Formation of Intracardiac Electrograms under Physiological and Pathological Conditions
Formation of Intracardiac Electrograms under Physiological and Pathological Conditions

Author: Keller, Matthias

Publisher: KIT Scientific Publishing

Published: 2014-09-09

Total Pages: 264

ISBN-13: 3731502283

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This work presents methods to advance electrophysiological simulations of intracardiac electrograms (IEGM). An experimental setup is introduced, which combines electrical measurements of extracellular potentials with a method for optical acquisition of the transmembrane voltage in-vitro. Thereby, intracardiac electrograms can be recorded under defined conditions. Using experimental and clinical signals, detailed simulations of IEGMs are parametrized, which can support clinical diagnosis.

Characterizing Cardiac Electrophysiology during Radiofrequency Ablation : An Integrative Ex vivo, In silico, and In vivo Approach
Characterizing Cardiac Electrophysiology during Radiofrequency Ablation : An Integrative Ex vivo, In silico, and In vivo Approach

Author: Pollnow, Stefan

Publisher: KIT Scientific Publishing

Published: 2019-04-23

Total Pages: 296

ISBN-13: 3731508869

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Catheter ablation is a major treatment for atrial tachycardias. Hereby, the precise monitoring of the lesion formation is an important success factor. This book presents computational, wet-lab, and clinical studies with the aim of evaluating the signal characteristics of the intracardiac electrograms (IEGMs) recorded around ablation lesions from different perspectives. The detailed analysis of the IEGMs can optimize the description of durable and complex lesions during the ablation procedure.

Formation of Intracardiac Electrograms Under Physiological and Pathological Conditions
Formation of Intracardiac Electrograms Under Physiological and Pathological Conditions

Author: Matthias Keller

Publisher:

Published: 2020-10-09

Total Pages: 256

ISBN-13: 9781013281778

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This work presents methods to advance electrophysiological simulations of intracardiac electrograms (IEGM). An experimental setup is introduced, which combines electrical measurements of extracellular potentials with a method for optical acquisition of the transmembrane voltage in-vitro. Thereby, intracardiac electrograms can be recorded under defined conditions. Using experimental and clinical signals, detailed simulations of IEGMs are parametrized, which can support clinical diagnosis. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.

A Multiscale In Silico Study to Characterize the Atrial Electrical Activity of Patients With Atrial Fibrillation : A Translational Study to Guide Ablation Therapy
A Multiscale In Silico Study to Characterize the Atrial Electrical Activity of Patients With Atrial Fibrillation : A Translational Study to Guide Ablation Therapy

Author: Sánchez Arciniegas, Jorge Patricio

Publisher: KIT Scientific Publishing

Published: 2022-05-30

Total Pages: 162

ISBN-13: 3731511703

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The atrial substrate undergoes electrical and structural remodeling during atrial fibrillation. Detailed multiscale models were used to study the effect of structural remodeling induced at the cellular and tissue levels. Simulated electrograms were used to train a machine-learning algorithm to characterize the substrate. Also, wave propagation direction was tracked from unannotated electrograms. In conclusion, in silico experiments provide insight into electrograms' information of the substrate.

ECG Imaging of Ventricular Activity in Clinical Applications
ECG Imaging of Ventricular Activity in Clinical Applications

Author: Schulze, Walther H. W.

Publisher: KIT Scientific Publishing

Published: 2015-08-12

Total Pages: 238

ISBN-13: 3731503743

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ECG imaging was performed in humans to reconstruct ventricular activation patterns and localize their excitation origins. The precision of the non-invasive reconstructions was evaluated against invasive measurements and found to be in line with the state-of-the-art literature. Statistics were produced for various excitation origins and reveal the beat-to-beat robustness of the imaging method.

Multiscale Cohort Modeling of Atrial Electrophysiology : Risk Stratification for Atrial Fibrillation through Machine Learning on Electrocardiograms
Multiscale Cohort Modeling of Atrial Electrophysiology : Risk Stratification for Atrial Fibrillation through Machine Learning on Electrocardiograms

Author: Nagel, Claudia

Publisher: KIT Scientific Publishing

Published: 2023-04-24

Total Pages: 280

ISBN-13: 3731512815

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An early detection and diagnosis of atrial fibrillation sets the course for timely intervention to prevent potentially occurring comorbidities. Electrocardiogram data resulting from electrophysiological cohort modeling and simulation can be a valuable data resource for improving automated atrial fibrillation risk stratification with machine learning techniques and thus, reduces the risk of stroke in affected patients.

Modeling Human Atrial Patho-Electrophysiology from Ion Channels to ECG - Substrates, Pharmacology, Vulnerability, and P-Waves
Modeling Human Atrial Patho-Electrophysiology from Ion Channels to ECG - Substrates, Pharmacology, Vulnerability, and P-Waves

Author: Loewe, Axel

Publisher: KIT Scientific Publishing

Published: 2016-08-03

Total Pages: 342

ISBN-13: 3731505282

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Half of the patients suffering from atrial fibrillation (AF) cannot be treated adequately, today. This book presents multi-scale computational methods to advance our understanding of patho-mechanisms, to improve the diagnosis of patients harboring an arrhythmogenic substrate, and to tailor therapy. The modeling pipeline ranges from ion channels on the subcellular level up to the ECG on the body surface. The tailored therapeutic approaches carry the potential to reduce the burden of AF.

Electrophysiologic Testing
Electrophysiologic Testing

Author: Richard N. Fogoros

Publisher: John Wiley & Sons

Published: 2008-04-15

Total Pages: 307

ISBN-13: 0470750243

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Following the huge success of previous editions,Electrophysiological Testing 4th edition is the must haveresource for students, residents, cardiology fellows, primary carephysicians, cardiologists, nurses, and technicians becauseit: clarifies the role of electrophysiology in the evaluation ofcardiac arrhythmias discusses advances in therapeutic electrophysiology keeping youcompletely up to date provides clear summaries of complex topics is written in a user-friendly and understandable writing styleto make the information easy to digest and recall includes an entirely new chapter on the key field of CardiacResynchronisation Reviews of previous edition: “Many times I have found that EP literature is verytied to research results and bogs down the primary topic and makesit difficult to understand. This book explains EP in plain English!I think it is in a class by itself." EP Technician, GalichiaHeart Hospital, Wichita, KS, USA "It gives a good understanding of EP without getting tootechnical and complex in the explanations. It accomplishes a majortask of “demystifying” the field of EP. It not onlyaddresses the needs of non technical EP Personnel, but alsoprovides a precise overview of EP for general review.”Cardiac NP, St. Jude's Medical Center

Interpreting Cardiac Electrograms
Interpreting Cardiac Electrograms

Author: Kevin Michael

Publisher: BoD – Books on Demand

Published: 2017-10-18

Total Pages: 196

ISBN-13: 9535135716

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This is a reference book aimed at cardiologists, electrophysiologists and fellows in training. It presents an expansive review of cardiac electrogram interpretation in a collation of manuscripts that represent clinical studies, relevant anecdotal cases and basic science chapters evaluating cardiac signal processing pertaining to persistent atrial fibrillation. A diagnostic approach to arrhythmias using a standard ECG, the signal average ECG and fetal ECG is highlighted. Intracardiac ICD electrograms are also explored in terms of trouble shooting and device programming.