Modern Synthesis Processes and Reactivity of Fluorinated Compounds
Modern Synthesis Processes and Reactivity of Fluorinated Compounds

Author: Henri Groult

Publisher: Elsevier

Published: 2016-11-04

Total Pages: 792

ISBN-13: 0128037903

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Modern Synthesis Processes and Reactivity of Fluorinated Compounds focuses on the exceptional character of fluorine and fluorinated compounds. This comprehensive work explores examples taken from all classes of fluorine chemistry and illustrates the extreme reactivity of fluorinating media and the peculiar synthesis routes to fluorinated materials. The book provides advanced and updated information on the latest synthesis routes to fluorocompounds and the involved reaction mechanisms. Special attention is given to the unique reactivity of fluorine and fluorinated media, along with the correlation of those properties to valuable applications of fluorinated compounds. - Contains quality content edited, and contributed, by leading scholars in the field - Presents applied guidance on the preparation of original fluorinated compounds, potentially transferable from the lab scale to industrial applications - Provides practical synthesis information for a wide audience interested in fluorine compounds in many branches of chemistry, materials science, and physics

Aromatic Fluorination
Aromatic Fluorination

Author: James H. Clark

Publisher: CRC Press

Published: 2018-01-10

Total Pages: 199

ISBN-13: 135107833X

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Describes methods for introducing fluorine and small fluorine-containing substituents into aromatic rings Considers traditional and modern synthetic methods, including industrial processes Focuses on the synthesis of selectively fluorinated aromatic molecules that represent an increasingly important class of intermediates Examines both historical development and future trends in this increasingly important area of chemistry

The Curious World of Fluorinated Molecules
The Curious World of Fluorinated Molecules

Author: Konrad Seppelt

Publisher: Elsevier

Published: 2020-10-30

Total Pages: 456

ISBN-13: 0128198753

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The Curious World of Fluorinated Molecules: Molecules Containing Fluorine is the sixth volume in the Progress in Fluorine Science series and is edited by the world-renowned scientist Konrad Seppelt. Dr. Seppelt brings together a team of global experts to uncover the multifaceted nature of the most electronegative element in the Periodic Table. The book explores the fascinating world of unpredictable, fluorine-containing molecules through their discoveries, path to recognition, current state of the art, and impact on the broader fields of fluorinated materials development. This volume will inspire and energize researchers, future scientists, and educators working in fluorine chemistry. - Highlights the current state of fundamental research of fluorinated molecules that either helped to rewrite the fundamental rules of chemistry or impacted modern material technologies - Features contributions from a global team of leading experts in the field - Provides a unique combination of the historical and current examples that explain the unique role that fluorine can play in advancing our understanding of the scientific method at large

Late-Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates
Late-Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates

Author: Al Postigo

Publisher: Elsevier

Published: 2018-09-10

Total Pages: 0

ISBN-13: 9780128129586

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Late-Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates reviews how the use of these techniques on compounds with already known and relevant biological activity can provide new pharmaceutical leads with improved medicinal properties. The fluorination strategies discussed take into account both conventional and novel reagents, including nucleophilic, electrophilic, those of a radical nature, and diverse families of organic compounds, such as (hetero) aromatic rings and aliphatic substrates. Drawing on the authors' expert knowledge, this book provides researchers with a broad set of applicable methods to use in their work.

Organofluorine Chemistry
Organofluorine Chemistry

Author: Kalman J. Szabo

Publisher: John Wiley & Sons

Published: 2021-03-22

Total Pages: 464

ISBN-13: 3527347119

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By presenting novel methods for the efficient preparation of fluorinated compounds and their application in pharmaceutical and agrochemical chemistry as well as medicine, this is a valuable source of information for all researchers in academia and industry!

Late-Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates
Late-Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates

Author: Al Postigo

Publisher: Elsevier

Published: 2018-09-05

Total Pages: 392

ISBN-13: 0128130393

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Late-Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates reviews how the use of these techniques on compounds with already known and relevant biological activity can provide new pharmaceutical leads with improved medicinal properties. The fluorination strategies discussed take into account both conventional and novel reagents, including nucleophilic, electrophilic, those of a radical nature, and diverse families of organic compounds, such as (hetero) aromatic rings and aliphatic substrates. Drawing on the authors' expert knowledge, this book provides researchers with a broad set of applicable methods to use in their work. - Highlights the latest developments in the field in a concise volume - Provides details of key fluorinating reagents across diverse families of organic compounds - Explores the current applications and future potential of fluorine in drug development

Organofluorine Compounds
Organofluorine Compounds

Author: Tamejiro Hiyama

Publisher: Springer Science & Business Media

Published: 2013-03-09

Total Pages: 281

ISBN-13: 3662041642

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In view of increasing interest in organofluorine compounds, this book was undertaken to describe biological and physical properties of organofluorine compounds, synthetic methods of these, their roles in pharmaceutical, agrochemical and material sciences. In particular, the book will emphasize on the usefulness of fluorination reaction, availability of fluorination agents, so that even graduate students who are unfamiliar to this field can understand and participate in this fascinating heteroatom chemistry.

Organic and Inorganic Fluorine Chemistry
Organic and Inorganic Fluorine Chemistry

Author: Axel Haupt

Publisher: Walter de Gruyter GmbH & Co KG

Published: 2021-03-22

Total Pages: 846

ISBN-13: 3110659506

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Organic and Inorganic Fluorine Chemistry provides an introduction to fluorine chemistry and an overview of the most important fluorinated compounds and general preparation techniques. The book is divided into three parts, covering general aspects, inorganic fluorides and fluoroorganic compounds. The inorganic part presents the most important element fluorides and oxyfluorides, their preparation as well as their most characteristic properties. The organic section focuses on the different types of fluorination and the corresponding reagents. The application of these techniques is discussed for many different types of substrates. The book addresses advanced students in chemistry as well as researchers in academia and industry. The readers will benefit from a large number of original references which give access to further information. In addition, study questions at the end of each chapter will help to repeat and internalise the most important aspects.

Fluorination
Fluorination

Author: Jinbo Hu

Publisher: Springer

Published: 2020-08-12

Total Pages: 0

ISBN-13: 9789811038952

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This volume reviews the recent advances in formation of C-F bonds and X-F bonds (X = heteroatom) to produce useful fluorinated molecules for pharmaceuticals, materials and more. Reactions and methods associated with fluorination, including monofluorination, difluorination, trifluorination and other polyfluorination that have emerged within the past few years are systematically discussed. With contributions from front-line researchers in this field from both academia and industry, this book provides a valuable resource for scholars, graduate students as well as professionals.