Proton Pump Inhibitors: A Balanced View

Proton Pump Inhibitors: A Balanced View

Author: T. Chiba

Publisher: Karger Medical and Scientific Publishers

Published: 2013-09-23

Total Pages: 130

ISBN-13: 3318024155

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The discovery of proton pump inhibitors (PPIs) and their development over the years has dramatically changed the management of acid-related diseases. Today, the therapeutic domain of PPIs ranges from relief of symptoms to cure of mucosal lesions in the upper gastrointestinal tract. PPIs are among the most widely sold drugs in the world and are now even available as over-the-counter medication. This publication presents the experience of the last 25 years during which PPIs have become of enormous value in gastroenterology. The authors provide an update on a variety of subjects, starting with an introduction to the discovery and development of PPIs. This is followed by chapters on pharmacokinetics, pharmacodynamics and pharmacogenetics, gastroesophageal reflux disease, gastroprotection, Helicobacter pylori eradication treatment, peptic ulcer disease, functional dyspepsia, acid suppression in exocrine pancreatic insufficiency, and gastrointestinal and systemic side effects. Readers who are interested in a current overview of PPIs and their various applications will find this book of great value.


Interventional and Therapeutic Gastrointestinal Endoscopy

Interventional and Therapeutic Gastrointestinal Endoscopy

Author: K. Mönkemüller

Publisher: Karger Medical and Scientific Publishers

Published: 2009-11-13

Total Pages: 560

ISBN-13: 3805593090

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The aim of this book is to present a concise yet instructive overview of the most common interventional and therapeutic gastrointestinal endoscopic procedures. Although there exists a large amount of literature dealing with therapeutic endoscopy, this publication stands out for several reasons: To begin with, it has been written by a highly selected group of international experts who contribute their own tried and tested tips and tricks. The various techniques are described in a homogeneous fashion, making it easy for the endoscopist to single out the important aspects for his or her own practice. Moreover, the data presented follows evidence-based guidelines, but does not inundate the reader with confusing facts and numbers. Finally, the book is illustrated like an atlas, featuring real-life pictures enhanced by explanatory drawings and algorithms.


Frontiers in Oncology: Quarterly Highlights. Quarter 1 2019

Frontiers in Oncology: Quarterly Highlights. Quarter 1 2019

Author: Giuseppe Giaccone

Publisher: Frontiers Media SA

Published: 2019-07-01

Total Pages: 213

ISBN-13: 288945939X

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Foreword from the Field Chief Editor, Giuseppe Giaccone Once again Frontiers in Oncology has started the year on a positive note, breaking previous records for submissions and publications, as well as the number of Research Topic article collections posted. The journal continues to grow in size, adding an 18th section focusing on Cancer Metabolism, led by Michael Lisanti and Ubaldo Martinez-Outschoorn, and has brought on a total of five new Chief Editors. Here, introducing Frontiers in Oncology: Quarterly Highlights, we feature a collection of carefully selected articles published during the first quarter of 2019 across the different sections. With a record number of papers to choose from, the papers enclosed in this Special Edition highlight some of the recent advances across the different disciplines. With an array of papers looking at everything from translational research to association studies and clinical trial results, Frontiers in Oncology continues to publish high-quality research from researchers around the world. Many of the recently posted Research Topics in the journal focus on early diagnosis and prevention, as well as the importance of survivorship studies and outcomes of cancer treatment. Consideration of such aspects of cancer research and treatment is pivotal in the global effort towards increased survival rates and improved quality of life. With ASCO 2019 marking the end of Q1 and the transition into Q2, the journal looks forward to the rest of the year, and continuing to play an active role in the research community. Giuseppe Giaccone


Feline Gastroenterology

Feline Gastroenterology

Author: Fabio Procoli

Publisher: Edra

Published: 2021-10-29T00:00:00+02:00

Total Pages: 977

ISBN-13: 8821452344

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The aim of this book is to focus on problems unique to the feline alimentary tract in comparison to dogs and to discuss them in detail, but also to highlight areas where knowledge is lacking or can only be derived from comparison with other companion animal species or humans. Instead of being a comprehensive work of “all things GI” in the cat, this book aims to shine a light on topics that are novel, such as the microbiome or probiotics, and might not have been covered by other standard textbooks. This book focuses on “a medic’s perspective” on feline alimentary tract health, which starts with considering differential diagnoses in a structured way based on the most common clinical signs. It also includes the invaluable input from other specialties we so often draw on in clinical practice, namely laboratory diagnostics, diagnostic imaging, clinical pathology and histopathology, and nutrition, which can be a particular challenge in cats. It also covers feline-specific infectious and neoplastic diseases. Appropriate methods for retrieving adequate samples from organs of the alimentary tract in cats are discussed, and a particular focus on the challenges of differentiating inflammation from neoplasia is present in several chapters. Extra materials and videos are available on http://felinegastroenterology.edizioniedra.com


Drug Repositioning: Current Advances and Future Perspectives

Drug Repositioning: Current Advances and Future Perspectives

Author: Yuhei Nishimura

Publisher: Frontiers Media SA

Published: 2019-01-11

Total Pages: 153

ISBN-13: 288945696X

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Drug repositioning is the process of identifying new indications for existing drugs. At present, the conventional de novo drug discovery process requires an average of about 14 years and US$2.5 billion to approve and launch a drug. Drug repositioning can reduce the time and cost of this process because it takes advantage of drugs already in clinical use for other indications or drugs that have cleared phase I safety trials but have failed to show efficacy in the intended diseases. Historically, drug repositioning has been realized through serendipitous clinical observations or improved understanding of disease mechanisms. However, recent technological advances have enabled a more systematic approach to drug repositioning. This eBook collects 16 articles from 112 authors, providing readers with current advances and future perspectives of drug repositioning.


Current Catalog

Current Catalog

Author: National Library of Medicine (U.S.)

Publisher:

Published:

Total Pages: 1712

ISBN-13:

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First multi-year cumulation covers six years: 1965-70.