Electrophysiological Analysis of Synaptic Transmission
Electrophysiological Analysis of Synaptic Transmission

Author: Nicholas Graziane

Publisher: Springer Nature

Published: 2022-08-03

Total Pages: 283

ISBN-13: 1071625896

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This second edition volume expands on the previous edition with discussions on the latest techniques used to study synaptic transmissions. The chapters in this book are organized into six parts. Part One looks at the basic concepts, such as extracellular and intracellular recordings, and spatiotemporal effects of synaptic currents. Part Two describes the recording of synaptic currents, such as measuring kinetics of synaptic current and measuring reversal potentials. Part Three discusses basic experimentations of synaptic transmission and covers run-up and run-down, and amplitude. Parts Four and Five cover experimentations with computational components and molecular and visual components, such as measurement of a single synapse and electrophysiological and visual tags. Part Six explores in vivo recordings and talks about general considerations for in vivo exploration of synaptic plasticity. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Authoritative and thorough, Electrophysiological Analysis of Synaptic Transmission, Second Edition is a valuable resource that introduces graduate students and postdoctoral fellows to important topics in this field and also expands these topics to practical electrophysiological approaches.

Synaptic Modifications and Memory
Synaptic Modifications and Memory

Author: L. L. Voronin

Publisher: Springer

Published: 1993-05-27

Total Pages: 332

ISBN-13:

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Understanding of memory and learning is one of the major goals of neuroscientists and psychologists. The author first introduces the reader into the current state of knowledge of the mechanisms underlying memory by providing extensive reviews of contemporary results including behavioural approaches and molecular studies. He presents results of his group obtained by analysing elec- trical activity - including single neuron meassures. As a major experimental model the phenomenon of hippocampal long- term potentiation was studied. The so-called quantal analy- sis - a quantitative method - was applied to study mammalian brain plasticity. Short- and long-term synaptic plasticities were registered both in vivo and in vitro mammalian brain preparations. Results show the involvement of mainly presynaptic location in memory, however, the possible involvement of postsynaptic mechanisms is indicated by changes in quantal amplitude as shown by the author.

Sensory Hair Cells
Sensory Hair Cells

Author: Georgij N. Akoev

Publisher: Springer

Published: 2011-11-22

Total Pages: 0

ISBN-13: 9783642779213

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This monograph summarizes the results of the authors' own in- vestigations as well as relevant literature data about the mechanism of synaptic transmission in sensory hair cells of the acousticolater- al system. It deals mainly with primary processes in hair cells. Ad- ditionally, data on the properties and selectivity of various ionic channels are presented, with data concerning the mechanism of release of the neurotransmitter from the hair cell and the proper- ties of postsynaptic responses of afferent fibres. The role of ex- citatory amino acids in synaptic transmission is analyzed. This book gives a comprehensive overview of current research on synaptic transmission in sensory hair cells, which should be valuable to both those in the field and neuroscientists of various disciplines. St. Petersburg, January 1993 G.N. Akoev G. N. Andrianov Table of Contents Introduction ...................................... . Chapter 1 Anatomy of the Mecha- and Electroreceptors of the Acousticolateral System 3 1.1 The Organ of Corti ............................ 3 1.2 Semicircular Canals ............................ 8 1.3 The Otolith Organs ............................ 11 1.4 Lateral-Line Organs ............................ 15 1.5 Electroreceptors ............................... 20 1.5.1 Ampullary Receptors ........................... 21 1.5.2 Tuberous Receptors ............................ 26 Chapter 2 Electrophysiological Analysis of Synaptic lhlnsmission in Hair Cells ................ 33 2.1 Electrical Characteristics of Hair Cells.

An Electrophysiological Analysis of Chronic Ethanol Effects on Synaptic Distribution and Function in Rat Hippocampus
An Electrophysiological Analysis of Chronic Ethanol Effects on Synaptic Distribution and Function in Rat Hippocampus

Author: Wickliffe Abraham

Publisher:

Published: 2019-12-08

Total Pages: 158

ISBN-13: 9780530018683

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Abstract: This is a PhD thesis that investigated how chronic ethanol consumption by rats, followed by 2 months of abstinence, affected the functional connectivity of several pathways in the hippocampus. The techniques entailed field potential electrophysiology in anesthetized animals, which was used to investigate basal synaptic transmission, short-term plasticity and long-term potentiaton. Connectivity patterns were assessed using current source density analyses of depth profile data. The findings have been published as 4 papers in 1981, 1982, 1984. Dissertation Discovery Company and the University of Florida are dedicated to making scholarly works more discoverable and accessible throughout the world. This dissertation, "An Electrophysiological Analysis of Chronic Ethanol Effects on Synaptic Distribution and Function in Rat Hippocampus" by Wickliffe Carson Abraham, was obtained from the University of Florida and is being sold with permission from the author. A free digital copy of this work may also be found in the university's institutional repository, the IR@UF. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation.

Electrophysiological Analysis of the Synaptic Vesicle Priming Process
Electrophysiological Analysis of the Synaptic Vesicle Priming Process

Author: Dennis Bernd Nestvogel

Publisher:

Published: 2017

Total Pages: 0

ISBN-13:

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Chemical synaptic transmission is the most prominent communication channel employed by neural circuits. It is initiated by the action potential triggered fusion of transmitter-filled synaptic vesicles with the presynaptic plasma membrane. Proteins of the CAPS and Munc13 families are required to prime synaptic vesicles for fusion before these can release their contents into the synaptic cleft. In the present study, I dissected the functional interplay of both protein families during the priming process and furthermore tested the significance of two recently described presynaptic proteins in ...

Electrophysiology
Electrophysiology

Author: D. I. Wallis

Publisher:

Published: 1993

Total Pages: 326

ISBN-13:

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Electrophysiological techniques are vital to modern biology in general and are of particular significance in neuroscience. This volume provides a practical introduction to the methods used for studying single cells and complex neural tissues. Detailed advice is given not only for handling and culturing neural tissues and cells, but also for the mathematical approaches to modeling neuronal behavior and analysing the quantal release of neurotransmitters. An important sourcebook of protocols, helpful hints, and expert advice, it will prove invaluable to researchers in neuroscience, physiology, cell biology, and related areas.