Nicholas Galanin
Nicholas Galanin

Author: Nicholas Galanin

Publisher:

Published: 2018-05-04

Total Pages: 144

ISBN-13: 9781732124103

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This publication spans the multiple generations and forms of media that inform Nicholas Galanin¿s ¿vessels of knowledge, culture and technology¿inherently political, generous, unflinching, and poetic.¿ He creates and speaks through multiple visual, audible, and tactile languages, a practice succinctly articulated through the introduction by artist Merritt Johnson, and further explored in conversation and critical analysis through scholars Negarra A. Kudumu and Erin Joyce. Galanin¿s practice includes numerous collaborations, including with his brother and fellow artist Jerrod Galanin under the moniker Leonard Getinthecar, through his participation in two artist collectives, Black Constellation, and Winter Count, and with the recently-announced group Indian Agent, along with Otis Calvin III, and Zak Dylan Wass¿their first album, Meditations in the Key of Red, was released in 2017.Through two- and three-dimensional works and time-based media, Galanin encourages reflection on cultural amnesia that actively obscures collective memory and acquisition of knowledge. Galanin¿s work has been exhibited extensively nationally and internationally. This is his first monograph.

Galanin
Galanin

Author: Tomas Hökfelt

Publisher: Springer Science & Business Media

Published: 2010-08-18

Total Pages: 285

ISBN-13: 3034602286

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Galanin is a neuropeptide found both in the central and peripheral nervous system. The 29-amino acid peptide (named after its N-terminal glycine and C-terminal alanine) was identified in 1983 by its C-terminal amidation. This 'reverse' approach, that is to discover a substance through a distinct chemical feature, and only subsequently to characterize its biological activity, was novel and has been successful in the identification of several other peptides. After the structure of galanin was determined in 1983, functional studies were performed with material purified from natural sources until the synthetic form of the peptide became available. Galanin can act as transmitter, modulator and trophic factor, and is involved in a number of physiological processes such as hormone secretion, cardiovascular mechanisms, feeding and cognition. This peptide may also be of significance for a number of pathological processes/disorders including pain, depression, Alzheimer's disease, epilepsy, addiction and cancer. This wide diversity of actions is mediated by three galanin receptor subtypes. The studies reviewed in this volume give a fairly complete overview of the spectrum of the biological actions and functions of galanin and its receptors and on possible therapeutic applications in a number of pathological conditions.

Never Forget
Never Forget

Author: Nicholas Galanin

Publisher:

Published: 2021-06

Total Pages: 48

ISBN-13: 9781735642314

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Nicholas Galanin's forthcoming artist's book is dedicated to a single work, Never Forget-. This piece, beyond the visual component, is a call to action regarding the Land Back movement to acquire legal title to Indigenous homelands for tribal communities in the United States.

Handbook of Biologically Active Peptides
Handbook of Biologically Active Peptides

Author: Abba Kastin

Publisher: Elsevier

Published: 2011-04-28

Total Pages: 1682

ISBN-13: 0080463797

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Peptides play a crucial role in many physiological processes including actions as neurotransmitters, hormones, and antibiotics. Research has shown their importance in such fields as neuroscience, immunology, pharmacology, and cell biology. The Handbook of Biologically Active Peptides presents, for the first time, this tremendous body of knowledge in the field of biologically active peptides in one single reference. The section editors and contributors represent some of the most sophisticated and distinguished scientists working in basic sciences and clinical medicine. The Handbook of Biologically Active Peptides is a definitive, all-encompassing reference that will be indispensable for individuals ranging from peptide researchers, to biochemists, cell and molecular biologists, neuroscientists, pharmacologists, and to endocrinologists. Chapters are designed to be a source for workers in the field and will enable researchers working in a specific area to examine other related areas with which they would not ordinarily be familiar.*Chapters are designed to be a source for workers in the field and will enable researchers working in a specific area to examine other related areas that they would not ordinarily be familiar.*Fascinating relationships described in the book include the presence of some peptides originally found in frog skin that persist in the human human and brain where they can affect food intake and obesity.

Encyclopedia of Molecular Pharmacology
Encyclopedia of Molecular Pharmacology

Author: Stefan Offermanns

Publisher: Springer Science & Business Media

Published: 2008-08-14

Total Pages: 1515

ISBN-13: 3540389164

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An essential text, this is a fully updated second edition of a classic, now in two volumes. It provides rapid access to information on molecular pharmacology for research scientists, clinicians and advanced students. With the A-Z format of over 2,000 entries, around 350 authors provide a complete reference to the area of molecular pharmacology. The book combines the knowledge of classic pharmacology with the more recent approach of the precise analysis of the molecular mechanisms by which drugs exert their effects. Short keyword entries define common acronyms, terms and phrases. In addition, detailed essays provide in-depth information on drugs, cellular processes, molecular targets, techniques, molecular mechanisms, and general principles.

Peptide Receptors
Peptide Receptors

Author: Remi Quirion

Publisher: Gulf Professional Publishing

Published: 2000

Total Pages: 442

ISBN-13: 0444505407

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Peptide Receptors Part I was published in 2000 (as volume 16 of the Handbook of Chemical Neuroanatomy series). This volume summarized current knowledge on the discrete anatomical distribution of ten families of neuropeptide receptors expressed in the mammalian CNS. Part II is its natural complement with chapters covering six additional families of neuropeptide receptors for ligands ranging from well known peptides such as the opioids and neurotensin to recently isolated ones like the orexins. As in the case of Part I, this volume integrates photomontages and maps of quantitative receptor autoradiography, in situ hybridization histochemistry and immunocytochemistry. Data derived from transgenic and knock-out animals are also summarized, helping to decipher the possible physiological and Pathophysiological role(s) of a given peptide family. Some chapters also review current knowledge on the profile of internalization of the neuropeptide-receptor complex, an area of intense research activities that should help to better understand mechanisms involved in desensitization and tachyphylaxis.

GnRH: The Master Molecule of Reproduction
GnRH: The Master Molecule of Reproduction

Author: Andrea C. Gore

Publisher: Springer Science & Business Media

Published: 2002-04-30

Total Pages: 360

ISBN-13: 9780792376811

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Gonadotropin-releasing hormone (GnRH) cells are the key regulators of reproductive function in all vertebrate organisms. The GnRH molecule is synthesized in a small number of neurons in rostral hypothalamic regions of the brain. In mammals, these neurons release the GnRH decapeptide into the portal capillary system leading to the anterior pituitary gland. There, GnRH causes the release of the gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn act upon the gonads to stimulate their maturation, and to cause synthesis of sex steroid hormones, estrogen, progesterone and testosterone. Although each of the levels of the hypothalamic-pituitary-gonadal axis is critical for reproductive function, GnRH neurons play the primary role in the control of reproductive maturation and adult reproductive function, and may even play a role in reproductive senescence. Since its discovery in 1970, there has been intense interest in GnRH-producing neurons, with more than 8000 papers and chapters in the last decade alone. Despite this activity of research in basic and clinical science, there has never been a book written specifically on GnRH neurons. GnRH: The Master Molecule of Reproduction aims to bring together the large and diverse literature of both laboratory and applied research that focuses on these unique cells. This book will provide basic background into reproductive neuroendocrinology, as well as specifics regarding the role of GnRH neurons in the control of reproduction. Students studying endocrinology, reproduction, neuroendocrinology or molecular endocrinology will benefit from this book. In addition, this book will take a multi-species approach which will be useful both to basic researchers as well as clinicians. Whenever possible, species differences and similarities will be presented, and if possible, studies on humans, or the clinical relevance of basic research findings to humans will be discussed (such as the treatment of reproductive disorders such as abnormalities in pubertal development, or infertility).

Encyclopedia of Neuroscience, Volume 1
Encyclopedia of Neuroscience, Volume 1

Author: Larry R. Squire

Publisher: Academic Press

Published: 2009-06-12

Total Pages: 12505

ISBN-13: 0080963935

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The Encyclopedia of the Neuroscience explores all areas of the discipline in its focused entries on a wide variety of topics in neurology, neurosurgery, psychiatry and other related areas of neuroscience. Each article is written by an expert in that specific domain and peer reviewed by the advisory board before acceptance into the encyclopedia. Each article contains a glossary, introduction, a reference section, and cross-references to other related encyclopedia articles. Written at a level suitable for university undergraduates, the breadth and depth of coverage will appeal beyond undergraduates to professionals and academics in related fields.

Drug Discovery and Evaluation: Pharmacological Assays
Drug Discovery and Evaluation: Pharmacological Assays

Author: Hans Vogel

Publisher: Springer Science & Business Media

Published: 2007-10-30

Total Pages: 2118

ISBN-13: 3540714200

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The new edition of this successful reference offers both cutting-edge and classic pharmacological methods. Thoroughly revised and expanded to two volumes, it offers an updated selection of the most frequently used assays for reliably detecting the pharmacological effects of potential drugs. Every chapter has been updated, and numerous assays have been added. Each of the more than 1,000 assays comprises a detailed protocol outlining purpose and rationale, and a critical assessment of the results and their pharmacological and clinical relevance.

Sensory Mechanisms of the Spinal Cord
Sensory Mechanisms of the Spinal Cord

Author: William D. Willis Jr.

Publisher: Springer Science & Business Media

Published: 2004-01-31

Total Pages: 620

ISBN-13: 9780306480331

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The third edition of this monograph continues to have the goal of providing an overview of current thought about the spinal cord mechanisms that are responsible for sensory processing. We hope that the book is of value to both basic and clinical neuroscientists. Several changes have been made in the presentation, as well as additions because of the research advances that have been made during the past decade. Chapters 3 and 4 in the previous edition have been subdivided, and now the morphology of primary afferent neu rons of the dorsal root ganglia is described in Chapter 3 and the chemical neuroanatomy 4. The description of the dorsal hom in the previous Chapter 4 of these neurons in Chapter is now included in Chapter 5, and the chemical neuroanatomy of the dorsal hom in Chapter 6. Furthermore, discussions of the descending control systems have now been of Chapter 12. consolidated at the end The authors would like to express their appreciation for the help provided by several individuals. R.E.C. wishes to acknowledge the many things he learned about primary afferent neurons from conversations with Dr S. N. Lawson. He also thanks Lyn Shilling for her assistance with the typing. WDW thanks Dr Nada Lawand for her critical reading of parts of the manuscript, Rosaline Leigh for help with the manuscript, and Griselda Gonzales for preparing the illustrations.