An integrated textbook of medical neuroscience, this book coherently presents the anatomy, physiology, and biochemistry of the human nervous system. The neuroanatomy is presented in a way that is integrated with a modern presentation of cellular neurophysiological systems, neuroscience, and cellular, molecular, and developmental neuroscience. Clinical correlations are provided wherever appropriate.
The late E. Roy John is considered the pioneer in the field of neurometrics – the science of measuring the underlying organization of the brain’s electrical activity. Volume 1, co-authored by Robert W. Thatcher, and Volume 2 both originally published in 1977, were among the first books this field. Volume 3, written by colleague Thalía Harmony, followed in 1984. The field expanded significantly in the 1990s and thousands of articles have subsequently been published. Available together for the first time these 3 volumes were important foundational works for the fields of quantitative electrophysiology and neurometrics.
A new edition of the essential resource on using functional neuroimaging techniques to study the neural basis of cognition, revised with the student in mind; thoroughly updated, with new chapters on fMRI physics, skill learning, emotion and social cognition, and other topics. This essential resource on neuroimaging provides an accessible and user-friendly introduction to the field written by leading researchers. The book describes theoretical and methodological developments in the use of functional neuroimaging techniques to study the neural basis of cognition, from early scientific efforts to link brain and behavior to the latest applications of fMRI and PET methods. The core of the book covers fMRI and PET studies in specific domains: attention, skill learning, semantic memory, language, episodic memory, working memory, and executive functions. By introducing a technique within the description of a domain, the book offers a clear explanation of the process while highlighting its biological context. The emphasis on readability makes Handbook of Functional Neuroimaging of Cognition ideal for classroom use in advanced undergraduate and graduate courses in cognitive neuroscience. This second edition has been completely updated to reflect new developments in the field, with existing chapters rewritten and new chapters added to each section. The section on history and methods now includes a chapter on the crucial topic of the physics of functional neuroimaging; the chapters on skill learning and executive functions are new to the domain section; and chapters on childhood development and emotion and social cognition have been added to the section on developmental, social, and clinical applications. The color insert has been increased in size, enhancing the visual display of representative findings. Contributors Todd S. Braver, Jeffrey Browndyke, Roberto Cabeza, B.J. Casey, Jody Culham, Clayton E. Curtis, Mark D'Esposito, Sander Daselaar, Lila Davachi, Ian Dobbins, Karl J. Friston, Barry Giesbrecht, Todd C. Handy, Joseph B. Hopfinger, Scott A. Huettel, Irene P. Kan, Alan Kingstone, Eleni Kotsoni, Kevin S. LaBar, George R. Mangun, Gregory McCarthy, Uta Noppeney, Robyn T. Oliver, Elizabeth A. Phelps, Russel A. Poldrack, Cathy J. Price, Marcus E. Raichle, Hannes Ruge, Gaia Scerif, Allen W. Song, Sharon L. Thompson-Schill, Daniel T. Willingham, Richard J.S. Wise
This updated second edition provides the state of the art perspective of the theory, practice and application of modern non-invasive imaging methods employed in exploring the structural and functional architecture of the normal and diseased human brain. Like the successful first edition, it is written by members of the Functional Imaging Laboratory - the Wellcome Trust funded London lab that has contributed much to the development of brain imaging methods and their application in the last decade. This book should excite and intrigue anyone interested in the new facts about the brain gained from neuroimaging and also those who wish to participate in this area of brain science.* Represents an almost entirely new book from 1st edition, covering the rapid advances in methods and in understanding of how human brains are organized* Reviews major advances in cognition, perception, emotion and action* Introduces novel experimental designs and analytical techniques made possible with fMRI, including event-related designs and non-linear analysis
Modern neuroscience research is inherently multidisciplinary, with a wide variety of cutting edge new techniques to explore multiple levels of investigation. This Third Edition of Guide to Research Techniques in Neuroscience provides a comprehensive overview of classical and cutting edge methods including their utility, limitations, and how data are presented in the literature. This book can be used as an introduction to neuroscience techniques for anyone new to the field or as a reference for any neuroscientist while reading papers or attending talks. - Nearly 200 updated full-color illustrations to clearly convey the theory and practice of neuroscience methods - Expands on techniques from previous editions and covers many new techniques including in vivo calcium imaging, fiber photometry, RNA-Seq, brain spheroids, CRISPR-Cas9 genome editing, and more - Clear, straightforward explanations of each technique for anyone new to the field - A broad scope of methods, from noninvasive brain imaging in human subjects, to electrophysiology in animal models, to recombinant DNA technology in test tubes, to transfection of neurons in cell culture - Detailed recommendations on where to find protocols and other resources for specific techniques - "Walk-through" boxes that guide readers through experiments step-by-step
Functional training develops the attributes and abilities required to perform tasks, skills and activities useful and relevant to daily life. Functional Exercise and Rehabilitation serves as an accessible and visual guide providing the essentials of therapeutic exercise and rehabilitation, including mobilization, stabilization and myofascial release. This book begins by explaining functional training and the foundation of the STRIVE approach. Chapter 2 introduces functional anatomy and Chapter 3 explains the fundamentals of neuroscience. The final chapters discuss the STRIVE principles and apply them to exercise, program design and injury recovery. Each chapter includes key point boxes, illustrations and photos of exercises discussed. Written by an exercise specialist and osteopath, this practical guide is presented in an easy-to-read style. Functional Exercise and Rehabilitation is essential reading for all health professionals, sports therapists and trainers involved in exercise prescription.
Functional Neuromarkers for Psychiatry explores recent advances in neuroscience that have allowed scientists to discover functional neuromarkers of psychiatric disorders. These neuromarkers include brain activation patterns seen via fMRI, PET, qEEG, and ERPs. The book examines these neuromarkers in detail—what to look for, how to use them in clinical practice, and the promise they provide toward early detection, prevention, and personalized treatment of mental disorders. The neuromarkers identified in this book have a diagnostic sensitivity and specificity higher than 80%. They are reliable, reproducible, inexpensive to measure, noninvasive, and have been confirmed by at least two independent studies. The book focuses primarily on the analysis of EEG and ERPs. It elucidates the neuronal mechanisms that generate EEG spontaneous rhythms and explores the functional meaning of ERP components in cognitive tasks. The functional neuromarkers for ADHD, schizophrenia, and obsessive-compulsive disorder are reviewed in detail. The book highlights how to use these functional neuromarkers for diagnosis, personalized neurotherapy, and monitoring treatment results. - Identifies specific brain activation patterns that are neuromarkers for psychiatric disorders - Includes neuromarkers as seen via fMRI, PET, qEEG, and ERPs - Addresses neuromarkers for ADHD, schizophrenia, and OCD in detail - Provides information on using neuromarkers for diagnosis and/or personalized treatment
Functional Neurology utilizes our understanding of how the nervous system works in the treatment of a variety of clinical conditions. Fuctional Neurology for Practitioners of Manual Medicine takes the reader from the embryonic beginnings of the nervous system, through the biochemistry of receptor activation and on to the functional systems of the nervous system. Both the student and the clinician will find this text a valuable source of information and clinical guidance in the application of detailed neurological principles to their practice. Concepts, relationships and scientific mechanisms of the nervous system function are covered, and this aids the practitioner in developing their clinical approach to a wide variety of patient presentations. This text explores the neurological impact of the application of functional neurological principles, using a detailed clinical approach supported by clinical case studies. The text is fully referenced, which allows the reader to immediately apply the concepts to practice situations. New for this edition are new chapters on pain (including headache) and theoretical evidence, plus extensive electronic resources supporting the text. - Utilizes our understanding of how the nervous system works in the treatment of a variety of clinical conditions - Demystifies the clinical results seen in the practice of Functional Neurology and scientifically validates its clinical success - Addresses function rather than pathology, allowing the reader to gain a firm understanding of the neurological processes seen in health and disease - Contains clinical cases which are designed to be read and answered before starting the chapter to allow the reader to gauge their current state of knowledge - 'Quick Facts' introduce new concepts or allow rapid review of information already presented in the text in a brief and succinct manner - Contains a detailed overview of the concepts relating to our understanding of the development of emotion to demonstrate the link between physical health and the mind - Contains abundant references to support controversial concepts - Contains new chapters on theoretical evidence and the management of pain (including headache) - Contains a wide range of additional case studies, 'clinical conundrums' and key questions and answers for each topic - Bonus DVD contains fully searchable text, a downloadable image bank, brain dissection and video clips of the manipulative techniques and examination procedures found within the volume plus 200 multiple choice questions
The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. Each volume in the series consists of review style articles that average 15-20pp and feature numerous illustrations and full references. Volume 3 offers 40 high level articles devoted mainly to anatomical and functional development of neural circuits and neural systems, as well as those that address neurodevelopmental disorders in humans and experimental organisms. Series offers 144 articles for 2904 full color pages addressing ways in which the nervous system and its components develop Features leading experts in various subfields as Section Editors and article Authors All articles peer reviewed by Section Editors to ensure accuracy, thoroughness, and scholarship Volume 3 sections include coverage of: mechanisms that control the assembly of neural circuits in specific regions of the nervous system, multiple aspects of cognitive development, and disorders of the nervous system arising through defects in neural development
This book is a practical manual for clinical practitioners seeking to take an interdisciplinary and multidisciplinary approach to the diagnosis and management of functional movement disorder (FMD). It discusses case vignettes, reviews the diagnostic approach, provides an update on available treatments, highlights clinical pearls and details references for further reading. Organized into three parts, the book begins with a framework for conceptualizing FMD - including its historical context, the biopsychosocial model and an integrated neurologic-psychiatric perspective towards overcoming mind-body dualism. Part II then provides a comprehensive overview of different FMD presentations including tremor, dystonia, gait disorders, and limb weakness, as well as common non-motor issues such as pain and cognitive symptoms. The book concludes with chapters on updated practices in delivering the diagnosis, working with patients and care partners to achieve shared understanding of a complex condition, as well as an overview of evidence-based and evolving treatments. Supplemented with high-quality patient videos, Functional Movement Disorder is written for practicing neurologists, psychiatrists, psychologists, allied mental health professionals, and rehabilitation experts with an interest in learning more about diagnosis and management of FMD.
