The Study of Gene Action
The Study of Gene Action

Author: Bruce Wallace

Publisher: Cornell University Press

Published: 1997

Total Pages: 276

ISBN-13: 9780801483400

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Although the physical nature of the gene was essentially clear by the late 1950s, the study of gene action, particularly during the development of higher organisms, is ongoing. Wallace and Falkinham explain how intimately progress has relied on technology. Initially limited to an examination of external features and subsequently to classical genetics and cytogenetic analyses, research was revolutionized by Watson and Crick's discovery of the double helix structure of DNA.

Gene Action
Gene Action

Author: Werner Maas

Publisher: Oxford University Press

Published: 2000-12-07

Total Pages: 177

ISBN-13: 0199748934

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This is the only book written by someone working in the field that deals with the history of gene action. As a college student, Werner Maas took a course in genetics in 1941 and wondered why so little was said about the biochemical action of genes in controlling the specific function of an organism. Just at that time, biochemists and geneticists began to investigate jointly the basis of gene action, especially in microorganisms. Thus, Maas was able to witness firsthand the spectacular developments that led in the next twenty-five years to a clear picture of the action of genes. The history of these remarkable discoveries is the core of this book. After 1965, building on insights gained from the work with microorganisms, studies of gene action turned to animals and plants and concentrated on processes not present in microorganisms, such as embryonic development, the role of genes in diseases, and the function of the nervous system. Because of the rapidity of technical advances made in handling genes, it has been possible to learn much about these complex processes. The last part of the book deals with these developments, which are ongoing parts of the history of gene action.

The Coat Colors of Mice
The Coat Colors of Mice

Author: W.K. Silvers

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 397

ISBN-13: 1461261643

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Many investigators seem to be fascinated by the coat colors of the mam mals with which they work. This seems to be the case particularly for those utilizing isogenic strains of mice, not only because such strains display wide ly different phenotypes, but because scientists, by definition, are an inquisi tive lot and it is sometimes difficult for the uninitiated to comprehend how such phenotypes are produced. This bewilderment becomes even more ap parent if the investigator happens to be involved in breeding studies and a number of attractively colored animals, quite different from the original stocks, appear. Thus I can recall numerous occasions when my colleagues, frequently working in areas completely unrelated to any aspect of genetics, have come to me with an attractively pigmented animal or, more likely, with a popUlation of segregating coat color types (usually because they have not tended their animals properly and have ended up with a cage full of F 2S displaying a number of different colors). How, they ask, do such colors come about? While in some cases it is easy to take chalk in hand and explain what has been going on (segregating) and why, in other cases it is virtually impossible. It is extremely difficult because while the interactions of many coat-color factors obey the simple laws of heredity and of predictable gene interactions, others do not.

Holland-Frei Cancer Medicine
Holland-Frei Cancer Medicine

Author: Robert C. Bast, Jr.

Publisher: John Wiley & Sons

Published: 2017-03-10

Total Pages: 2004

ISBN-13: 111900084X

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Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

The Selfish Gene
The Selfish Gene

Author: Richard Dawkins

Publisher: Oxford University Press, USA

Published: 1989

Total Pages: 372

ISBN-13: 9780192860927

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Science need not be dull and bogged down by jargon, as Richard Dawkins proves in this entertaining look at evolution. The themes he takes up are the concepts of altruistic and selfish behaviour; the genetical definition of selfish interest; the evolution of aggressive behaviour; kinshiptheory; sex ratio theory; reciprocal altruism; deceit; and the natural selection of sex differences. 'Should be read, can be read by almost anyone. It describes with great skill a new face of the theory of evolution.' W.D. Hamilton, Science

Epigenetic Mechanisms of Gene Regulation
Epigenetic Mechanisms of Gene Regulation

Author: Vincenzo E. A. Russo

Publisher:

Published: 1996

Total Pages: 716

ISBN-13:

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Many inheritable changes in gene function are not explained by changes in the DNA sequence. Such epigenetic mechanisms are known to influence gene function in most complex organisms and include effects such as transposon function, chromosome imprinting, yeast mating type switching and telomeric silencing. In recent years, epigenetic effects have become a major focus of research activity. This monograph, edited by three well-known biologists from different specialties, is the first to review and synthesize what is known about these effects across all species, particularly from a molecular perspective, and will be of interest to everyone in the fields of molecular biology and genetics.

Stress-Activated Protein Kinases
Stress-Activated Protein Kinases

Author: Francesc Posas

Publisher: Springer Science & Business Media

Published: 2008-01-24

Total Pages: 322

ISBN-13: 3540755691

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In this book leading researchers in the field discuss the state-of-the-art of many aspects of SAPK signaling in various systems from yeast to mammals. These include various chapters on regulatory mechanisms as well as the contribution of the SAPK signaling pathways to processes such as gene expression, metabolism, cell cycle regulation, immune responses and tumorigenesis. Written by international experts, the book will appeal to cell biologists and biochemists.

The Dependent Gene
The Dependent Gene

Author: David S. Moore

Publisher: Macmillan

Published: 2003-02-05

Total Pages: 324

ISBN-13: 9780805072808

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This book provides an analysis of the nature vs. nuture debate, arguing for an end to the 'either/or' nature of the discussions in favor of a recognition that environmental and genetic factors interact throughout life to form human traits.

The Search for the Gene
The Search for the Gene

Author: Bruce Wallace

Publisher: Cornell University Press

Published: 1992

Total Pages: 244

ISBN-13: 9780801499678

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From Gregor Mendel's experiments on garden peas to the mammoth Human Genome Project of today--how did we get where we are in the science of genetics? In this intriguing book, Bruce Wallace examines the concept of the gene and recounts the history of genetic research, providing a concise transition from genetics to modern molecular biology.