Engineering Biology for Microbial Biosynthesis of Plant-Derived Bioactive Compounds
Engineering Biology for Microbial Biosynthesis of Plant-Derived Bioactive Compounds

Author: Yongjun Wei

Publisher: Elsevier

Published: 2024-03-01

Total Pages: 383

ISBN-13: 0443155593

DOWNLOAD EBOOK

Many plant-derived bioactive compounds are the foundation effective drugs to cure diseases. Usually, the bioactive compounds in plant biomass are low, and the extraction of bioactive compounds from plants is not eco-friendly, which limits their application in drugs and other industries. With the development of synthetic biology and green biomanufacturing, the biosynthesis of complex bioactive compounds is possible. However, the engineering fundamentals for microbial biosynthetic of plant-derived bioactive compounds is vast. Engineering biology for microbial biosynthesis of plant-derived bioactive compounds summarizes the engineering fundamental biotechnologies for microbial production of plant-derived bioactive compounds, allowing this content to be easily accessed. Coverage includes summaries of key achievements, identification of challenges, current approaches, tips and tricks, and helpful insights into critical bottlenecks. With a comprehensive coverage of the field, Engineering biology for microbial biosynthesis of plant-derived bioactive compounds is of great interest to undergraduate and graduate students, scientists, researchers as well as engineers who work on the microbial production of plant-derived bioactive compounds. - Provides valuable information for engineers, scientists, and industrial researchers who want to obtain microbial strains with the ability of plant-derived bioactive compound production - Guides microbial production of plant-derived bioactive compounds at the laboratory and industrial levels - Ideal resource for anyone who works on the microbial production of plant-derived bioactive compounds

Biotechnology of Bioactive Compounds
Biotechnology of Bioactive Compounds

Author: Vijai Kumar Gupta

Publisher: John Wiley & Sons

Published: 2015-04-20

Total Pages: 742

ISBN-13: 1118733495

DOWNLOAD EBOOK

Bioactive compounds play a central role in high-value product development in the chemical industry. Bioactive compounds have been identified from diverse sources and their therapeutic benefits, nutritional value and protective effects in human and animal healthcare have underpinned their application as pharmaceuticals and functional food ingredients. The orderly study of biologically active products and the exploration of potential biological activities of these secondary metabolites, including their clinical applications, standardization, quality control, mode of action and potential biomolecular interactions, has emerged as one of the most exciting developments in modern natural medicine. Biotechnology of Bioactive Compounds describes the current stage of knowledge on the production of bioactive compounds from microbial, algal and vegetable sources. In addition, the molecular approach for screening bioactive compounds is also discussed, as well as examples of applications of these compounds on human health. The first half of the book comprises information on diverse sources of bioactive compounds, ranging from microorganisms and algae to plants and dietary foods. The second half of the book reviews synthetic approaches, as well as selected bioactivities and biotechnological and biomedical potential. The bioactive compounds profiled include compounds such as C-phycocyanins, glycosides, phytosterols and natural steroids. An overview of the usage of bioactive compounds as antioxidants and anti-inflammatory agents, anti-allergic compounds and in stem cell research is also presented, along with an overview of the medicinal applications of plant-derived compounds. Biotechnology of Bioactive Compounds will be an informative text for undergraduate and graduate students of bio-medicinal chemistry who are keen to explore the potential of bioactive natural products. It also provides useful information for scientists working in various research fields where natural products have a primary role.

Microbial Cell Factories Engineering for Production of Biomolecules
Microbial Cell Factories Engineering for Production of Biomolecules

Author: Vijai Singh

Publisher: Academic Press

Published: 2021-02-13

Total Pages: 490

ISBN-13: 0128214783

DOWNLOAD EBOOK

Microbial Cell Factories Engineering for Production of Biomolecules presents a compilation of chapters written by eminent scientists worldwide. Sections cover major tools and technologies for DNA synthesis, design of biosynthetic pathways, synthetic biology tools, biosensors, cell-free systems, computer-aided design, OMICS tools, CRISPR/Cas systems, and many more. Although it is not easy to find relevant information collated in a single volume, the book covers the production of a wide range of biomolecules from several MCFs, including Escherichia coli, Bacillus subtilis, Pseudomonas putida, Streptomyces, Corynebacterium, Cyanobacteria, Saccharomyces cerevisiae, Pichia pastoris and Yarrowia lipolytica, and algae, among many others. This will be an excellent platform from which scientific knowledge can grow and widen in MCF engineering research for the production of biomolecules. Needless to say, the book is a valuable source of information not only for researchers designing cell factories, but also for students, metabolic engineers, synthetic biologists, genome engineers, industrialists, stakeholders and policymakers interested in harnessing the potential of MCFs in several fields. - Offers basic understanding and a clear picture of various MCFs - Explains several tools and technologies, including DNA synthesis, synthetic biology tools, genome editing, biosensors, computer-aided design, and OMICS tools, among others - Harnesses the potential of engineered MCFs to produce a wide range of biomolecules for industrial, therapeutic, pharmaceutical, nutraceutical and biotechnological applications - Highlights the advances, challenges, and future opportunities in designing MCFs

Scale-up and Chemical Process for Microbial Production of Plant-Derived Bioactive Compounds
Scale-up and Chemical Process for Microbial Production of Plant-Derived Bioactive Compounds

Author: Yongjun Wei

Publisher: Elsevier

Published: 2024-03-20

Total Pages: 273

ISBN-13: 0443155852

DOWNLOAD EBOOK

Many plant-derived bioactive compounds are the foundation for drugs or effective drugs to cure diseases. Usually, the bioactive compounds in plant biomass are low, and the extraction of bioactive compounds from plants is not eco-friendly, which limited th - Introduces the scale-up and chemical process development for microbial production of plant-derived bioactive compounds - Covers the useful and effective sustainable and commercial production of plant-derived bioactive compounds - Provides a guide for commercial production of plant-derived bioactive compounds and their uses for human welfare

Biotechnological Production of Bioactive Compounds
Biotechnological Production of Bioactive Compounds

Author: Madan L. Verma

Publisher: Elsevier

Published: 2019-07-20

Total Pages: 510

ISBN-13: 0444643249

DOWNLOAD EBOOK

Biotechnological Production of Bioactive Compounds provides insights on the most recent innovations, trends, concerns, solutions and practical challenges encountered in the fields of enzyme technology and nanobiotechnology for the production of bioactive materials with extra health benefits. As nanobiotechnology has improved the bioactive extraction process significantly, many bioactives, including bioflavonoids, omega-3 fatty acids, biopigments and low calorie sugar substitutes are a pivotal part of the food industry. The book highlights the production of extra health benefits "bioactives'' from plants and microbes and explains how the extraction efficiency of bioactives molecules improves significantly with the recent advances in nanobiotechnology. Researchers in the fields of biochemical engineering, biotechnology, bioremediation, environmental sustainability and those in pharma industries will find the information in this book very helpful and illuminating. - Outlines technological advances in bioactives extraction - Covers bioflavonoids, biopigments, omega-3-fatty acids and low sugar substitutes - Explains the mechanisms of Green cargo (biogenic nanoparticles) for the delivery of bioactive molecules

Plant-derived Natural Products
Plant-derived Natural Products

Author: Anne E. Osbourn

Publisher: Springer Science & Business Media

Published: 2009-07-07

Total Pages: 588

ISBN-13: 0387854983

DOWNLOAD EBOOK

Plants produce a huge array of natural products (secondary metabolites). These compounds have important ecological functions, providing protection against attack by herbivores and microbes and serving as attractants for pollinators and seed-dispersing agents. They may also contribute to competition and invasiveness by suppressing the growth of neighboring plant species (a phenomenon known as allelopathy). Humans exploit natural products as sources of drugs, flavoring agents, fragrances and for a wide range of other applications. Rapid progress has been made in recent years in understanding natural product synthesis, regulation and function and the evolution of metabolic diversity. It is timely to bring this information together with contemporary advances in chemistry, plant biology, ecology, agronomy and human health to provide a comprehensive guide to plant-derived natural products. Plant-derived natural products: synthesis, function and application provides an informative and accessible overview of the different facets of the field, ranging from an introduction to the different classes of natural products through developments in natural product chemistry and biology to ecological interactions and the significance of plant-derived natural products for humans. In the final section of the book a series of chapters on new trends covers metabolic engineering, genome-wide approaches, the metabolic consequences of genetic modification, developments in traditional medicines and nutraceuticals, natural products as leads for drug discovery and novel non-food crops.

Biotechnology of Natural Products
Biotechnology of Natural Products

Author: Wilfried Schwab

Publisher: Springer

Published: 2017-11-16

Total Pages: 317

ISBN-13: 3319679031

DOWNLOAD EBOOK

This text comprehensively covers the analysis, enzymology, physiology and genetics of valuable natural products used in the food industry that are attractive targets for biotechnological production. The focus is on the recent advances made to achieve this goal. This unique work is the first book to focus on biotechnological production of important natural products in food additives, fragrances and flavorings, and other bioactive compounds in food. The chapters offer a deep insight into modern research and the development of low molecular weight natural products. Biotechnology of Natural Products covers products in the Phenolic, Terpenoid, and Alkaloid categories, providing a full overview of the biotechnology of food additives and other low molecular weight natural products. Gene clustering and the evolution of pathways are covered, as well as future perspectives on the topic. Due to limited oil resources and increasing consumer demand for naturalness, bioprocesses are increasingly needed to meet these requirements. Novel sophisticated technologies have facilitated the elucidation of new chemical molecules, their biosynthetic pathways and biological functions. This book provides researchers with a full overview of the technologies and processes involved in the biotechnology of natural products.

Dictionary of Terpenoids
Dictionary of Terpenoids

Author: Connolly/Hill

Publisher: CRC Press

Published: 1991-12-12

Total Pages: 930

ISBN-13: 9780412257704

DOWNLOAD EBOOK

This "Dictionary of Terpenoids" is a useful reference for all those working in these fields The structures, bibliographies and physical properties of over 20,000 terpenoids are presented in 9,000 entries - represent the vast majority of all known natural terpenoids together with the most important semisynthetic terpenoids.