Gene Therapy, An Issue of Hematology/Oncology Clinics of North America
Gene Therapy, An Issue of Hematology/Oncology Clinics of North America

Author: Daniel E. Bauer

Publisher: Elsevier Health Sciences

Published: 2017-09-27

Total Pages: 225

ISBN-13: 0323546692

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This issue of Hematology/Oncology Clinics will focus on Gene Therapy. Topics include, but are not limited to Historical Perspective and Current Renaissance, Integrating Vectors, Nonintegrating Vectors, Gene Editing, Conditioning Therapies for Autologous HSCT, Approaches to Immunodeficiency, Approaches to Hemoglobinopathy, Approaches to Hemophilia, Hematopoietic Gene Therapies for Neurologic and Metabolic Disease, Gene Therapy Approaches to HIV and other Infectious Diseases, HSC Approaches to Cancer, and Gene Modified T Cell Therapies for Cancer.

Gene Therapy, an Issue of Hematology/Oncology Clinics of North America
Gene Therapy, an Issue of Hematology/Oncology Clinics of North America

Author: Daniel E. Bauer

Publisher: Elsevier

Published: 2017-10-28

Total Pages:

ISBN-13: 9780323546683

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This issue of Hematology/Oncology Clinics will focus on Gene Therapy. Topics include, but are not limited to Historical Perspective and Current Renaissance, Integrating Vectors, Nonintegrating Vectors, Gene Editing, Conditioning Therapies for Autologous HSCT, Approaches to Immunodeficiency, Approaches to Hemoglobinopathy, Approaches to Hemophilia, Hematopoietic Gene Therapies for Neurologic and Metabolic Disease, Gene Therapy Approaches to HIV and other Infectious Diseases, HSC Approaches to Cancer, and Gene Modified T Cell Therapies for Cancer.

Gene-Based Therapies for Pediatric Blood Diseases, An Issue of Hematology/Oncology Clinics of North America, E-Book
Gene-Based Therapies for Pediatric Blood Diseases, An Issue of Hematology/Oncology Clinics of North America, E-Book

Author: Nirali N. Shah

Publisher: Elsevier Health Sciences

Published: 2022-07-19

Total Pages: 273

ISBN-13: 0323987761

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In this issue of Hematology/Oncology Clinics, guest editors Drs. Sung-Yun Pai and Nirali N. Shah bring their considerable expertise to the topic of Gene-Based Therapies for Pediatric Blood Diseases. Top experts in the field cover key topics such as CAR T-cell therapy: current status; engineered T cells; NK-cell therapy; hemoglobinopathies: beta-thalassemia, sickle cell disease; hemophilia A/B; primary immunodeficiencies; and more. - Contains 14 relevant, practice-oriented topics including the evolution of gene therapy; viral vectors in hematopoietic stem cell gene therapy; gene editing in hematopoietic stem cells; nonintegrating vectors and engineered capsids; regulatory aspects of gene therapy; and more. - Provides in-depth clinical reviews on gene-based therapies for pediatric blood diseases, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Pediatric Hematology, An Issue of Hematology/Oncology Clinics of North America
Pediatric Hematology, An Issue of Hematology/Oncology Clinics of North America

Author: Rachael Grace

Publisher: Elsevier Health Sciences

Published: 2019-05-05

Total Pages:

ISBN-13: 0323673341

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This issue of Hematology/Oncology Clinics, Guest Edited by Drs. Rachael Grace and Russell E. Ware, will focus on Pediatric Hematology. This issue is one of six selected for the year by the series Consulting Editors, George P. Canellos and H. Franklin Bunn. Topics include, but are not limited to, Rare Congenital Hemolytic Anemias, Sickle Cell, Thalassemia, Neutropenia and rare leukocyte disorders in children, Primary and Secondary Immune cytopenias, Disorders of Iron overload, Disorders of Iron metabolism, Approach to Hemophilia in a Changing Treatment Landscape, Von Willebrand disease, Inherited platelet disorders, Thrombosis, Diagnostic evaluation and medical approach to complications and treatment of vascular anomalies, New approaches and trials in Transfusion Medicine, and Updates in Neonatal Hematology.

Bladder Cancer, An Issue of Hematology/Oncology Clinics of North America, E-Book
Bladder Cancer, An Issue of Hematology/Oncology Clinics of North America, E-Book

Author: Guru P. Sonpavde

Publisher: Elsevier Health Sciences

Published: 2021-05-14

Total Pages: 241

ISBN-13: 0323764525

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This issue of Hematology/Oncology Clinics, Guest Edited by Dr. Guru P. Sonpavde, is devoted to Bladder Cancer. This issue is one of six selected each year by our series Consulting Editors, George P. Canellos and Edward J. Benz. Topics discussed in this important issue include: Epidemiology of bladder cancer, The molecular biology of bladder cancer and potential implications for therapy, Current therapy for metastatic urothelial carcinoma, Current perioperative therapy for muscle invasive urothelial carcinoma, Current therapy and emerging intravesical agents to treat non-muscle invasive bladder cancer, Diagnosis and staging of bladder and upper tract urothelial cancer, Surgery for bladder and upper tract urothelial cancer, Bladder conserving therapy for muscle invasive bladder cancer: opportunities to incorporate molecular profiling, Emerging immunotherapy for bladder cancer, Emerging targeted therapy for bladder cancer, Real world outcomes of patients with bladder cancer, Preclinical systems to develop bladder cancer therapeutics, Developing precision medicine for bladder cancer, and Future Directions in Bladder Cancer Treatment and Research.

Thalassemia, An Issue of Hematology/Oncology Clinics of North America, E-Book
Thalassemia, An Issue of Hematology/Oncology Clinics of North America, E-Book

Author: Edward J. BenzJr

Publisher: Elsevier Health Sciences

Published: 2023-03-16

Total Pages: 241

ISBN-13: 044318321X

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In this issue of Hematology/Oncology Clinics, guest editors Drs. Edward J. Benz, Jr. and Vijay G. Sankaran bring their considerable expertise to the topic of Thalassemia. Top experts in the field provide an overview of the history, epidemiology, pathogenic mechanisms, and clinical management of the thalassemia syndromes. - Contains 16 practice-oriented topics including molecular basis and genetic modifiers of thalassemia; fetal hemoglobin in thalassemia; clinical complications and their management; iron chelation in thalassemia; fertility and pregnancy in women with transfusion-dependent thalassemia; gene therapy and genome editing in thalassemia; emerging medical therapies for thalassemia; and more. - Provides in-depth clinical reviews on thalassemia, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Sickle Cell Syndromes, An Issue of Hematology/Oncology Clinics of North America, E-Book
Sickle Cell Syndromes, An Issue of Hematology/Oncology Clinics of North America, E-Book

Author: Sophie Lanzkron

Publisher: Elsevier Health Sciences

Published: 2022-11-20

Total Pages: 289

ISBN-13: 0323986641

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In this issue of Hematology/Oncology Clinics, guest editors Drs. Sophie Lanzkron and Jane Little bring their considerable expertise to the topic of Sickle Cell Syndromes. Top experts in the field cover key topics such as structural racism and impact on sickle cell disease (SCD); pathophysiology and biomarkers of SCD; genetic modifiers of SCD; allogeneic transplant and gene therapy: reproductive health; chronic pain; and more. - Contains 16 relevant, practice-oriented topics including innovative therapies, addressing challenging complications, novel science on mechanisms of disease; preventing cognitive decline in people with SCD; quality of life in SCD; and more. - Provides in-depth clinical reviews on sickle cell syndromes, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Upper Gastrointestinal Malignancies, An Issue of Hematology/Oncology Clinics of North America
Upper Gastrointestinal Malignancies, An Issue of Hematology/Oncology Clinics of North America

Author: Manish A. Shah

Publisher: Elsevier Health Sciences

Published: 2017-05-23

Total Pages: 201

ISBN-13: 0323530125

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This issue of Hematology/Oncology Clinics will focus on Upper Gastrointestinal Malignancies; specifically, articles on the following: Epidemiology / Genetics, H. pylori and the gastric microbiome in gastric cancer carcinogenesis; Barrett’s esophagus and esophageal cancer; Tumor Staging; Localized disease; Metastatic Disease; Immunotherapy Antiangiogenic therapy; and many more!

Thalassemia, An Issue of Hematology/Oncology Clinics of North America
Thalassemia, An Issue of Hematology/Oncology Clinics of North America

Author: Ali Taher

Publisher: Elsevier Health Sciences

Published: 2018-03-07

Total Pages: 209

ISBN-13: 0323583091

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This issue of Hematology/Oncology Clinics, edited by Dr. Ali Taher, focuses on Thalassemia. Topics include, but are not limited to, Molecular basis and genetic modifiers; Evolving spectrum of epidemiology; Clinical classification; Ineffective erythropoiesis, anemia and iron overload; Hypercoagulability and vascular disease; Clinical complications and their management; Transfusion and iron chelation therapy; Hematopoietic Stem Cell Transplantation in Thalassemia; Gene therapy and genome editing; Emerging therapies; Quality of life; Advances in understanding pathophysiology and treatment of fertility, pregnancy, and prenatal diagnosis in Thalassemia; and MRI for iron overload.