Exploring New Findings on Amyloidosis
Exploring New Findings on Amyloidosis

Author: Ana Maria Fernandez-Escamilla

Publisher: BoD – Books on Demand

Published: 2016-08-24

Total Pages: 348

ISBN-13: 9535126180

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Amyloid protein aggregates are involved in ''protein-misfolding diseases'' of enormous social and economic impact, still with no effective therapies. The most prevalent amyloid pathologies are related to neurodegenerative diseases, but amyloidosis also affects other organs. The majority of the studies includes serious health connotations on amyloids. However, not all amyloid fibers play a detrimental role in host. An increasing number of studies shows an important beneficial role as ''functional amyloids''. This book opens an exciting door to provide up-to-date information about the function and the mechanisms of the amyloid formation process from the structural, biophysical, biomedical, and nanotechnological perspective, combining the new findings on toxic and functional amyloids studies using theoretical and experimental approaches to fight against amyloid-based diseases.

Amyloidosis
Amyloidosis

Author: Morie A. Gertz

Publisher: Springer Science & Business Media

Published: 2010-06-14

Total Pages: 243

ISBN-13: 1607616319

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An up-to-date reference on this fascinating set of complex disorders, this book features the most comprehensive strategies for diagnosing, classifying, imaging, treating, and managing amyloidosis in multiple organ systems. Beneficial to the spectrum of practitioners from residents to sub-specialists, this book is a succinct authoritative text written by leaders in the field. The authors provide instruction on all forms of amyloidosis - including primary amyloidosis (AL), secondary amyloidosis (AA), and familial amyloidosis. With essential treatment algorithms, Amyloidosis: Diagnosis and Treatment is the gold-standard for all hematologists, oncologists, and internists caring for patients with this complex disease.

Amyloidosis
Amyloidosis

Author: Raquel Watts

Publisher: Nova Biomedical Books

Published: 2016-12

Total Pages: 0

ISBN-13: 9781634858847

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Amyloidosis is a result of the abnormal deposition of amyloid resulting in the disruption of organ and tissue function, which can be localised or systemic, with the kidney being most frequently affected. This book discusses the risk factors, treatment options and clinical aspects of amyloidosis. Chapter One explores amyloid cardiomyopathy. Chapter Two summarises current investigations utilising RNAi and immunotherapy to target the amyloid protein itself. Chapter Three reviews genetic counseling as an important component of the treatment algorithm for amyloidosis. Chapter Four discusses tissue examination in a diagnostic procedure. Chapter Five reviews protein studies in light-chain amyloidosis.

Amyloid and Related Disorders
Amyloid and Related Disorders

Author: Maria M. Picken

Publisher: Humana Press

Published: 2015-08-17

Total Pages: 536

ISBN-13: 3319192949

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The second edition of this text presents an overview of the most recent developments in this area including clinical presentation, etiology, pathogenesis, and differential diagnosis. The rationale for various therapies, including transplantation, is discussed and tissue diagnosis (its pitfalls and strategies for avoiding them) and laboratory support are included. The involvement of all major organ systems including renal/genitourinary, cardiac, gastrointestinal, pulmonary, peripheral nerve/central nervous system, soft tissue, skin, lymph node/spleen and bone marrow pathology is also covered. Amyloid and Related Disorders, Second Edition will be invaluable to specialized and general pathologists as well as cytopathologists. Other medical professionals may also benefit from this concise update on the systemic amyloidoses.

Periodontitis and Systemic Diseases
Periodontitis and Systemic Diseases

Author: Josefine Hirschfeld

Publisher: Quintessenz Verlag

Published: 2021-04-19

Total Pages: 502

ISBN-13: 3868675574

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The association between periodontitis and systemic diseases has become a hot topic in recent years. This comprehensive book reviews the clinical evidence and biological plausibility of the many systemic diseases that have been linked to periodontitis. Edited by Dr Josefine Hirschfeld and Prof Iain L.C. Chapple, experts in each field discuss the mechanisms at work, citing the available key literature and clearly summarising current knowledge and understanding of the associations between periodontitis and diabetes mellitus, cardiovascular diseases, chronic kidney disease, inflammatory bowel diseases, rheumatoid arthritis, respiratory diseases, pregnancy and fertility, malignancy, neurodegenerative diseases, stress and depression, and autoimmunity. Each chapter critically appraises the existing evidence, providing comprehensive, contemporary and well-considered insights into the clinical evidence and biological plausibility of each condition, as well as the limitations of existing studies and how these can be overcome in the future. Periodontitis and Systemic Diseases: Clinical Evidence and Biological Plausibility is an indispensable reference for both clinicians and researchers.

Mitochondria in Health and Disease
Mitochondria in Health and Disease

Author: Ray Griffiths

Publisher: Singing Dragon

Published: 2018-04-19

Total Pages: 338

ISBN-13: 0857012886

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What are the functions of mitochondria in the human body? Why might they stop working properly and what can happen as a result? How can personalized nutrition help to optimize mitochondrial function and prevent or address chronic conditions? This innovative book explores the incredibly complex biochemical roles of mitochondria in health and disease. When healthy, mitochondria provide us with ninety percent of our body's energy. When unhealthy, this can lead to many chronic and degenerative conditions including cancer and Alzheimer's disease. This guide helps practitioners to identify the mitochondrial dysfunction underlying a wide range of health complaints, and provides inspiration about relevant and emerging mitochondria-supportive dietary regimes and nutrients to explore within the model of personalized nutrition.

Encyclopedia of Amyloidosis
Encyclopedia of Amyloidosis

Author: Cassandra Jones

Publisher:

Published: 2015-02-10

Total Pages: 0

ISBN-13: 9781632421272

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This book combines a basic understanding of amyloidosis with a discussion of the advancements in treatment strategies of this disease. Amyloidosis is a gradually progressive condition characterized by the occurrence of extracellular fibrillar proteins in many organs and tissues. It has systemic and locally confined forms, and both these forms have been a point of interest for many experts. There have been a large number of case studies regarding amyloidosis in the last few years. This book intends to help students and even experts in comprehending the topic thoroughly and accomplish their respective researches.

Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies
Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies

Author: Ramasamy Paulmurugan

Publisher: Academic Press

Published: 2021-06-25

Total Pages: 832

ISBN-13: 0128215682

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Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies brings current knowledge from an international team of experts on the science and clinical management of glioblastoma chemoresistance. The book discusses topics such as molecular mechanisms of chemoresistance, experimental models to study chemoresistance, chemoresistance to drugs other than Temozolomide, and specific strategies to reverse chemoresistance. Additionally, it encompasses information on how to mitigate chemoresistance by targeted enhancement of p53 function. This book is a valuable resource for cancer researchers, oncologists, neuro-oncologists and other members of the biomedical field. Glioblastoma (GBM) is the most invasive and malignant primary brain tumor in humans with poor survival after diagnosis, therefore it is imperative that molecular and cellular mechanisms behind therapy resistant GBM cells, as well as the therapeutic strategies available to counter the resistance are comprehensively understood. - Provides comprehensive, core knowledge related to the entire discipline of glioblastoma chemoresistance, from its many etiological mechanisms, to specific strategies to reverse resistance - Presents current information from an international team of experts on the basic science, pre-clinical research, and clinical management of glioblastoma chemoresistance - Discusses molecular and cellular mechanisms behind therapy resistant glioblastoma cells, as well as the therapeutic strategies available to counter this resistance

Specialty Imaging: HRCT of the Lung E-Book
Specialty Imaging: HRCT of the Lung E-Book

Author: Santiago Martínez-Jiménez

Publisher: Elsevier Health Sciences

Published: 2017-07-22

Total Pages: 542

ISBN-13: 0323524958

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Part of the highly regarded Specialty Imaging series, this fully updated second edition by Drs. Santiago Martínez-Jiménez, Melissa L. Rosado-de-Christenson, and Brett W. Carter, reflects the many recent changes in HRCT diagnostic interpretation. An easy-to-read bulleted format and state of the art imaging examples guide you step-by-step through every aspect of thin-section CT and HRCT in the evaluation of patients with suspected lung disease. This book is an ideal resource for radiologists who need an easily accessible tool to help them understand the indications, strengths, and limitations of HRCT in their practice. - Superb illustrations with comprehensive captions display both typical and variant findings on HRCT scans - Introductory sections are specifically designed to lead the general radiologist to differential diagnoses from specific imaging findings, pathologic patterns, or from the disease/pathology itself - Time-saving bulleted format distills essential information for fast and easy comprehension - Updated content includes changes in HRCT interpretation and novel disease processes such as DIPNECH, new classification of idiopathic interstitial pneumonias, airway-centered interstitial fibrosis, light-chain deposition disease, and interstitial pneumonia with autoimmune features (IPAF) - Fully revised throughout with new references, images, and histopathologic correlations