Photodynamic therapy utilizes photosensitizers together with irradiating light of specific wavelengths interacting with oxygen to generate cytotoxic reactive oxygen species, in particular singlet oxygen, for clinical treatment of several malignant and non-malignant pathologies. Recently, enhanced photodynamic therapy was successfully achieved by using new light sources (i.e., light-emitting diode), novel functional nano-photosensitizers, oxygen supply and synergistic therapy. In addition, photodynamic therapy has been increasingly used in the fields of antimicrobial and antibiofilm activities. This two-volume work highlights the state-of-the-art in enhanced photodynamic therapy for clinical applications.
This Research Topic is Volume II of a series. The previous volume, which has attracted over 31k views can be found here: Smart Nanomaterials for Biosensing and Therapy Applications Medicine today faces several challenges when it comes to detecting diseases and prescribing effective treatments, which is crucial for successful disease diagnosis and treatment. Due to their unique structural and functional properties, nanomaterials, which have high surface areas and nanoscale sizes, are gaining wide attention and interest in bioengineering and biotechnology. Compared with bulk materials and molecular molecules, smart nanomaterials with special optical, magnetic, electrical and mechanical properties have shown great potential for biosensing and therapy applications. The development of these smart nanomaterials has created powerful and promising tools to address challenges in conventional diagnostic and therapeutic approaches, such as the lack of diagnostic accuracy and therapeutic efficiency. In the recent past, advances in smart nanomaterials and medical research have opened new possibilities for disease diagnosis and treatment.
The second volume of the ultimate reference on the science and applications of aggregation-induced emission The Handbook of Aggregation-Induced Emission explores foundational and advanced topics in aggregation-induced emission, as well as cutting-edge developments in the field, celebrating twenty years of progress and achievement in this important and interdisciplinary field. The three volumes combine to offer readers a comprehensive and insightful interpretation accessible to both new and experienced researchers working on aggregation-induced emission. In Volume 2: Typical AIEgens Design, the editors address the design and synthesis of typical AIEgens that have made significant contributions to aggregation-induced emission research. Recent advances in the development of aggregation-induced emission systems are discussed and the book covers novel aggregation-induced emission systems in small molecule organogels, polymersomes, metal-organic coordination complexes and metal nanoclusters. Readers will also discover: A thorough introduction to the synthesis and applications of tetraphenylpyrazine-based AIEgens, AIEgens based on 9,10-distyrylanthracene , and the Salicylaldehyde Schiff base Practical discussions of aggregation-induced emission from the sixth main group and fluorescence detection of dynamic aggregation processes using AIEgens Coverage of cyclic triimidazole derivatives and the synthesis of multi-phenyl-substituted pyrrole based materials and their applications Perfect for academic researchers working on aggregation-induced emission, this set of volumes is also ideal for professionals and students in the fields of photophysics, photochemistry, materials science, optoelectronic materials, synthetic organic chemistry, macromolecular chemistry, polymer science, and biological sciences.
This book, Proceedings of the ICR ́22 International Conference on Innovations in Computing Research, provides an essential compilation of relevant and cutting-edge academic and industry work on key computer and network security, smart cities, smart energy, IoT, health informatics, biomedical imaging, data science and computer science and engineering education topics. It offers an excellent professional development resource for educators and practitioners on the state-of-the-art in these areas and contributes towards the enhancement of the community outreach and engagement component of the above-mentioned areas. Various techniques, methods, and approaches adopted by experts in these fields are introduced. This book provides detailed explanation of the concepts that are pertinently reinforced by practical examples, and a road map of future trends that are suitable for innovative computing research. It is written by professors, researchers, and industry professionals with long experience in these fields to furnish a rich collection of manuscripts in highly regarded topics that have not been creatively compiled together before. This book can be a valuable resource to university faculty, students to enhance their research work and as a supplement to their courses in these fields, researchers, and industry professionals. Furthermore, it is a valuable tool to experts in these areas to contribute towards their professional development efforts.
Recent Advances in Analytical Techniques is a collection of updates in techniques used in chemical analysis. This volume presents information about a selection of analytical techniques. Readers will find information about: - New methods of sample preparation in biological and environmental analysis - Developments in electrochemical sensors - In vivo cytometry for detection of tumor cells - Flow discharge spectroscopy for depth profile analysis - Advances in photodynamic therapy - New methods to analyze volatility in alcoholic beverages
With today's focus on targeted and minimally invasive therapies, photodynamic therapy (PDT) is now being studied and used to combat many disease states and to investigate critical biological questions. This groundbreaking resource brings you the latest advances in photodynamic therapy and offers you a solid understanding of the design, delivery and dosimetry of the three basic ingredients of PDT - photosensitizers, light and oxygen. The book covers novel areas of mechanistic and innovative translational approaches. Moreover, it gives you an overview of the important medical applications of PDT, including approved treatments, clinical trials, and investigated therapies for cancer and non-malignant diseases.
The third volume of the ultimate reference on the science and applications of aggregation-induced emission The Handbook of Aggregation-Induced Emission explores foundational and advanced topics in aggregation-induced emission, as well as cutting-edge developments in the field, celebrating twenty years of progress and achievement in this important and interdisciplinary field. The three volumes combine to offer readers a comprehensive and insightful interpretation accessible to both new and experienced researchers working on aggregation-induced emission. In Volume 3: Emerging Applications, the editors address the applications of AIEgens in several fields, including bio-imaging, fluorescent molecular switches, electrochromic materials, regenerative medicine, detection of organic volatile contaminants, hydrogels, and organogels. Topics covered include: AIE-active emitters and their applications in OLEDs, and circularly polarized luminescence of aggregation-induced emission materials AIE polymer films for optical sensing and energy harvesting, aggregation-induced electrochemiluminescence, and mechanoluminescence materials with aggregation-induced emission Dynamic super-resolution fluorescence imaging based on photoswitchable fluorescent spiropyran Visualization of polymer microstructures Self-assembly of micelle and vesicles New strategies for biosensing and cell imaging Perfect for academic researchers working on aggregation-induced emission, this set of volumes is also ideal for professionals and students in the fields of photophysics, photochemistry, materials science, optoelectronic materials, synthetic organic chemistry, macromolecular chemistry, polymer science, and biological sciences.
This handbook presents the most recent technological advances and applications in the areas of biomedical photonics. This second edition contains introductory material and covers the state-of-the-art methods and instrumentation for biomedical photonic technologies. It integrates interdisciplinary research and development critically needed for scientists, engineers, manufacturers, teachers, students, and clinical providers to learn about the most recent advances and predicted trends in instrumentation and methods as well as clinical applications in important areas of biomedical photonics. Extensive references are provided to enhance further study.
Photodynamic therapy is a proven effective treatment of actinically damaged skin cells, nonmelanoma skin cancers, and acne and other pilosebaceous conditions. As an agent for general facial rejuvenatin it has untapped potential. The current state of PDT therapy and future applications are discussed in detail in this exciting new volume. Throughout, the focus is on evidence-based clinical uses of PDT, including pretreatment regimens, avoidance and management of complications, and posttreatment suggestions.
