This book is the fourth edition of a highly regarded text which was first published in 1988. It introduces the reader to the interpretation of routine laboratory biochemical test results and covers all aspects of interpretative chemical pathology (including reproductive endocrinology, which was not covered previously). The approach is based on case material from the authors' laboratory and employs algorithms and similar aids for interpretation. The material is structured so that it is comprehensible to beginners as well as being useful for the more experienced practitioners. The envisaged audience is medical undergraduates, general practitioners, clinical biochemists and laboratory technicians.
This book has been written primarily for medical students and junior doctors in clinical practice, but would also be a useful reference for postgraduate students in chemical pathology (clinical biochemistry), laboratory scientists, pathologists and medical laboratory technologists. It covers the field of chemical pathology, the biochemical basis of disease, and provides a basic understanding of the relationship between abnormal biochemical test results and disease states. A rational approach to proper selection and interpretation of biochemical investigations is adopted for each organ system or analyte covered in the 28 chapters. Emphasis is placed on areas and problems most commonly met with in clinical practice. Meant primarily as an introductory study book to the subject rather than as a reference text, the materials have been presented in a clear, condensed format to aid the study process. The written text is amply supplemented with relevant illustrations.
Toxicologic pathology integrates toxicology and the disciplines within it (such as biochemistry, pharmacodynamics and risk assessment) to pathology and its related disciplines (such as physiology, microbiology, immunology, and molecular biology). Fundamentals of Toxicologic Pathology Second Edition updates the information presented in the first edition, including five entirely new chapters addressing basic concepts in toxicologic pathology, along with color photomicrographs that show examples of specific toxicant-induced diseases in animals. The current edition also includes comparative information that will prove a valuable resource to practitioners, including diagnostic pathologists and toxicologists. - 25% brand new information, fully revised throughout - New chapters: Veterinary Diagnostic Toxicologic Pathology; Clinical Pathology; Nomenclature: Terminology for Morphologic Alterations; Techniques in Toxicologic Pathology - New color photomicrographs detailing specific toxicant-induced diseases in animals - Mechanistic information integrated from both toxicology and pathology discussing basic mechanisms of toxic injury and morphologic expression at the subcellular, cellular, and tissue levels
This guide provides an easy-to-use desk reference for diagnostic information on commonly used hematology, clinical chemistry and urinalysis parameters. Additional reference materials are provided as an aid in evaluating clinical pathology data. For many toxicologists, the evaluation of hematology, clinical chemistry and urinalysis data can be the most challenging aspect of animal toxicity studies. In a typical toxicity study, dozens of parameters are measured several times over the course of the study. There may be hundreds of data points, each of which needs to be considered. A Toxicologist’s Guide to Clinical Pathology in Animals will serve as an essential primer for toxicologists in training and in industry as well as for researchers and professionals in a veterinary practice or a laboratory.
Provides the information needed to interpret clinical laboratory assays of domestic mammals Fundamentals of Veterinary Clinical Pathology, Third Edition presents thoroughly updated and detailed information to promote appropriate clinical laboratory testing and interpretation of test results for common domestic mammals. Presented in an easy-to-use outline format complemented by many relevant tables and illustrations, the book is now in full color. This evidence-based guide synthesizes the laboratory principles, physiology, assays, analytical concepts, pathophysiologic states, and pathophysiologic processes relevant to detecting, evaluating, and understanding disorders in dogs, cats, horses, cattle, and camelids. Content additions include two entirely new chapters on synovial and cerebrospinal fluid analysis, as well as expanded sections on blood typing and crossmatching, viscoelastic testing, protein electrophoresis, positive acute-phase proteins, mixed acid-base disorders, vitamin D analysis, analytical and biological variation, blood smear evaluation, and more. New clinical tests and methods, useful data patterns, and additional disorders and pathologic processes are integrated throughout. Providing a conceptual understanding applicable to many species and serving as a valuable clinical reference, Fundamentals of Veterinary Clinical Pathology: Uses consistent terminology and chapter organization featuring separate sections for physiologic concepts, analytical methods, and interpretation of results Provides pathophysiologic explanations of laboratory abnormalities Allows easy access to information on disorders and conditions, grouping them by common mechanisms or processes and ordering them in parallel across interpretive tables and text Features a wealth of high-quality illustrations and photomicrographs throughout the text Includes extensive referencing on the companion website to support statements and provide direction for further reading Fundamentals of Veterinary Clinical Pathology, Third Edition is an excellent textbook for veterinary students taking clinical pathology courses, as well as a valuable resource for clinical and anatomic pathology residents, medicine and surgery residents, and practicing veterinarians.
Essential Concepts in Molecular Pathology, Second Edition, offers an introduction to molecular genetics and the "molecular" aspects of human disease. The book illustrates how pathologists harness their understanding of these entities to develop new diagnostics and treatments for various human diseases. This new edition offers pathology, genetics residents, and molecular pathology fellows an advanced understanding of the molecular mechanisms of disease that goes beyond what they learned in medical and graduate school. By bridging molecular concepts of pathogenesis to the clinical expression of disease in cell, tissue and organ, this fully updated, introductory reference provides the background necessary for an understanding of today's advances in pathology and medicine. - Explains the practice of "molecular medicine" and the translational aspects of molecular pathology, including molecular diagnostics, molecular assessment and personalized medicine - Orients non-pathologists on what pathologists look for and how they interpret their observational findings based on histopathology - Provides the reader with what is missing from most targeted introductions to pathology—the cell biology behind pathophysiology
Get the foundational knowledge you need to successfully work in a real-world, clinical lab with Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, 8th Edition. From highly respected clinical chemistry expert Nader Rifai, this condensed, easier-to-understand version of the acclaimed Tietz Textbook of Clinical Chemistry and Molecular Diagnostics uses a laboratory perspective to guide you through selecting and performing diagnostic lab tests and accurately evaluating the results. Coverage includes laboratory principles, analytical techniques, instrumentation, analytes, pathophysiology, and more. This eighth edition features new clinical cases from The Coakley Collection, new questions from The Deacon's Challenge of Biochemical Calculations Collection, plus new content throughout the text to ensure you stay ahead of all the latest techniques, instrumentation, and technologies. Condensed version of the clinical chemistry "bible" offers the same authoritative and well-presented content in a much more focused and streamlined manner. Coverage of analytical techniques and instrumentation includes optical techniques, electrochemistry, electrophoresis, chromatography, mass spectrometry, enzymology, immunochemical techniques, microchips, automation, and point of care testing. Updated chapters on molecular diagnostics cover the principles of molecular biology, nucleic acid techniques and applications, and genomes and nucleic acid alterations, reflecting the changes in this rapidly evolving field. Learning objectives, key words, and review questions are included in each chapter to support learning. More than 500 illustrations plus easy-to-read tables help readers better understand and remember key concepts
This is a pocket book to assist in the interpretation of routine biochemical results. It contains comprehensive tests of causes of abnormalities and associated algorithms, that is, an aide-memoire plus flow charts to assist in diagnosis. The material is based on the author's vast experience in teaching hospitals and in providing services to general practitioners.This book, which covers all routine bichemical tests, is aimed at medical students, house officers and general practitioners.
Case Presentations in Chemical Pathology is a compilation of medical records with clinical history, diagnosis, and recommended treatment. It discusses the symptoms and causes of the disease being investigated. It provides sample of laboratory results that is correlated to a possible malady. Some of the topics covered in the book are the ethanol-related liver problem; definition of hyperprolactinaemia; explanation of abnormal plasma magnesium presence in the blood; enzyme defect in acute intermittent porphyria; causes of elevated ketones in a patient's blood and urine; and description of androgen insensitivity syndrome. The classification and clinical diagnoses of hypercalcaemia are fully covered. The definition and symptoms of Conn's syndrome are discussed in detail. The text describes in depth the causes of euthyroid hyperthyroxinaemia. The causes of hypermagnesaemia are completely presented. A chapter is devoted to the origins of respiratory alkalosis and hyponatraemia. The book can provide useful information to doctors, students, and researchers.
Clinical Chemistry is a comprehensive textbook covering the area of medical science variously known as chemical pathology, clinical chemistry, medical biochemistry and clinical biochemistry. The biochemical processes and physiological interrelationships, of tissues, organs and molecules are discussed in the context of disease processes and related to the diagnosis, monitoring, and management of disease. Also included are analytical processes, such as immunoassay, and how these relate to clinical practice. Although the emphasis of this book is clinical biochemistry, some chapters include sections on haematology, radiology and microbiology where this helps in the understanding of disease processes. The increasing use of the techniques of molecular biology and genetics in the investigation of disease is acknowledged also by appropriate inclusion of these disciplines in a number of chapters. Standard International (SI) units of measurement are used throughout, but for tests where non-SI units are in common use as well as SI units both sets of units are quoted.
