Quantitative Fundamentals of Molecular and Cellular Bioengineering

Quantitative Fundamentals of Molecular and Cellular Bioengineering

Author: K. Dane Wittrup

Publisher: MIT Press

Published: 2020-01-07

Total Pages: 593

ISBN-13: 0262042657

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A comprehensive presentation of essential topics for biological engineers, focusing on the development and application of dynamic models of biomolecular and cellular phenomena. This book describes the fundamental molecular and cellular events responsible for biological function, develops models to study biomolecular and cellular phenomena, and shows, with examples, how models are applied in the design and interpretation of experiments on biological systems. Integrating molecular cell biology with quantitative engineering analysis and design, it is the first textbook to offer a comprehensive presentation of these essential topics for chemical and biological engineering. The book systematically develops the concepts necessary to understand and study complex biological phenomena, moving from the simplest elements at the smallest scale and progressively adding complexity at the cellular organizational level, focusing on experimental testing of mechanistic hypotheses. After introducing the motivations for formulation of mathematical rate process models in biology, the text goes on to cover such topics as noncovalent binding interactions; quantitative descriptions of the transient, steady state, and equilibrium interactions of proteins and their ligands; enzyme kinetics; gene expression and protein trafficking; network dynamics; quantitative descriptions of growth dynamics; coupled transport and reaction; and discrete stochastic processes. The textbook is intended for advanced undergraduate and graduate courses in chemical engineering and bioengineering, and has been developed by the authors for classes they teach at MIT and the University of Minnesota.


Current Developments in Biotechnology and Bioengineering

Current Developments in Biotechnology and Bioengineering

Author: Ashok Pandey

Publisher: Elsevier

Published: 2017-09-12

Total Pages: 480

ISBN-13: 0444639918

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Current Developments in Biotechnology and Bioengineering: Current Advances in Solid-State Fermentation provides knowledge and information on solid-state fermentation involving the basics of microbiology, biochemistry, molecular biology, genetics and principles of genetic engineering, metabolic engineering and biochemical engineering. This volume of the series is on Solid-State fermentation (SSF), which would cover the basic and applied aspects of SSF processes, including engineering aspects such as design of bioreactors in SSF. The book offers a pool of knowledge on biochemical and microbiological aspects as well as chemical and biological engineering aspects of SSF to provide an integrated knowledge and version to the readers. - Provides state-of-the-art information on basic and fundamental principles of solid-state fermentation - Includes key features for the education and understanding of biotechnology education and R&D, in particular on SSF - Lists fermentation methods for the production of a wide variety of enzymes and metabolites - Provides examples of the various industrial applications of enzymes in solid state fermentation


Enzymatic Fuel Cells

Enzymatic Fuel Cells

Author: Heather R. Luckarift

Publisher: John Wiley & Sons

Published: 2014-05-27

Total Pages: 516

ISBN-13: 1118369238

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Summarizes research encompassing all of the aspects required to understand, fabricate and integrate enzymatic fuel cells Contributions span the fields of bio-electrochemistry and biological fuel cell research Teaches the reader to optimize fuel cell performance to achieve long-term operation and realize commercial applicability Introduces the reader to the scientific aspects of bioelectrochemistry including electrical wiring of enzymes and charge transfer in enzyme fuel cell electrodes Covers unique engineering problems of enzyme fuel cells such as design and optimization


Fundamentals of Enzymology

Fundamentals of Enzymology

Author: G. P. Royer

Publisher: John Wiley & Sons

Published: 1982-02-04

Total Pages: 256

ISBN-13:

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A balanced, intermediate treatise in enzymology that goes beyond the general biochemistry text. Presents principles and applications of enzyme catalysis.


Principles of Fermentation Technology

Principles of Fermentation Technology

Author: Peter F Stanbury

Publisher: Butterworth-Heinemann

Published: 2016-08-31

Total Pages: 826

ISBN-13: 0444634088

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The successful structure of the previous edition of Principles of Fermentation Technology has been retained in this third edition, which covers the key component parts of a fermentation process including growth kinetics, strain isolation and improvement, inocula development, fermentation media, fermenter design and operation, product recovery, and the environmental impact of processes. This accurate and accessible third edition recognizes the increased importance of animal cell culture, the impact of the post-genomics era on applied science and the huge contribution that heterologous protein production now makes to the success of the pharmaceutical industry. This title is ideally suited for both newcomers to the industry and established workers as it provides essential and fundamental information on fermentation in a methodical, logical fashion. Stanbury, Whitaker and Hall have integrated the biological and engineering aspects of fermentation to make the content accessible to members of both disciplines with a focus on the practical application of theory. This text collates all the fermentation fundamentals into one concise reference, making it a valuable resource for fermentation scientists, as well as those studying in the field. - Retains its successful structure and covers all components of the fermentation process - Integrates the biological and engineering aspects of fermentation to discuss the most recent developments and advancements in the field - Written in a style accessible to readers from either a biological or engineering background with each chapter supported by an extensive bibliography


Comprehensive Biotechnology

Comprehensive Biotechnology

Author:

Publisher: Newnes

Published: 2011-08-26

Total Pages: 5304

ISBN-13: 0080885047

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The second edition of Comprehensive Biotechnology, Six Volume Set continues the tradition of the first inclusive work on this dynamic field with up-to-date and essential entries on the principles and practice of biotechnology. The integration of the latest relevant science and industry practice with fundamental biotechnology concepts is presented with entries from internationally recognized world leaders in their given fields. With two volumes covering basic fundamentals, and four volumes of applications, from environmental biotechnology and safety to medical biotechnology and healthcare, this work serves the needs of newcomers as well as established experts combining the latest relevant science and industry practice in a manageable format. It is a multi-authored work, written by experts and vetted by a prestigious advisory board and group of volume editors who are biotechnology innovators and educators with international influence. All six volumes are published at the same time, not as a series; this is not a conventional encyclopedia but a symbiotic integration of brief articles on established topics and longer chapters on new emerging areas. Hyperlinks provide sources of extensive additional related information; material authored and edited by world-renown experts in all aspects of the broad multidisciplinary field of biotechnology Scope and nature of the work are vetted by a prestigious International Advisory Board including three Nobel laureates Each article carries a glossary and a professional summary of the authors indicating their appropriate credentials An extensive index for the entire publication gives a complete list of the many topics treated in the increasingly expanding field


Hydrogels in Medicine and Pharmacy

Hydrogels in Medicine and Pharmacy

Author: Nikolaos A. Peppas

Publisher: CRC Press

Published: 2019-08-15

Total Pages: 191

ISBN-13: 1000693864

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First Published in 1986, this book offers a full, comprehensive guide to the application of hydrogels in medicine. Carefully compiled and filled with a vast repertoire of notes, diagrams, and references this book serves as a useful reference for students of medicine and other practitioners in their respective fields.


Handbook of Cellulosic Ethanol

Handbook of Cellulosic Ethanol

Author: Ananda S. Amarasekara

Publisher: John Wiley & Sons

Published: 2013-12-17

Total Pages: 608

ISBN-13: 1118878426

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Comprehensive coverage on the growing science and technologyof producing ethanol from the world's abundant cellulosicbiomass The inevitable decline in petroleum reserves and its impact ongasoline prices, combined with climate change concerns, havecontributed to current interest in renewable fuels. Bioethanol isthe most successful renewable transport fuel—with corn andsugarcane ethanol currently in wide use as blend-in fuels in theUnited States, Brazil, and a few other countries. However, thereare a number of major drawbacks in these first-generation biofuels,such as their effect on food prices, net energy balance, and poorgreenhouse gas mitigation. Alternatively, cellulosic ethanol can beproduced from abundant lignocellulosic biomass forms such asagricultural or municipal wastes, forest residues, fast growingtrees, or grasses grown in marginal lands, and should be produciblein substantial amounts to meet growing global energy demand. The Handbook of Cellulosic Ethanol covers all aspects ofthis new and vital alternative fuel source, providing readers withthe background, scientific theory, and recent research progress inproducing cellulosic ethanol via different biochemical routes, aswell as future directions. The seventeen chapters includeinformation on: Advantages of cellulosic ethanol over first-generation ethanolas a transportation fuel Various biomass feedstocks that can be used to make cellulosicethanol Details of the aqueous phase or cellulolysis route,pretreatment, enzyme or acid saccharification, fermentation,simultaneous saccharification fermentation, consolidatedbioprocessing, genetically modified microorganisms, and yeasts Details of the syngas fermentation or thermochemical route,gasifiers, syngas cleaning, microorganisms for syngas fermentation,and chemical catalysts for syngas-to-ethanol conversion Distillation and dehydration to fuel-grade ethanol Techno-economical aspects and the future of cellulosicethanol Readership Chemical engineers, chemists, and technicians working onrenewable energy and fuels in industry, research institutions, anduniversities. The Handbook can also be used by studentsinterested in biofuels and renewable energy issues.