Report
Author: United States. Congress. House
Publisher:
Published:
Total Pages: 2112
ISBN-13:
DOWNLOAD EBOOKRead and Download eBook Full
Author: United States. Congress. House
Publisher:
Published:
Total Pages: 2112
ISBN-13:
DOWNLOAD EBOOKAuthor: United States. Congress
Publisher:
Published: 1968
Total Pages: 1372
ISBN-13:
DOWNLOAD EBOOKThe Congressional Record is the official record of the proceedings and debates of the United States Congress. It is published daily when Congress is in session. The Congressional Record began publication in 1873. Debates for sessions prior to 1873 are recorded in The Debates and Proceedings in the Congress of the United States (1789-1824), the Register of Debates in Congress (1824-1837), and the Congressional Globe (1833-1873)
Author:
Publisher:
Published: 1972
Total Pages: 36
ISBN-13:
DOWNLOAD EBOOKReport for May 1963 contains revised estimates of farm-mortgage debt for the period 1950-62.
Author: Willis Fletcher Johnson
Publisher:
Published: 1920
Total Pages: 398
ISBN-13:
DOWNLOAD EBOOKAuthor: Jong Hoon Park
Publisher: Springer
Published: 2016-10-12
Total Pages: 128
ISBN-13: 9811020418
DOWNLOAD EBOOKAutosomal Dominant Polycystic Kidney Disease (ADPKD) is a highly prevalent hereditary renal disorder in which fluid-filled cysts are appeared in both kidneys. Main causative genes of ADPKD are PKD1 and PKD2, encoding for polycystin-1 (PC1) and polycystin-2 (PC2) respectively. Those proteins are localized on primary cilia and function as mechanosensor in response to the fluid flow, translating mechanistic stimuli into calcium signaling. With mutations either of PKD1 or PKD2, hyper-activated renal tubular epithelial cell proliferation is observed, followed by disrupted calcium homeostasis and aberrant intracellular cyclic AMP (cAMP) accumulation. Increased cell proliferation with fluid secretion leads to the development of thousands of epithelial-lined, fluid-filled cysts in kidneys. It is also accompanied by interstitial inflammation, fibrosis, and finally reaching end-stage renal disease (ESRD). In human ADPKD, the age at which renal failure typically occurs is later in life, however no specific targeted medications are available to cure ADPKD. Recently, potential therapeutic targets or surrogate diagnostic biomarkers for ADPKD are proposed with the advances in the understanding of ADPKD pathogenesis, and some of them were attempted for clinical trials. Herein, we will summarize genetic and epi-genetic molecular mechanisms in ADPKD progression, and overview the currently available biomarkers or potential therapeutic reagents suggested.
Author: Willis Fletcher Johnson
Publisher: Legare Street Press
Published: 2022-10-27
Total Pages: 0
ISBN-13: 9781017368840
DOWNLOAD EBOOKThis work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
Author: Nicholas C. Flemming
Publisher: John Wiley & Sons
Published: 2017-08-07
Total Pages: 552
ISBN-13: 1118922131
DOWNLOAD EBOOKQuaternary Paleoenvironments examines the drowned landscapes exposed as extensive and attractive territory for prehistoric human settlement during the Ice Ages of the Pleistocene, when sea levels dropped to 120m-135m below their current levels. This volume provides an overview of the geological, geomorphological, climatic and sea-level history of the European continental shelf as a whole, as well as a series of detailed regional reviews for each of the major sea basins. The nature and variable attractions of the landscapes and resources available for human exploitation are examined, as are the conditions under which archaeological sites and landscape features are likely to have been preserved, destroyed or buried by sediment during sea-level rise. The authors also discuss the extent to which we can predict where to look for drowned landscapes with the greatest chance of success, with frequent reference to examples of preserved prehistoric sites in different submerged environments. Quaternary Paleoenvironments will be of interest to archaeologists, geologists, marine scientists, palaeoanthropologists, cultural heritage managers, geographers, and all those with an interest in the drowned landscapes of the continental shelf.
Author:
Publisher:
Published: 2004
Total Pages: 20
ISBN-13:
DOWNLOAD EBOOKAuthor: Chris D. Geddes
Publisher: Springer
Published: 2017-03-09
Total Pages: 305
ISBN-13: 3319502891
DOWNLOAD EBOOKFor several years, researchers have been reporting the effects of microwave radiation/heating on both the structure and function of DNA, RNA and proteins. For the most part, favourable accelerated biological functions are observed as microwave induced heating occurs, but other not-so favourable effects are also observed, such as denaturation, fragmentation and the so called and ill-explained, non-thermal microwave effects. This volume, the first of its kind, brings researchers together from around the world to discuss their current findings and thinking on the effects of Microwaves on Biological systems, particularly DNA, RNA and proteins, in the form of contributed edited chapters.