Fast Facts: Leucemia

Fast Facts: Leucemia

Author: J. Loke

Publisher: Karger Medical and Scientific Publishers

Published: 2019-11-28

Total Pages: 140

ISBN-13: 3318066338

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Aunque la incidencia y prevalencia de leucemia está aumentando a nivel mundial, los avances en el diagnóstico y el tratamiento indican que las tasas de supervivencia también están aumentando. Comenzando con una descripción detallada de la hematopoyesis y lo que está mal en caso de la leucemia, esta guía concisa abarca todos los aspectos de los cuatro subtipos más frecuentes de la enfermedad: leucemia mieloide aguda (AML), leucemia linfoblástica aguda (ALL), leucemia mieloide crónica (CML) y leucemia linfocítica crónica (CLL). Este libro considera las causas y factores de riesgo para cada subtipo de leucemia, las pruebas diagnósticas iniciales y confirmatorias (incluyendo métodos de citogenética y genética molecular) y las opciones de tratamiento más recientes. Tanto los efectos de la enfermedad como los efectos adversos del tratamiento siguen representando un desafío complejo y se considera el abordaje multidisciplinario necesario para una atención de apoyo efectiva. Por último, se examinan las complicaciones urgentes que requieren atención de emergencia. Diseñado como una guía integral para enfermeras especializadas, médicos de atención primaria y residentes de hematología/oncología, este recurso ayudará a quienes no son especialistas a identificar la leucemia en etapas tempranas y proporciona una comprensión detallada de la patología y la base genética de la enfermedad, las opciones de tratamiento y los abordajes efectivos a la atención de urgencia y cuidados de apoyo.


Fast Facts: Leukemia

Fast Facts: Leukemia

Author: J. Loke

Publisher: Karger Medical and Scientific Publishers

Published: 2022-03-02

Total Pages: 138

ISBN-13: 3318069493

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Leukemia is a hematologic malignancy arising from hematopoietic stem cells (HSCs) in the bone marrow. Starting with a detailed description of hematopoiesis and what goes wrong in leukemia, this concise guide covers all aspects of the four most common subtypes of the disease. Although the incidence and prevalence of leukemia are rising worldwide, survival rates are also increasing. However, both the effects of the disease and the adverse effects of treatment remain complex challenges. Yet, as our understanding of the molecular landscape increases, therapeutic options are becoming more personalized. This revised and updated second edition of 'Fast Facts: Leukemia' addresses the causes and risk factors for each subtype of leukemia, the initial and confirmatory diagnostic tests, and the latest treatment options. Designed as a comprehensive primer for physician assistants, nurse practitioners, primary care providers, oncology nurses, hematology/ oncology trainees and pharmacists, this resource will help the non-specialist and those in training to identify leukemia early and provide a thorough understanding of the pathology and genetic basis of the disease, treatment options, and effective approaches to emergency and supportive care. Table of Contents: • Understanding blood and its components • What is leukemia? • Epidemiology, etiology and risk factors • Diagnosis • Staging and general management • Supportive care • Emergencies in leukemia


Fast Facts: Leukemia

Fast Facts: Leukemia

Author: Justin Loke

Publisher: Karger Medical and Scientific Publishers

Published: 2022-02-22

Total Pages: 138

ISBN-13: 3318069965

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Leukemia is a hematologic malignancy arising from hematopoietic stem cells (HSCs) in the bone marrow. Starting with a detailed description of hematopoiesis and what goes wrong in leukemia, this concise guide covers all aspects of the four most common subtypes of the disease. Although the incidence and prevalence of leukemia are rising worldwide, survival rates are also increasing. However, both the effects of the disease and the adverse effects of treatment remain complex challenges. Yet, as our understanding of the molecular landscape increases, therapeutic options are becoming more personalized. This revised and updated second edition of 'Fast Facts: Leukemia' addresses the causes and risk factors for each subtype of leukemia, the initial and confirmatory diagnostic tests, and the latest treatment options. Designed as a comprehensive primer for physician assistants, nurse practitioners, primary care providers, oncology nurses, hematology/ oncology trainees and pharmacists, this resource will help the non-specialist and those in training to identify leukemia early and provide a thorough understanding of the pathology and genetic basis of the disease, treatment options, and effective approaches to emergency and supportive care. Table of Contents: • Understanding blood and its components • What is leukemia? • Epidemiology, etiology and risk factors • Diagnosis • Staging and general management • Supportive care • Emergencies in leukemia


Fast Facts: Acute Lymphoblastic Leukemia

Fast Facts: Acute Lymphoblastic Leukemia

Author: Bela Wrench

Publisher: Karger Medical and Scientific Publishers

Published: 2022-06-30

Total Pages: 108

ISBN-13: 3318069779

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Acute lymphoblastic leukemia (ALL) is the most diagnosed childhood cancer worldwide. Although rare in adults, this aggressive cancer also shows a second smaller incidence peak in later middle age.

Modern genetic profiling techniques are providing a better understanding of the molecular biology of ALL, which, in turn, is leading to significant advances in diagnosis, prognostication and therapy selection. Ongoing refinement of risk-adapted frontline treatment protocols, use of novel targeted therapies and better supportive care are improving outcomes for patients with ALL.

Fast Facts: Acute Lymphoblastic Leukemia covers the epidemiology, etiology, diagnosis and classification of ALL as well as the measurement of minimal residual disease to determine prognosis. It provides guidance on frontline therapies and the treatment of relapsed and refractory ALL, including the use of newer targeted agents and the role of allogeneic stem-cell transplantation. Looking to the future, it also considers the approaches and refinements that are in development for ALL. Table of Contents:

  • Epidemiology, pathophysiology and etiology
  • Diagnosis
  • Prognostic factors
  • Treatment
  • Relapsed or refractory ALL
  • Future directions

  • All-in-One Nursing Care Planning Resource - E-Book

    All-in-One Nursing Care Planning Resource - E-Book

    Author: Julie S. Snyder

    Publisher: Elsevier Health Sciences

    Published: 2023-08-05

    Total Pages: 840

    ISBN-13: 0323825370

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    - NEW and UNIQUE! Care plan components are now labeled as appropriate with the six cognitive skills identified in the National Council of State Boards of Nursing (NCSBN) Clinical Judgment Measurement Model (CJMM) to help students identify, develop, and implement the clinical judgment skills needed for success on the Next-Generation NCLEX® Exam (NGN) and in clinical practice. - NEW! Additional care plans on Infection, Delirium, and Breastfeeding. - UPDATED! Content throughout reflects the latest evidence-based treatment guidelines and national and international treatment protocols.


    Canine and Feline Infectious Diseases

    Canine and Feline Infectious Diseases

    Author: Jane E. Sykes

    Publisher: Elsevier Health Sciences

    Published: 2013-08-09

    Total Pages: 933

    ISBN-13: 0323241948

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    Canine and Feline Infectious Diseases is a practical, up-to-date resource covering the most important and cutting-edge advances in the field. Presented by a seasoned educator in a concise, highly visual format, this innovative guide keeps you current with the latest advances in this ever-changing field. 80 case studies illustrate the clinical relevance of the major infectious disease chapters. - Well-organized Major Infectious Diseases chapters break down content by etiologic agent and epidemiology, clinical signs and their pathophysiology, physical examination findings, diagnosis, treatment and prognosis, immunity, prevention, and public health implications. - Over 80 case studies illustrate how the information provided can be applied in everyday practice. - Logical approach to laboratory diagnosis guides you through all the steps needed to accurately diagnose and treat viral, bacterial, fungal, protozoal, and algal diseases. - Practical protocols provided by expert clinicians guide you in the management of canine and feline patients suspected to have infectious diseases, including handling, disinfection, isolation, and vaccination protocols. - Over 500 full color images – geographic distribution maps, life cycle drawings, and hundreds of color photographs – visually illustrate and clarify complex issues. - Easy-to-understand tables and boxes make content quickly accessible, eliminating the need to sort through dense text for critical information in the clinical setting.


    Orbital Imaging E-Book

    Orbital Imaging E-Book

    Author: F. Allan Midyett

    Publisher: Elsevier Health Sciences

    Published: 2014-11-18

    Total Pages: 275

    ISBN-13: 0323354270

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    Orbital Imaging, by Dr. F. Allan Midyett and Dr. Suresh K. Mukherji, covers the majority of orbital pathologic entities you’re likely to encounter in daily practice or during board examination. Radiologists and ophthalmologists alike will benefit from the concise focus on pertinent imaging modalities emphasizing CT and MR of the globe and orbit, presented with bulleted lists and fast facts for quick clinical correlation. This unique, compact reference is the one you’ll consistently reach for, whether you’re learning orbital imaging for the first time, in need of a quick review, studying for exams, or looking up cases in the reading room. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Easy to digest format promotes quick navigation to zero in on what is important: - Key Chapter Points give a "bird’s eye view" of a particular pathologic process - Classic Clues sum up pathologic processes and indicate when you can expect to see those findings - Content snapshots get to the point, including fast facts, epidemiology and pathology, data overviews on treatment and prognosis, and quick tips on the most frequently seen CT and MRI features. Differential Diagnosis sections tell you exactly which features to critically compare, that at first glance may look identical. Superb illustrations depict important and fascinating diagnostic dilemmas.


    Allogeneic Stem Cell Transplantation

    Allogeneic Stem Cell Transplantation

    Author: Hillard M. Lazarus

    Publisher: Springer Science & Business Media

    Published: 2010-03-02

    Total Pages: 885

    ISBN-13: 1597454788

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    Since the original publication of Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Allogeneic hematopoietic stem cell transplantation (HSC) has undergone several fast-paced changes. In this second edition, the editors have focused on topics relevant to evolving knowledge in the field in order to better guide clinicians in decision-making and management of their patients, as well as help lead laboratory investigators in new directions emanating from clinical observations. Some of the most respected clinicians and scientists in this discipline have responded to the recent advances in the field by providing state-of-the-art discussions addressing these topics in the second edition. The text covers the scope of human genomic variation, the methods of HLA typing and interpretation of high-resolution HLA results. Comprehensive and up-to-date, Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Second Edition offers concise advice on today's best clinical practice and will be of significant benefit to all clinicians and researchers in allogeneic HSC transplantation.


    Health Risks of Radon and Other Internally Deposited Alpha-Emitters

    Health Risks of Radon and Other Internally Deposited Alpha-Emitters

    Author: National Research Council

    Publisher: National Academies Press

    Published: 1988-02-01

    Total Pages: 623

    ISBN-13: 0309037891

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    This book describes hazards from radon progeny and other alpha-emitters that humans may inhale or ingest from their environment. In their analysis, the authors summarize in one document clinical and epidemiological evidence, the results of animal studies, research on alpha-particle damage at the cellular level, metabolic pathways for internal alpha-emitters, dosimetry and microdosimetry of radionuclides deposited in specific tissues, and the chemical toxicity of some low-specific-activity alpha-emitters. Techniques for estimating the risks to humans posed by radon and other internally deposited alpha-emitters are offered, along with a discussion of formulas, models, methods, and the level of uncertainty inherent in the risk estimates.