Methods in Yeast Genetics and Genomics

Methods in Yeast Genetics and Genomics

Author: Maitreya J. Dunham

Publisher:

Published: 2015

Total Pages: 0

ISBN-13: 9781621821342

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Methods in Yeast Genetics is a course that has been offered annually at Cold Spring Harbor Laboratory for the last 45 years. This is an updated edition of the course manual, which provides a set of teaching experiments, along with protocols and recipes for the standard techniques and reagents used in the study of yeast biology. Since the last edition of the manual was published (2005), revolutionary advances in genomics, proteomics, and imaging technologies have had a significant impact on the field. The 11 experiments included in this manual provide a foundation of methods for any modern-day yeast lab. These methods emphasize combinations of classical and modern genetic approaches, including isolation and characterization of mutants, two-hybrid analysis, tetrad analysis, complementation, and recombination. Also covered are molecular genetic techniques for genome engineering. Additional experiments introduce fundamental techniques in yeast genomics, including both performance and interpretation of Synthetic Genetic Array analysis, multiplexed whole genome and barcode sequencing, and comparative genomic hybridization to DNA arrays. Comparative genomics is introduced using different yeast strains to study natural variation, evolution, and quantitative traits. This manual covers the full repertoire of genetic approaches needed to dissect complex biological problems in the yeast Saccharomyces cerevisiae.


Genetics

Genetics

Author: Chiyedza Small

Publisher:

Published: 2019-05-07

Total Pages:

ISBN-13: 9781524988159

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Genetics of Complex Human Diseases

Genetics of Complex Human Diseases

Author: Ammar Al-Chalabi

Publisher:

Published: 2009

Total Pages: 0

ISBN-13: 9780879698829

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Many human diseases – including Alzheimer's disease, schizophrenia, cancer, and cardiovascular disease – have complex genetics that require sophisticated analysis. Genetics of Complex Human Diseases: A Laboratory Manual& brings together the tools that geneticists use to find disease genes with the genetic concepts and statistical theories that underpin these research approaches. Topics covered include basic genetics and Mendelian inheritance, statistical methods, genetic epidemiology, linkage studies, transmission disequilibrium test analysis, variance components analysis, genome-wide association studies, copy-number variation, methods for high-throughput genotyping, the complexity of RNA editing, and genetic computer programs. The book's chapters, written by leading investigators in the field, blend practical information and reviews of each topic, providing both the how and the why of complex disease analysis. Genetics of Complex Human Diseasesis an important guide for anyone with an interest in human genetics or who uses genetic techniques in the study of diseases with complex inheritance.


A Short Course in Bacterial Genetics

A Short Course in Bacterial Genetics

Author: Jeffrey H. Miller

Publisher: CSHL Press

Published: 1992

Total Pages: 484

ISBN-13: 9780879693497

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University of California, Los Angeles. Introduction to bacterial genetics, including laboratory methods, for advanced students and beginning researchers. Handbook with plastic spiral-bound laboratory manual.


Methods in Yeast Genetics

Methods in Yeast Genetics

Author: David C. Amberg

Publisher: CSHL Press

Published: 2005

Total Pages: 250

ISBN-13: 0879697288

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"Methods in Yeast Genetics" is a course that has been offered annually at Cold Spring Harbor for the last 30 years. This provides a set of teaching experiments along with the protocols and recipes for the standard techniques and reagents used in the study of yeast biology.


The Human DNA Manual

The Human DNA Manual

Author: Dr. Melita Irving

Publisher: Haynes Publishing UK

Published: 2019-11-19

Total Pages: 0

ISBN-13: 9781785215940

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The Human DNA Manual aims to enlighten and entertain the genetically curious layperson on all aspects of our DNA and genetic code. An introductory section covers the basic concepts of genetics and debunks some of the confusion that stems from associated jargon. A history of DNA discovery explains the role of this molecule-of-inheritance and how it conveys the recipe for life, including how to extract your own DNA at home using every day household items. Discussing the relevance of DNA in the past, present and the future, author Melita Irving also covers the potential influence genes have in driving evolution; the concept of bringing back notable historical species from extinction, and the widespread role of DNA in everyday practices. Current issues, such as genetic conditions and the latest medical breakthroughs in detecting them, forensic science, gene therapy and sequencing are all clearly explained. Finally, the book looks at the future of genes and examine the impact DNA will have on the lives of the next generation — the epigenetics era and potentially heritable consequences of environmental exposures, the contribution of genetic engineering to a functioning society, the concept of gene editing in reproductive medicine, the slippery slope to a 'superhuman' race, and human cloning, as well as the potential for the development of new therapies using gene technology.


Genetics Manual

Genetics Manual

Author: G. P. R‚dei

Publisher: World Scientific

Published: 1998

Total Pages: 1150

ISBN-13: 9789810227807

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"Redei has created an outstanding compendium of genetics. Arranged as a dictionary, the book is almost an encyclopedic collection of terms & concepts ... The author has managed to define terms with appropriate mixtures of depth & detail for the researcher, along with clarity useful for the nonexpert." Choice, 1998


Methods in Yeast Genetics

Methods in Yeast Genetics

Author: Mark David Rose

Publisher:

Published: 1990

Total Pages: 212

ISBN-13:

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An intensive course in yeast genetics has been held at Cold Spring Harbor Laboratory for some years, and the course manual reflects its content and scope. Since its last publication in 1987, this manual's sequence of experiments has been extensively updated and expanded, and the protocols and append


Laboratory Manual of Genetics

Laboratory Manual of Genetics

Author: A. M. Winchester

Publisher: McGraw-Hill Science, Engineering & Mathematics

Published: 1995-12

Total Pages: 248

ISBN-13:

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Give your students the opportunity to apply the scientific method to "real" -not simulated- lab investigations in both classical and molecular genetics. It is appropriate for a range of genetics and molecular biology laboratory courses because it incorporates material spanning the areas of basic genetics, molecular genetics, and human genetics. Since the first edition, "Laboratory Manual of Genetics has been carefully constructed to be student-oriented.