This book is aimed at scientists, technologists, engineers, and undergraduate and graduate students involved in analytical and process biochemistry and biotechnology. It reviews the potentialities of light-emitting reaction associated with the sensor approach.The book introduces the concepts of sensors and biosensors and places bio- and chemi-luminescent sensors in the general context of biosensors. It then briefly describes luminescence phenomena and provides some basic knowledge necessary for understanding and exploiting light-emitting reactions. These luminescence reactions, important from an analytical standpoint, are described. Also the applications of bio- and chemi-luminescence which make use of immobilized reagents are explained. Finally, there is discussion of bio- and chemi-luminescent sensors, most of them including fiber optics.
In this collection of essays Allan Franklin defends the view that science provides us with knowledge about the world which is based on experimental evidence and on reasoned and critical discussion. In short, he argues that science is a reasonable enterprise. He begins with detailed studies of four episodes from the history of modern physics: (1) the early attempts to detect gravity waves, (2) how the physics community decided that a proposed new elementary particle, 17-keV neutrino, did not exist, (3) a sequence of experiments on K meson decay, and (4) the origins of the Fifth Force hypothesis, a proposed modification of Newton's Law of Universal Gravitation. The case studies are then used to examine issues such as how discord between experimental results is resolved, calibration of an experimental apparatus and its legitimate use in validating an experimental result, and how experimental results provide reasonable grounds for belief in both the truth of physical theories and in the existence of the entities involved in those theories. This book is a challenge to the critics of science, both postmodern and constructivist, to provide convincing alternative explanations of the episodes and issues discussed. It should be of interest to philosophers, historians, and sociologists of science, and to scientists themselves.
Neutrinos play a decisive part in nuclear and elementary particle physics, as well as in astrophysics and cosmology. Some of their most basic properties, such as their mass and charge conjugation symmetry, are largely unknown. This book focuses on what we know and may hope to know about the mass of the neutrino and its particle-antiparticle symmetry. Topics include neutrino mixing, neutrino decay, neutrino oscillations, double beta decay, solar neutrinos, supernova neutrinos and related issues. The authors stress the physical concepts, and discuss both theoretical and experimental techniques. This updated second edition differs from the first in that it contains an expanded coverage of experimental results and theoretical advances. Since publication of the first edition, many issues that were at that time unresolved, such as tritium beta decay and reactor neutrino oscillations, have been clarified and are discussed here. Also included is an expanded coverage of solar and supernova neutrinos. This book deals with one of the most intriguing issues in modern physics, and will be of value to researchers, graduate students and advanced undergraduates specializing in experimental and theoretical particle physics and nuclear physics.
Reviews the current state of knowledge of neutrino masses and the related question of neutrino oscillations. After an overview of the theory of neutrino masses and mixings, detailed accounts are given of the laboratory limits on neutrino masses, astrophysical and cosmological constraints on those masses, experimental results on neutrino oscillations, the theoretical interpretation of those results, and theoretical models of neutrino masses and mixings. The book concludes with an examination of the potential of long-baseline experiments. This is an essential reference text for workers in elementary-particle physics, nuclear physics, and astrophysics.
Nuclear double beta decay is one of the most promising tools for probing beyond-the-standard-model physics on beyond-accelerator energy scales. It is already now probing the TeV scale, on which new physics should manifest itself according to theoretical expectations. Only in the early 1980s was it known that double beta decay yields information on the Majorana mass of the exchanged neutrino. At present, the sharpest bound for the electron neutrino mass arises from this process. It is only in the last 10 years that the much more far-reaching potential of double beta decay has been discovered. Today, the potential of double beta decay includes a broad range of topics that are equally relevant to particle physics and astrophysics, such as masses of heavy neutrinos, of sneutrinos, as SUSY models, compositeness, leptoquarks, left-right symmetric models, and tests of Lorentz symmetry and equivalence principle in the neutrino sector. Double beta decay has become indispensable nowadays for solving the problem of the neutrino mass spectrum and the structure of the neutrino mass matrix — together with present and future solar and atmospheric neutrino oscillation experiments. Some future double beta experiments (like GENIUS) will be capable to be simultaneously neutrino observatories for double beta decay and low-energy solar neutrinos, and observatories for cold dark matter of ultimate sensitivity.This invaluable book outlines the development of double beta research from its beginnings until its most recent achievements, and also presents the outlook for its highly exciting future.
Nuclear double beta decay is one of the most promising tools for probing beyond-the-standard-model physics on beyond-accelerator energy scales. It is already now probing the TeV scale, on which new physics should manifest itself according to theoretical expectations. Only in the early 1980s was it known that double beta decay yields information on the Majorana mass of the exchanged neutrino. At present, the sharpest bound for the electron neutrino mass arises from this process. It is only in the last 10 years that the much more far-reaching potential of double beta decay has been discovered. Today, the potential of double beta decay includes a broad range of topics that are equally relevant to particle physics and astrophysics, such as masses of heavy neutrinos, of sneutrinos, as SUSY models, compositeness, leptoquarks, left-right symmetric models, and tests of Lorentz symmetry and equivalence principle in the neutrino sector. Double beta decay has become indispensable nowadays for solving the problem of the neutrino mass spectrum and the structure of the neutrino mass matrix OCo together with present and future solar and atmospheric neutrino oscillation experiments. Some future double beta experiments (like GENIUS) will be capable to be simultaneously neutrino observatories for double beta decay and low-energy solar neutrinos, and observatories for cold dark matter of ultimate sensitivity. This invaluable book outlines the development of double beta research from its beginnings until its most recent achievements, and also presents the outlook for its highly exciting future. Contents: Double Beta Decay OCo Historical Retrospective and Perspectives; Original Articles: From the Early Days until the Gauge Theory Era; The Nuclear Physics Side OCo Nuclear Matrix Elements; The Nuclear Physics Side OCo Nuclear Matrix Elements; Effective Neutrino Masses from Double Beta Decay, Neutrino Mass Models and Cosmological Parameters OCo Present Status and Prospects; Other Beyond Standard Model Physics: From SUSY and Leptoquarks to Compositeness and Quantum Foam; The Experimental Race: From the Late Eighties to the Future; The Future of Double Beta Decay; Appendices: Ten Years of HeidelbergOCoMoscow Experiment; The Potential Future OCo GENIUS. Readership: Particle physicists, nuclear physicists and astrophysicists."
