Clinical Pharmacology During Pregnancy is written for clinicians, physicians, midwives, nurses, pharmacists and other medical professionals directly involved in the care of women during pregnancy. This book focuses on the impact of pregnancy on drug disposition and also includes coverage of treatments for diseases of specific body systems, as well as essential content on dosing and efficacy. Written in a clear and practical manner, this reference provides easily accessible information and clinical guidance on how best to treat women with medications during pregnancy.
An A-Z listing of drugs by generic name. Each monograph summarizes the known and/or possible effects of the drug on the fetus. It also summarizes the known/possible passage of the drug into the human breast milk. A careful and exhaustive summarization of the world literature as it relates to drugs in pregnancy and lacation. Each monograph contains six parts: generic US name, Pharmacologic class, Risk factor, Fetal risk summary, Breast feeding summary, References
The landmark text that has served generations of obstetrician-gynecologists—fully updated with the most current perspectives of the field A Doody's Core Title for 2023! Williams Obstetrics has defined the discipline for generations of obstetrician-gynecologists. Written by authors from the nationally renowned University of Texas Southwestern Medical Center and Parkland Hospital, the new edition of this authoritative, evidence-based work maintains its trademark comprehensive coverage and applicability at the bedside, while offering the most current information and insights. The culmination of a century of clinical thought, Williams Obstetrics, 26th Edition delivers expert coverage of obstetrical complications, such as preterm labor, pregnancy-related hypertension, infection, and hemorrhage. It additionally offers foundational content on reproductive anatomy, physiology, and prenatal care. The authors have enhanced this edition with 1,000+ full-color illustrations, plus an increased emphasis on the fast-growing subspecialty of Maternal-Fetal Medicine. No other text matches the long-established scientific rigor and accessibility of Williams Obstetrics. With its state-of-the-art design and review of the newest advances and protocols, this not-be-missed clinical companion brings positive outcomes within reach. New and updated content includes: Increased focus on Maternal-Fetal Medicine Greater coverage of hypertension and hemorrhage Deeper insights into in-utero complications Expanded fetal t section includes cutting-edge fetal imaging, genetics, prenatal diagnosis, and fetal disorders and therapy Basic science, physiology of labor, preterm labor updated with contemporaneous publications in the literature More obstetrical sonography figures Eye-catching illustrations, including updated graphs, sonograms, MRIs, photographs, and photomicrographs
Abstract: This book addresses the use of drug groups for various clinical indications during pregnancy. In general, non-pharmacologic remedies are recommended if these will suffice before drug therapy is instituted. Known adverse effects of drugs are documented and caution is advised because of the many unknowns about long-term effects of drug exposure to the developing fetus. Drugs used for the common cold, antituberculosis agents, antihypertensives, anticonvulsants, and marijuana and cocaine are included.
This authoritative international text on fetal therapy is the first to cover all three classes of fetal therapy in one book: transplacental drug treatment, invasive procedures, and fetal surgery. It emphasises treatments which have become established in clinical practice in this rapidly developing field, as well as reviewing those that have failed to live up to initial expectation, and discusses the likely impact of new therapies on the horizon. The editors head a team of American, European and Australasian authors, all of whom are leading experts in their respective fields. The text is authoritative, evidence based, and balanced, finding the common ground between the opposing camps of 'enthusiasts' and 'therapeutic nihilists'. It will be an essential source of reference for all those involved in the care of the unborn child, and particularly for obstetricians training in fetal medicine.
The study of birth defects has assumed an importance even greater now than in the past because mortality rates attributed to congenital anomalies have declined far less than those for other causes of death, such as infectious and nutritional diseases. It is estimated that as many as 50% of all pregnancies terminate as miscarriages. In the majority of cases this is the result of faulty development. Major congenital malformations are found in at least 2% of all liveborn infants, and 22% of all stillbirths and infant deaths are associated with severe congenital anomalies. Teratological studies of an experimental nature are neither ethical nor justifiable in humans. Numerous investigations have been carried out in laboratory animals and other experimental models in order to improve our understanding of abnormal intra-uterine development. In less than two decades the field of experimental teratology has advanced phenomenally. As a result of the wide range of information that is now accumulating, it has become possible to obtain an insight into the causes, mechanisms and prevention of birth defects. However, considerable work will be needed before these problems can be resolved. This book brings together some of the more recent and important research findings related to the mechanisms and pathogenesis of abnormal develop ment. It is not only a documentation of the latest experimental work, but it also points out future directions that seem productive and challenging.
"This book is a rare find for APRNs, especially PNPs and NNPs, and provides excellent APRN collaboration instances in everyday clinical and academic settings. The chapters are written by interprofessional healthcare providers, such as NNPs and PharmDs, and provide information and practice guidelines from a collaborative perspective. " –Holly Wei, PhD, RN, CPN, NEA-BC, FAAN Professor and Assistant Dean for PhD Program University of Louisville School of Nursing This is the first text to address fetal and neonatal pharmacology for the APN and nursing student. With a strong focus on interprofessional collaboration, it delivers core pharmacologic concepts and practice guidelines in a clear, systematic manner for ease of use. This resource reflects real-word scenarios as it discusses perinatal and intrapartum pharmacologic therapies and their implications for fetuses and neonates. It covers such postnatal pharmacology considerations as human milk and maternal drug addiction. A table including 100 of the most commonly used medications prescribed in the NICU serves as a quick reference for both academic and clinical settings. The text explores the genesis, evolution, and current knowledge surrounding pharmacologic therapies used to treat common problems afflicting preterm and critically ill neonates. Chapters, written by interprofessional teams, include illustrations and concept maps of key content—promoting active learning for visual and tactile learners, learning objectives, and discussion questions. The text meets the accreditation requirements for MSN and DNP programs offering the 3P courses to neonatal and pediatric NP students, Clinical Nurse Specialist students, and midwifery students. Key Features: Provides clear, concise descriptions of principles of fetal and neonatal pharmacology Includes illustrations and concept maps providing visual and tactile learners with tools to engage and demonstrate active learning Presents illustrations and "concept maps" of key content to foster active learning for visual and tactile learners Offers Learning Objectives and Discussion Questions in each chapter Includes a table of 100 commonly used NICU medications Provides core curricular content, written by interprofessional author teams, which aligns with the 2021 AACN Essentials and 2022 NTFS Standards for Quality Nurse Practitioner Education
