Read and Download eBook Full
Author: Andrew D. Bates
Publisher: Oxford University Press, USA
Published: 2005
Total Pages: 224
ISBN-13: 9780198567097
DOWNLOAD EBOOK"A key aspect of DNA is its ability to form a variety of structures, this book explains the origins and importance of such structures"--Provided by publisher.
Author: Nicholas R. Cozzarelli
Publisher:
Published: 1990
Total Pages: 504
ISBN-13:
DOWNLOAD EBOOKAuthor: Toshiwo Andoh
Publisher: CRC Press
Published: 1992-10-26
Total Pages: 400
ISBN-13: 9780849349706
DOWNLOAD EBOOKMolecular Biology of DNA Topoisomerases and Its Application to Chemotherapy is based on conference proceedings from the International Symposium on DNA Topoisomerases in Chemotherapy, held in Nagoya, Japan, in November 1991. The book opens with a discussion of the structural and functional properties of various types of DNA topoisomerases identified in prokaryotes and eukaryotes, in addition to their roles as cellular targets of anticancer and antimicrobial agents. Other topics addressed include the genetics and biology of DNA topoisomerases, inhibitors of microbial DNA topoisomerases and drug resistance, inhibitors of mammalian DNA topoisomerases and drug resistance, and preclinical and clinical studies of DNA topoisomerase inhibitors. Molecular Biology of DNA Topoisomerases and Its Application to Chemotherapy will broaden the understanding of biology and genetics of DNA topoisomerases and contribute to the development of antimicrobial and anticancer agents-inhibitors of topoisomerases. It will be invaluable for oncologists, molecular biologists, cellular biologists, geneticists, biochemists, and pharmaceutical researchers.
Author: Charles E. Swenberg
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 338
ISBN-13: 1461529182
DOWNLOAD EBOOKSpace missions subject human beings or any other target of a spacecraft to a radiation environment of an intensity and composition not available on earth. Whereas for missions in low earth orbit (LEO), such as those using the Space Shuttle or Space Station scenario, radiation exposure guidelines have been developed and have been adopted by spacefaring agencies, for exploratory class missions that will take the space travellers outside the protective confines of the geomagnetic field sufficient guidelines for radiation protection are still outstanding. For a piloted Mars mission, the whole concept of radiation protection needs to be reconsidered. Since there is an increasing interest ci many nations and space agencies in establishing a lunar base and lor exploring Mars by manned missions, it is both, timely and important to develop appropriate risk estimates and radiation protection guidelines which will have an influence on the design and structure of space vehicles and habitation areas of the extraterrestrial settlements. This book is the result of a multidisciplinary effort to assess the state of art in our knowledge on the radiation situation during deep space missions and on the impact of this complex radiation environment on the space traveller. ]t comprises the lectures by the faculty members as well as short contributions by the students given at the NATO Advanced Study Institute "Biological Effects and Physics of Solar and Galactic Cosmic Radiation" held in Armacao de Pera, Portugal, 12-23 October, 1991.
Author:
Publisher: Academic Press
Published: 1994-11-07
Total Pages: 337
ISBN-13: 008058120X
DOWNLOAD EBOOKEach volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular basis of drug action, both applied and experimental.
Author: De Witt L. Sumners
Publisher: American Mathematical Soc.
Published: 1992
Total Pages: 266
ISBN-13: 9780821855027
DOWNLOAD EBOOKGeometry and topology are subjects generally considered to be "pure" mathematics. Recently, however, some of the methods and results in these two areas have found new utility in both wet-lab science (biology and chemistry) and theoretical physics. Conversely, science is influencing mathematics, from posing questions that call for the construction of mathematical models to exporting theoretical methods of attack on long-standing problems of mathematical interest. Based on an AMS Short Course held in January 1992, this book contains six introductory articles on these intriguing new connections. There are articles by a chemist and a biologist about mathematics, and four articles by mathematicians writing about science and mathematics involved. Because this book communicates the excitement and utility of mathematics research at an elementary level, it is an excellent textbook in an advanced undergraduate mathematics course.
Author: Craig John Benham
Publisher: Springer Science & Business Media
Published: 2010-04-29
Total Pages: 359
ISBN-13: 1441906711
DOWNLOAD EBOOKPropelled by the success of the sequencing of the human and many related genomes, molecular and cellular biology has delivered significant scientific breakthroughs. Mathematics (broadly defined) continues to play a major role in this effort, helping to discover the secrets of life by working collaboratively with bench biologists, chemists and physicists. Because of its outstanding record of interdisciplinary research and training, the IMA was an ideal venue for the 2007-2008 IMA thematic year on Mathematics of Molecular and Cellular Biology. The kickoff event for this thematic year was a tutorial on Mathematics of Nucleic Acids, followed by the workshop Mathematics of Molecular and Cellular Biology, held September 15--21 at the IMA. This volume is dedicated to the memory of Nicholas R. Cozzarelli, a dynamic leader who fostered research and training at the interface between mathematics and molecular biology. It contains a personal remembrance of Nick Cozzarelli, plus 15 papers contributed by workshop speakers. The papers give an overview of state-of-the-art mathematical approaches to the understanding of DNA structure and function, and the interaction of DNA with proteins that mediate vital life processes.
Author: Alexander Vologodskii
Publisher: CRC Press
Published: 2017-11-22
Total Pages: 303
ISBN-13: 1351355821
DOWNLOAD EBOOKTopology and Physics of Circular DNA presents comprehensive coverage of the physical properties of circular DNA. The author examines how topological constraints arising from cyclization of DNA lead to distinctive properties that make closed molecules radically different from linear DNA. The phenomenon of supercoiling, its geometric and topological analysis, and the formation of noncanonical structures in circular DNA under the influence of supercoiling are emphasized. The combination of consistent theoretical analysis and detailed treatment of major experimental approaches make Topology and Physics of Circular DNA an important reference volume for biophysicists, biochemists, molecular biologists, and researchers and students who want to expand their understanding of circular DNA.
Author: David L. Nelson
Publisher: Macmillan
Published: 2008-02
Total Pages: 1303
ISBN-13: 071677108X
DOWNLOAD EBOOKAuthors Dave Nelson and Mike Cox combine the best of the laboratory and best of the classroom, introducing exciting new developments while communicating basic principles of biochemistry.
Author: Luciano Boi
Publisher: World Scientific
Published: 2011-05-19
Total Pages: 329
ISBN-13: 1908977884
DOWNLOAD EBOOKThis volume focuses on the interactions between mathematics, physics, biology and neuroscience by exploring new geometrical and topological modelling in these fields. Among the highlights are the central roles played by multilevel and scale-change approaches in these disciplines.The integration of mathematics with physics, as well as molecular and cell biology and the neurosciences, will constitute the new frontier of 21st century science, where breakthroughs are more likely to span across traditional disciplines.
