DPT Vaccine and Chronic Nervous System Dysfunction
Author:
Publisher: National Academies
Published: 1994
Total Pages: 34
ISBN-13:
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Adverse Effects of Pertussis and Rubella Vaccines
Author: Institute of Medicine
Publisher: National Academies Press
Published: 1991-02-01
Total Pages: 382
ISBN-13: 0309103681
DOWNLOAD EBOOKParents have come to depend on vaccines to protect their children from a variety of diseases. Some evidence suggests, however, that vaccination against pertussis (whooping cough) and rubella (German measles) is, in a small number of cases, associated with increased risk of serious illness. This book examines the controversy over the evidence and offers a comprehensively documented assessment of the risk of illness following immunization with vaccines against pertussis and rubella. Based on extensive review of the evidence from epidemiologic studies, case histories, studies in animals, and other sources of information, the book examines: The relation of pertussis vaccines to a number of serious adverse events, including encephalopathy and other central nervous system disorders, sudden infant death syndrome, autism, Guillain-Barre syndrome, learning disabilities, and Reye syndrome. The relation of rubella vaccines to arthritis, various neuropathies, and thrombocytopenic purpura. The volume, which includes a description of the committee's methods for evaluating evidence and directions for future research, will be important reading for public health officials, pediatricians, researchers, and concerned parents.
The National Childhood Encephalopathy Study
Author: Nicola Madge
Publisher: Cambridge University Press
Published: 1993-07
Total Pages: 126
ISBN-13: 9780521458832
DOWNLOAD EBOOKThis book presents the findings from an extensive follow-up report of 1,182 children from the National Childhood Encephalopathy Study conducted in Britain. Each of these children had an early neurological illness, and each was matched according to age, sex, and geographical location with two control children. For the present follow-up, the researchers evaluated the survival, development, and capabilities of 80% of the children from the original study. They found that the children's outcomes varied considerably: while some appeared fully recovered, others were severely impaired. The size of the study enabled the researchers to identify those factors that most reliably predicted outcome, such as early diagnosis, continuing convulsions, and age at onset of the illness, as well as those factors that did not prove predictive of outcome, such as sex and social conditions. The researchers also examined the question of whether or not early neurological illness predicted a single syndrome of subsequent impairment. They found that, on the contrary, the children displayed different patterns of longer-term difficulties. This is a special issue of Developmental Medicine and Child Neurology.
Adverse Effects of Vaccines
Author: Institute of Medicine
Publisher: National Academies Press
Published: 2012-04-26
Total Pages: 894
ISBN-13: 0309214351
DOWNLOAD EBOOKIn 1900, for every 1,000 babies born in the United States, 100 would die before their first birthday, often due to infectious diseases. Today, vaccines exist for many viral and bacterial diseases. The National Childhood Vaccine Injury Act, passed in 1986, was intended to bolster vaccine research and development through the federal coordination of vaccine initiatives and to provide relief to vaccine manufacturers facing financial burdens. The legislation also intended to address concerns about the safety of vaccines by instituting a compensation program, setting up a passive surveillance system for vaccine adverse events, and by providing information to consumers. A key component of the legislation required the U.S. Department of Health and Human Services to collaborate with the Institute of Medicine to assess concerns about the safety of vaccines and potential adverse events, especially in children. Adverse Effects of Vaccines reviews the epidemiological, clinical, and biological evidence regarding adverse health events associated with specific vaccines covered by the National Vaccine Injury Compensation Program (VICP), including the varicella zoster vaccine, influenza vaccines, the hepatitis B vaccine, and the human papillomavirus vaccine, among others. For each possible adverse event, the report reviews peer-reviewed primary studies, summarizes their findings, and evaluates the epidemiological, clinical, and biological evidence. It finds that while no vaccine is 100 percent safe, very few adverse events are shown to be caused by vaccines. In addition, the evidence shows that vaccines do not cause several conditions. For example, the MMR vaccine is not associated with autism or childhood diabetes. Also, the DTaP vaccine is not associated with diabetes and the influenza vaccine given as a shot does not exacerbate asthma. Adverse Effects of Vaccines will be of special interest to the National Vaccine Program Office, the VICP, the Centers for Disease Control and Prevention, vaccine safety researchers and manufacturers, parents, caregivers, and health professionals in the private and public sectors.
Adverse Events Associated with Childhood Vaccines
Author: Institute of Medicine
Publisher: National Academies Press
Published: 1993-01-01
Total Pages: 481
ISBN-13: 0309048958
DOWNLOAD EBOOKChildhood immunization is one of the major public health measures of the 20th century and is now receiving special attention from the Clinton administration. At the same time, some parents and health professionals are questioning the safety of vaccines because of the occurrence of rare adverse events after immunization. This volume provides the most thorough literature review available about links between common childhood vaccinesâ€"tetanus, diphtheria, measles, mumps, polio, Haemophilus influenzae b, and hepatitis Bâ€"and specific types of disorders or death. The authors discuss approaches to evidence and causality and examine the consequencesâ€"neurologic and immunologic disorders and deathâ€"linked with immunization. Discussion also includes background information on the development of the vaccines and details about the case reports, clinical trials, and other evidence associating each vaccine with specific disorders. This comprehensive volume will be an important resource to anyone concerned about the immunization controversy: public health officials, pediatricians, attorneys, researchers, and parents.
Immunization Safety Review
Author: Institute of Medicine
Publisher: National Academies Press
Published: 2003-11-26
Total Pages: 118
ISBN-13: 0309168910
DOWNLOAD EBOOKThe Immunization Safety Review Committee was established by the Institute of Medicine (IOM) to evaluate the evidence on possible causal associations between immunizations and certain adverse outcomes, and to then present conclusions and recommendations. The committee's mandate also includes assessing the broader societal significance of these immunization safety issues. While all the committee members share the view that immunization is generally beneficial, none of them has a vested interest in the specific immunization safety issues that come before the group. The committee reviews three immunization safety review topics each year, addressing each one at a time. In this fifth report in a series, the committee examines the hypothesis that exposure to polio vaccine contaminated with simian virus 40 (SV40), a virus that causes inapparent infection in some monkeys, can cause certain types of cancer.
Canadian Immunization Guide
Author: Canada. Comité consultatif national de l'immunisation
Publisher:
Published: 2006
Total Pages: 392
ISBN-13: 9780660193922
DOWNLOAD EBOOKThe seventh edition of the Canadian Immunization Guide was developed by the National Advisory Committee on Immunization (NACI), with the support ofthe Immunization and Respiratory Infections Division, Public Health Agency of Canada, to provide updated information and recommendations on the use of vaccines in Canada. The Public Health Agency of Canada conducted a survey in 2004, which confi rmed that the Canadian Immunization Guide is a very useful and reliable resource of information on immunization.
Immunization in Practice
Author:
Publisher: World Health Organization
Published: 2015
Total Pages: 292
ISBN-13: 9241549092
DOWNLOAD EBOOKThis practical guide contains seven modules targeted at district and health facility staff. It intends to meet the demands to improve immunization services so as to reach more infants in a sustainable way, building upon the experiences of polio eradication. It includes materials adapted from polio on planning, monitoring and use of data to improve the service, that can be used at any level. Revising the manual has been a team exercise. There are contributions from a large number of experts, organizations and institutions. This new edition has seven modules. Several new vaccines that have become more readily available and used in recent years have been added. Also the section on integration with other health interventions has been expanded as exciting opportunities and experiences have become evident in the years following the previous edition. Module 1: Target diseases and vaccines Module 2: The vaccine cold chain Module 3: Ensuring safe injections Module 4: Microplanning for reaching every community Module 5: Managing an immunization session Module 6: Monitoring and surveillance Module 7: Partnering with communities.
The Clinician’s Vaccine Safety Resource Guide
Author: Matthew Z. Dudley
Publisher: Springer
Published: 2018-10-27
Total Pages: 386
ISBN-13: 3319946943
DOWNLOAD EBOOKThis book provides clinicians and their staff with essential information on the vaccines that are recommended and not recommended for their patients, the diseases these vaccines prevent, and a broad range of potential vaccine safety issues that may be brought up by their patients. Each topic, from specific vaccines to safety concerns, is covered succinctly, based upon systematic reviews of the scientific literature, with talking points to be used with patients. The organization of the information makes it easy to reference specific topics and quickly find pertinent information, with the most practical details (such as recommendations and causality conclusions) highlighted at the very beginning of the respective sections. There are also sections outlining the vaccine safety system and evidence-based strategies for how to talk with patients about vaccines. This book aims to improve the efficiency and effectiveness of clinical vaccine discussions with patients, leading to more informed patients and timely vaccination. This is an ideal resource for all clinicians administering vaccines and their healthcare teams.
Immunization Safety Review
Author: Institute of Medicine
Publisher: National Academies Press
Published: 2004-09-30
Total Pages: 214
ISBN-13: 030909237X
DOWNLOAD EBOOKThis eighth and final report of the Immunization Safety Review Committee examines the hypothesis that vaccines, specifically the measles-mumps-rubella (MMR) vaccine and thimerosal-containing vaccines, are causally associated with autism. The committee reviewed the extant published and unpublished epidemiological studies regarding causality and studies of potential biologic mechanisms by which these immunizations might cause autism. Immunization Safety Review: Vaccines and Autism finds that the body of epidemiological evidence favors rejection of a causal relationship between thimerosal-containing vaccines and autism. The book further finds that potential biological mechanisms for vaccine-induced autism that have been generated to date are only theoretical. It recommends a public health response that fully supports an array of vaccine safety activities and recommends that available funding for autism research be channeled to the most promising areas. The book makes additional recommendations regarding surveillance and epidemiological research, clinical studies, and communication related to these vaccine safety concerns.
