This practical book provides current and effective evaluation and treatment options currently available for the full spectrum of conditions affecting women. In easy to consume, bite-sized chapters, it ranges from diseases occurring during pregnancy and the perinatal period, through general gynecologic conditions from childhood to old age, gynecologic urology, oncology, reproductive medicine and family planning.
Conformal nets provide a mathematical model for conformal field theory. The authors define a notion of defect between conformal nets, formalizing the idea of an interaction between two conformal field theories. They introduce an operation of fusion of defects, and prove that the fusion of two defects is again a defect, provided the fusion occurs over a conformal net of finite index. There is a notion of sector (or bimodule) between two defects, and operations of horizontal and vertical fusion of such sectors. The authors' most difficult technical result is that the horizontal fusion of the vacuum sectors of two defects is isomorphic to the vacuum sector of the fused defect. Equipped with this isomorphism, they construct the basic interchange isomorphism between the horizontal fusion of two vertical fusions and the vertical fusion of two horizontal fusions of sectors.
As critically important as welding is to a wide spectrum of manufacturing, construction, and repair, it is not without its problems. Those dependent on welding know only too well how easy it is to find information on the host of available processes and on the essential metallurgy that can enable success, but how frustratingly difficult it can be to find guidance on solving problems that sooner or later arise with welding, welds, or weldments. Here for the first time is the book those that practice and/or depend upon welding have needed and awaited. A Practical Guide to Welding Solutions addresses the numerous technical and material-specific issues that can interfere with success. Renowned industrial and academic welding expert and prolific author and speaker Robert W. Messler, Jr. guides readers to the solutions they seek with a well-organized search based on how a problem manifests itself (i.e., as distortion, defect, or appearance), where it appears (i.e., in the fusion zone heat-affected zone, or base metal), or it certain materials or situations.
This volume of Current Topics in Membranes focuses on Membrane Fusion, beginning with fusion and fission of lipid bilayers, with reviews focused on hemifusion and dynamic remodeling of membranes catalyzed by dynamin. Other topics discussed include viral fusion, intracellular fusion, developmental cell fusion, and theoretical modeling.
EDITOR-IN-CHIEF: Clifford J. Rosen, M.D., Maine Medical Center Research Institute, Scarborough, Maine SENIOR ASSOCIATE EDITORS: Juliet E. Compston, M.D., FRCP, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom Jane B. Lian, Ph.D., University of Massachusetts Medical School, Worcester, Massachusetts This comprehensive yet concise handbook is an indispensable reference for the many clinicians who see patients with disorders of bone formation, metabolic bone diseases, or disorders of stone formation. It is also a crucial tool for researchers, students, and all other professionals working in the bone field. In a format designed for quick reference, it provides complete information on the symptoms, pathophysiology, diagnosis, and treatment of all common and rare bone and mineral disorders. New in this edition: detailed coverage of osteonecrosis of the jaw, more in-depth coverage of cancer and bone including new approaches to pathogenesis, diagnosis, and treatment; new approaches to anabolic therapy of osteoporosis; the latest research on Vitamin D; expanded coverage of international topics; more on the genetics of bone mass; and newer imaging techniques for the skeleton. In addition, this edition features a free, online-only appendix of medicines used to treat bone disorders and their availability around the world.
The advantages of composite materials include a high specific strength and stiffness, formability, and a comparative resistance to fatigue cracking and corrosion. However, not forsaking these advantages, composite materials are prone to a wide range of defects and damage that can significantly reduce the residual strength and stiffness of a structure or result in unfavorable load paths. Emphasizing defect identification and restitution, Defects and Damage in Composite Materials and Structures explains how defects and damage in composite materials and structures impact composite component performance. Providing ready access to an extensive, descriptive list of defects and damage types, this must-have reference: Examines defect criticality in composite structures Recommends repair actions to restore structural integrity Discusses failure modes and mechanisms of composites due to defects Reviews NDI processes for finding and identifying defects in composite materials Relating defect detection methods to defect type, the author merges his experience in the field of in-service activities for composite airframe maintenance and repair with indispensable reports and articles on defects and damage in advanced composite materials from the last 50 years.
We investigate the relationship between the algebra of tensor categories and the topology of framed 3-manifolds. On the one hand, tensor categories with cer-tain algebraic properties determine topological invariants. We prove that fusion categories of nonzero global dimension are 3-dualizable, and therefore provide 3-dimensional 3-framed local field theories. We also show that all finite tensor cat-egories are 2-dualizable, and yield categorified 2-dimensional 3-framed local field theories. On the other hand, topological properties of 3-framed manifolds deter-mine algebraic equations among functors of tensor categories. We show that the 1-dimensional loop bordism, which exhibits a single full rotation, acts as the double dual autofunctor of a tensor category. We prove that the 2-dimensional belt-trick bordism, which unravels a double rotation, operates on any finite tensor category, and therefore supplies a trivialization of the quadruple dual. This approach pro-duces a quadruple-dual theorem for suitably dualizable objects in any symmetric monoidal 3-category. There is furthermore a correspondence between algebraic structures on tensor categories and homotopy fixed point structures, which in turn provide structured field theories; we describe the expected connection between piv-otal tensor categories and combed fixed point structures, and between spherical tensor categories and oriented fixed point structures.
Infectious fungal diseases continue to take their toll in terms of human suffering and enormous economic losses. Invasive infections by opportunistic fungal pathogens are a major cause of morbidity and mortality in immuno-compromised individuals. At the same time, plant pathogenic fungi have devastating effects on crop production and human health. New strategies for antifungal control are required to meet the challenges posed by these agents, and such approaches can only be developed through the identification of novel biochemical and molecular targets. However, in contrast to bacterial pathogens, fungi display a wealth of “lifestyles” and modes of infection. This diversity makes it extremely difficult to identify individual, evolutionarily conserved virulence determinants and represents a major stumbling block in the search for common antifungal targets. In order to activate the infection programme, all fungal pathogens must undergo appropriate developmental transitions that involve cellular differentiation and the introduction of a new morphogenetic programme. How growth, cell cycle progression and morphogenesis are co-ordinately regulated during development has been an active area of research in fungal model systems such as budding and fission yeast. By contrast, we have only limited knowledge of how these developmental processes shape fungal pathogenicity, or of the role of the cell cycle and morphogenesis regulators as true virulence factors. This book combines state-of-the-art expertise from diverse pathogen model systems to update our current understanding of the regulation of fungal morphogenesis as a key determinant of pathogenicity in fungi.
