Pulmonary Gas Exchange

Pulmonary Gas Exchange

Author: G. Kim Prisk

Publisher: Biota Publishing

Published: 2013-08-01

Total Pages: 88

ISBN-13: 1615044515

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The lung receives the entire cardiac output from the right heart and must load oxygen onto and unload carbon dioxide from perfusing blood in the correct amounts to meet the metabolic needs of the body. It does so through the process of passive diffusion. Effective diffusion is accomplished by intricate parallel structures of airways and blood vessels designed to bring ventilation and perfusion together in an appropriate ratio in the same place and at the same time. Gas exchange is determined by the ventilation-perfusion ratio in each of the gas exchange units of the lung. In the normal lung ventilation and perfusion are well matched, and the ventilation-perfusion ratio is remarkably uniform among lung units, such that the partial pressure of oxygen in the blood leaving the pulmonary capillaries is less than 10 Torr lower than that in the alveolar space. In disease, the disruption to ventilation-perfusion matching and to diffusional transport may result in inefficient gas exchange and arterial hypoxemia. This volume covers the basics of pulmonary gas exchange, providing a central understanding of the processes involved, the interactions between the components upon which gas exchange depends, and basic equations of the process.


Energetics of Muscular Exercise

Energetics of Muscular Exercise

Author: Guido Ferretti

Publisher: Springer

Published: 2015-03-25

Total Pages: 196

ISBN-13: 3319056360

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This book discusses the maximal power and capacity of the three major biochemical pathways - aerobic (oxygen consumption), anaerobic lactic (muscle lactate accumulation in absence of oxygen consumption), and anaerobic alactic (phosphocreatine hydrolysis) metabolism - as well as the factors that limit them. It also discusses the metabolic and cardio-pulmonary mechanisms of the dynamic response to exercise. The way and extent to which the power and capacity of the three major energy metabolisms are affected under a number of different conditions, such as training, hypoxia and microgravity, are also described.


Regulation of Coronary Blood Flow

Regulation of Coronary Blood Flow

Author: Michitoshi Inoue

Publisher: Springer Science & Business Media

Published: 2013-11-09

Total Pages: 330

ISBN-13: 4431683674

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Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.


Respiratory Control

Respiratory Control

Author: F.S. Grodins

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 456

ISBN-13: 1461305292

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The fourth Oxford Conference entitled "Control of Breathing: A Model ing Perspective" was held in September of 1988 at Grand Lake, Colorado. Grand Lake, also called Spirit Lake, was chosen for the fourth meet i ng so as to continue the meditative atmosphere of the previ ous meetings and to put the conference on a new higher plane (8,500 feet). The weather, as promised, exhibited its random-like rain showers. The snow report became essential for traveling the 12,000 foot passes to and from Grand Lake. Even the servi ces such as telephone and elect ri city proved to be uncertain. In all, the overall atmosphere of Spirit Lake contributed to an uninhibited free-style of presentation and interaction. All of us who attend the Oxford Conferences share a common interest in exploring respiratory control and the regulation of breathing. Modeling has become an adjunct to our exploration process. For us, models are tools that extend our ability to conceptualize just as instruments are tools that extend our ability to measure. And so these meetings attract physicians, physiologists, mathematicians and engineers who are modelers and modelers who are engineers, mathematicians, physiologists and physicians. Four of these physician-modelers have now passed away. They have been very important mentors for many of us. J. W. Bellville was my Ph.D. dissertation advisor at Stanford who introduced me to the intrigue of respiratory control. G. F. Filley was my colleague at the University of Colorado who enhanced my thinking about respiratory control. E. S.


Wasserman & Whipp's: Principles of Exercise Testing and Interpretation: Including Pathophysiology and Clinical Applications

Wasserman & Whipp's: Principles of Exercise Testing and Interpretation: Including Pathophysiology and Clinical Applications

Author: Kathy E Sietsema

Publisher: Lippincott Williams & Wilkins

Published: 2020-07-02

Total Pages: 1350

ISBN-13: 1975136454

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Thoroughly revised and updated for today’s clinicians, Wasserman & Whipp’s Principles of Exercise Testing and Interpretation, Sixth Edition, provides a comprehensive, practical overview of cardiopulmonary exercise testing (CPET) ideally suited for pulmonologists, cardiologists, anesthesiologists, and others with an interest in clinical exercise testing. Written by authors who are uniquely positioned to convey relevant aspects of research and apply them to clinical contexts, this volume offers in-depth coverage of essential information for conducting CPET, or for utilizing data from this discipline in clinical practice or research.


Oxygen Uptake Kinetics in Sport, Exercise and Medicine

Oxygen Uptake Kinetics in Sport, Exercise and Medicine

Author: Andrew M. Jones

Publisher: Routledge

Published: 2013-07-04

Total Pages: 433

ISBN-13: 1134404506

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Despite its crucial importance, scientists interested in the limitations of human physical performance have only just started to give the field of oxygen uptake kinetics the attention it deserves. Understanding the principal determinant of the oxygen uptake kinetics is fundamental to improving human performance or the quality of life. This book provides a detailed overview of the current state of knowledge of this emerging field of study, and features: * an introduction to oxygen uptake kinetics and historical development of the discipline * measurement and analysis of oxygen uptake kinetics * control of and limitations to oxygen uptake kinetics * applications of oxygen uptake kinetics in a range of human populations. Oxygen Uptake Kinetics in Sport, Health and Medicine is richly illustrated and structured to enable easy access of information and represents an invaluable resource for students and researchers in exercise physiology, as well as for respiratory physiologists and pulmonary clinicians.


Modeling and Parameter Estimation in Respiratory Control

Modeling and Parameter Estimation in Respiratory Control

Author: M.C.K. Khoo

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 204

ISBN-13: 1461306213

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Experimentalists tend to revel in the complexity and multidimensionality of biological processes. Modelers, on the other hand, generally look towards parsimony as a guiding prin ciple in their approach to understanding physiological systems. It is therefore not surprising that a substantial degree of miscommunication and misunderstanding still exists between the two groups of truth-seekers. However, there have been numerous instances in physiology where the marriage of mathematical modeling and experimentation has led to powerful in sights into the mechanisms being studied. Respiratory control represents one area in which this kind of cross-pollination has proven particularly fruitful. While earlier modeling ef forts were directed primarily at the chemical control of ventilation, more recent studies have extended the scope of modeling to include the neural and mechanical aspects pertinent to respiratory control. As well, there has been a greater awareness of the need to incorpo rate interactions with other organ systems. Nevertheless, it is necessary from time to time to remind experimentalists of the existence of modelers, and vice versa. The 4th Annual Biomedical Simulations Resource (BMSR) Short Course was held in Marina Del Rey on May 21-22,1989, to acquaint respiratory physiologists and clinical researchers with state-of-the art methodologies in mathematical modeling, experiment design and data analysis, as well as to provide an opportunity for experimentalists to challenge modelers with their more recent findings.


Exercise in Space

Exercise in Space

Author: Stefan Schneider

Publisher: Springer

Published: 2016-05-13

Total Pages: 124

ISBN-13: 3319295713

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This volume of the Series SpringerBriefs in Space Life Sciences summarizes the newest finding in the field of mental health and physiological exercise in Space. Currently two major challenges are impacting human health in the western societies, one being a move towards a sedentary society, the second one being longevity. Both have a considerable impact on physical as well as mental health. Space life science research helps to understand the underlying degenerative physiological and neuro-psychological processes as living in space, living in microgravity can be regarded as a time lapse of the sedentary and aging human being. Translational research of the past years has shown that exercise can be regarded as a key factor to counteract physical and mental deconditioning in space, guaranteeing a holistic approach to health and a benefit to the socio-demographic changes of our society. The book is written for scientists in biomedicine, more specific in aging research, sports physiology and neurosciences.