Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury, 5
Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury, 5

Author: Kenneth V. Honn

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 592

ISBN-13: 1461501938

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This volume represents a collection of contributions from the 6th International Conference on Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Related Diseases held in Boston from September 12-15, 1999. The mission of this meeting was to bring together senior and junior investigators to both announce and examine their recent advancements in cutting-edge research on the roles and actions of lipid mediators and their impact in human physiology and disease pathogenesis. The meeting focused on new concepts in these areas of interest to both clinicians and researchers. The program included several outstanding plenary lectures and presentations by leading experts in the fields of cancer and inflammation. In addition, the Boston meeting presented three Young Investigator awards, one in each of the major focus areas. The meeting was exciting and proved to be very memorable. The program was developed with an emphasis on recent advances in molecular and of lipid mediators relevant in cellular mechanisims involved in the formation and actions inflammation and cancer. Plenary lectures were presented by Prof. Bengt Sammuelsson (Karolinska Institute, Stockholm; 1982 Nobel Laureate in Physiology or Medicine) and Prof. E. 1. Corey (Harvard University; 1990 Nobel Laureate in Chemistry). Both of these plenary lectures were held on Day 1, which set an exciting tone for this meeting. Immediately following these plenary lectures, three simultaneous breakout sessions were held, one of inflammation, a second on cancer and synthesis of novel inhibitors, and a third on enzymes-lipoxygenases/cyclooxygenases and inhibitors.

Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation and Radiation Injury
Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation and Radiation Injury

Author: Santosh Nigam

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 765

ISBN-13: 1461535204

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In recent decades eicosanoids have been attracting an increasing amount of attention as a result of their important physiological roles in many areas of biology and medicine. The eicosanoids comprise the prostaglandins, thromboxanes and leukotrienes and are products of arachidonic acid, an essential polyunsaturated fatty acid stored in tissue phospholipids. Disturbances of eicosanoids and their metabolic products play a regulatory role in many types of cell injuries and diseases. One of the most exciting areas of eicosanoid research pinpoints their participation in the control of cell proliferation and differentiation. Eicosanoids form a link between different fields of research into such areas as cancer, inflammation and radiation-induced injury. This link provided the impetus for the development of the conference series of which the present volume represents the proceedings of the Second International Conference, held in Berlin in October 1991.

Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 2
Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 2

Author: Kenneth V. Honn

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 542

ISBN-13: 1461553253

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Over one hundred contributions detail advances in the molecular and cellular biology of eicosanoid production, as well as their role in signal transduction. One of the most exciting developments explored within this collection of articles is the expression of the novel isoform of cyclooxygenase (cox-2), which may play a large role in the development of anti-inflammatory drugs.

Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 2
Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 2

Author: Kenneth V. Honn

Publisher: Springer

Published: 1998-02-28

Total Pages: 555

ISBN-13: 9780306453601

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Over one hundred contributions detail advances in the molecular and cellular biology of eicosanoid production, as well as their role in signal transduction. One of the most exciting developments explored within this collection of articles is the expression of the novel isoform of cyclooxygenase (cox-2), which may play a large role in the development of anti-inflammatory drugs.

Pediatric Gender Assignment
Pediatric Gender Assignment

Author: Stephen A. Zderic

Publisher: Springer Science & Business Media

Published: 2003-01-31

Total Pages: 334

ISBN-13: 9780306467592

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This book represents the proceedings from a conference that took place in Dallas in the spring of 1999 which was entitled "Pediatric Gender Assignment - A Critical Reappraisal". Some participants rightfully argued that the conference really focused on the issue of pediatric gender assignment, and that reassignment was not applied in most cases. Their comments were reflected in the title of this monograph. This multidisciplinary meeting was sponsored by a conference grant from the National Institutes of Health, and a broad inquiry into this complex topic took place from many points of view. Basic scientists offered insight into mechanisms of sexual differentiation of the gonads, physical phenotype and imprinting of the central nervous system. Endocrinologists reviewed their experience in diagnosis and management, surgeons described traditional as well as innovative approaches, and there was strong representation from the ethical and behavioral sciences. In putting together such a panel, it was essential that we identify a cast of speakers who could address their viewpoints with strong convictions, and yet not let their passions render the meeting counter productive. We were not disappointed. While many differing points of view were firmly expressed by the panelists and audience, all viewpoints were accorded the respect they deserved. The concept behind the meeting and this book really originated in 1997 shortly after Diamond and Sigmundson published their long term follow up study of the John/Joan case.

Natural Products Targeting Clinically Relevant Enzymes
Natural Products Targeting Clinically Relevant Enzymes

Author: Paula B. Andrade

Publisher: John Wiley & Sons

Published: 2017-12-04

Total Pages: 348

ISBN-13: 3527342052

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The past decade has seen the reappearance of natural products as a valuable source of potent therapeutics. Here, experts on bioactive natural products cover the full spectrum of clinically relevant enzymes that are known to be targeted by natural products. Key enzymes include acetylcholine esterase, angiotensin-I-converting enzyme, cyclooxygenase, dihydrofolate reductase, phospholipase A2, respiratory complexes, and many more. By connecting the diversity of medicinal natural product sources with their potential clinical applications, this volume serves as a companion for the medicinal chemist looking for innovative small molecule compounds as well as for pharmacologist interested in the clinical effects and mode of action of herbal and traditional medicines.

Current Catalog
Current Catalog

Author: National Library of Medicine (U.S.)

Publisher:

Published: 1993

Total Pages: 704

ISBN-13:

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First multi-year cumulation covers six years: 1965-70.