diseases E-Book
Manson's Tropical Diseases E-Book

Author: Jeremy Farrar

Publisher: Elsevier Health Sciences

Published: 2023-07-14

Total Pages: 1638

ISBN-13: 0702079618

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For 125 years, physicians have relied on Manson's Tropical Diseases for a comprehensive clinical overview of this complex and fast-changing field. The fully revised 24th Edition, Dr. Jeremy Farrar, along with an internationally recognized editorial team, global contributors, and expert authors, delivers the latest coverage on parasitic and infectious diseases from around the world. From the difficult to diagnose to the difficult to treat, this highly readable, award-winning reference prepares you to effectively handle whatever your patients may have contracted. - Covers all of tropical medicine in a comprehensive manner, general medicine in the tropics, and non-clinical issues regarding public health and ethics. - Serves as an indispensable resource for physicians who treat patients with tropical diseases and/or will be travelling to the tropics, or who are teaching others in this area. - Contains a new section on 21st Century Drivers of Tropical Medicine, with chapters covering Poverty and Inequality, Public Health in Settings of Conflict and Political Instability, Climate Change, and Medical Product Quality and Public Health. - Includes all-new chapters on Surgery in the Topics, Yellow Fever, Systemic Mycoses, and COVID-19. - Covers key topics such as drug resistance; emerging and reemerging infections such as Zika, Ebola, and Chikungunya; novel diagnostics such as PCR-based methods; point-of care-tests such as ultrasound; public health in settings of conflict and political instability; and much more. - Differentiates approaches for resource-rich and resource-poor areas. - Includes reader-friendly features such as highlighted key information, convenient boxes and tables, extensive cross-referencing, and clinical management diagrams.

Methods in Vaccines and Molecular Therapeutics: 2022
Methods in Vaccines and Molecular Therapeutics: 2022

Author: Nargis Khan

Publisher: Frontiers Media SA

Published: 2024-02-26

Total Pages: 257

ISBN-13: 2832545289

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This Research Topic is part of the “Methods in Immunology” series. Please submit your article to the Research Topic that best suits the focus of your research. This series aims to highlight the latest experimental techniques and methods used to investigate fundamental questions in Immunology research, with a focus on Vaccines and Molecular Therapeutics. Review articles or opinions on methodologies or applications including the advantages and limitations of each are welcome. This Topic includes technologies and up-to-date methods which help advance science.

Inpatient Dermatology
Inpatient Dermatology

Author: Misha Rosenbach

Publisher: Springer

Published: 2018-11-03

Total Pages: 373

ISBN-13: 3319184490

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​​​ Inpatient Dermatology is a concise and portable resource that synthesizes the most essential material to help physicians with recognition, differential diagnosis, work-up, and treatment of dermatologic issues in the hospitalized patient. Complete with hundreds of clinical and pathologic images, this volume is both an inpatient dermatology atlas and a practical guide to day-one, initial work-up, and management plan for common and rare skin diseases that occur in the inpatient setting. Each chapter is a bulleted, easy-to-read reference that focuses on one specific inpatient dermatologic condition, with carefully curated clinical photographs and corresponding histopathologic images to aid readers in developing clinical-pathologic correlation for the dermatologic diseases encountered in the hospital. Before each subsection the editors share diagnostic pearls, explaining their approach to these challenging conditions. This book is structured to be useful to physicians, residents, and medical students. It spans dermatology, emergency medicine, internal medicine, infectious disease, and rheumatology. Inpatient Dermatology is the go-to guide for hospital-based skin diseases, making even the most complex inpatient dermatologic issues approachable and understandable for any clinician.

Disease Control Priorities, Third Edition (Volume 6)
Disease Control Priorities, Third Edition (Volume 6)

Author: King K. Holmes

Publisher: World Bank Publications

Published: 2017-11-06

Total Pages: 1027

ISBN-13: 1464805253

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Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Leptospira and Leptospirosis
Leptospira and Leptospirosis

Author: Ben Adler

Publisher: Springer

Published: 2014-11-11

Total Pages: 295

ISBN-13: 3662450593

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This volume covers all aspects of infection by pathogenic Leptospira species, the causative agents of the world’s most widespread zoonosis. Topics include aspects of human and animal leptospirosis as well as detailed analyses of our current knowledge of leptospiral structure and physiology, epidemiology, pathogenesis, genomics, immunity and vaccines. Updates are presented on leptospiral systematics, identification and diagnostics, as well as practical information on culture of Leptospira. Contact information is also provided for Leptospira reference centers. All chapters were written by experts in the field, providing an invaluable reference source for scientists, veterinarians, clinicians and all others with an interest in leptospirosis.

Handbook of Sepsis
Handbook of Sepsis

Author: W. Joost Wiersinga

Publisher: Springer

Published: 2018-04-13

Total Pages: 264

ISBN-13: 3319735063

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This practically oriented book provides an up-to-date overview of all significant aspects of the pathogenesis of sepsis and its management, including within the intensive care unit. Readers will find information on the involvement of the coagulation and endocrine systems during sepsis and on the use of biomarkers to diagnose sepsis and allow early intervention. International clinical practice guidelines for the management of sepsis are presented, and individual chapters focus on aspects such as fluid resuscitation, vasopressor therapy, response to multiorgan failure, antimicrobial therapy, and adjunctive immunotherapy. The closing section looks forward to the coming decade, discussing novel trial designs, sepsis in low- and middle-income countries, and emerging management approaches. The book is internatio nal in scope, with contributions from leading experts worldwide. It will be of value to residents and professionals/practitioners in the fields of infectious diseases and internal medicine, as well as to GPs and medical students.