DNA Fingerprinting: Advancements and Future Endeavors

DNA Fingerprinting: Advancements and Future Endeavors

Author: Hirak Ranjan Dash

Publisher: Springer

Published: 2018-11-01

Total Pages: 321

ISBN-13: 9811315833

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This book describes the basics and various applications of DNA fingerprinting, including in actual case studies. The book is divided in four modules; Module 1: Basics of DNA Fingerprinting, Module 2: Applications of DNA Fingerprinting, Module 3: DNA Fingerprinting: Case Studies, and Module 4: Future of DNA Fingerprinting. Each module consists of 4 to 5 chapters, written by reputed researchers, academics and forensic scientists from around the globe. The respective chapters cover e.g. related fields, the tools and techniques used, various genotyping kits, real-world case studies, ancient DNA and wild life forensics, molecular diagnosis of human diseases, legal aspects, microbial forensics and the economics of the DNA fingerprinting technique. The book offers a practical guide for professionals, graduate and post-graduate students in the fields of Forensic Science, Medicine, Genetics, Anthropology, Microbiology, and Zoology. It also serves as a useful reference resource, summarizing major technological advances in the field of DNA fingerprinting, the problems faced in this field of science and possible new solutions to these problems. Presently, DNA fingerprinting is utilized in solving the majority of criminal cases; as such, the book is also helpful for investigating agencies, as it includes representative case studies.


Textbook of Forensic Science

Textbook of Forensic Science

Author: Pankaj Shrivastava

Publisher: Springer Nature

Published: 2023-10-28

Total Pages: 839

ISBN-13: 9819913772

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This textbook provides essential and fundamental information to modern forensics investigations. It discusses criminalistics and crime scene aspects, including investigation, management, collecting and packaging various types of physical evidence, forwarding, and chain of custody. It presents fundamental principles, ethics, challenges and criticism of forensic sciences and reviews the crime typologies, the correlates of crime, criminology, penology, and victimology. It provides a viewpoint on legal aspects, including types of evidence, the procedure in the court and scrutiny of the evidence and experts. The book summarizes forensic serological evidences such as blood, semen, saliva, milk-tears, sweat, vaginal fluids, urine, and sweat. It also provides an overview of forensic examination of different types of evidence and also includes comprehensive detailing of forensic ballistics including firearm classification, bullet comparison and matching. Further, it explores the examinations of drugs, chemicals, explosives, and petroleum products. It focuses on the various aspects of forensic toxicology, including the study of various poisons/toxins, associated signs and symptoms, a fatal dose /fatal period of poisons. The book also emphasizes digital and cyber forensics, including classification, data recovery tools, encryption and decryption methods, image, and video forensics. It is a useful resource for graduate and post-graduate students in the field of Forensic Science.


Forensic DNA Typing: Principles, Applications and Advancements

Forensic DNA Typing: Principles, Applications and Advancements

Author: Pankaj Shrivastava

Publisher: Springer Nature

Published: 2020-12-11

Total Pages: 673

ISBN-13: 9811566550

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The book explores the fundamental principles, advances in forensic techniques, and its application on forensic DNA analysis. The book is divided into three modules; the first module provides the historical prospect of forensic DNA typing and introduces fundamentals of forensic DNA typing, methodology, and technical advancements, application of STRs, and DNA databases for forensic DNA profile analysis. Module 2 examines the problems and challenges encountered in extracting DNA and generating DNA profiles. It provides information on the methods and the best practices for DNA isolation from forensic biological samples and human remains like ancient DNA, DNA typing of skeletal remains and disaster victim identification, the importance of DNA typing in human trafficking, and various problems associated with capillary electrophoresis. Module 3 emphasizes various technologies that are based on SNPs, STRs namely Y-STR, X-STR, mitochondrial DNA profiling in forensic science. Module 4 explores the application of non-human forensic DNA typing of domestic animals, wildlife forensics, plant DNA fingerprinting, and microbial forensics. The last module discusses new areas and alternative methods in forensic DNA typing, including Next-Generation Sequencing, and its utility in forensic science, oral microbes, and forensic DNA phenotyping. Given its scope, the book is a useful resource in the field of DNA fingerprinting for scientists, forensic experts, and students at the postgraduate level.


Next Generation Sequencing (NGS) Technology in DNA Analysis

Next Generation Sequencing (NGS) Technology in DNA Analysis

Author: Hirak Ranjan Dash

Publisher: Elsevier

Published: 2023-11-30

Total Pages: 614

ISBN-13: 032399380X

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Next Generation Sequencing (NGS) Technology in DNA Analysis explains and summarizes next generation sequencing (NGS) technological applications in the field of forensic DNA analysis. The book covers the transition from capillary electrophoresis (CE)-based technique to NGS platforms and the fundamentals of NGS technologies, applications, and advances. Sections provide an overview of NGS technology and forensic science, including information on processing biological samples for forensic analysis, sequence analysis, and data analysis software as well as the analysis of NGS data. The book explores the valuable applications of NGS-based forensic DNA analysis and covers the validations and interpretation guidelines of NGS workflows. With chapter contributions from an international array of experts and the inclusion of practical case studies, this book is a useful reference for academicians and researchers in genetics, biotechnology, bioinformatics, biology, and medicine as well as forensic DNA scientists and practitioners who aim to learn, use, apply, and validate NGS-based technologies. - Describes the fundamentals of NGS and its advances for forensic applications - Explains the transition from CE-based technique to NGS technology - Includes case studies related to NGS and DNA fingerprinting - Explores the future use and applications of NGS technologies


Technology in Forensic Science

Technology in Forensic Science

Author: Deepak Rawtani

Publisher: John Wiley & Sons

Published: 2020-08-19

Total Pages: 416

ISBN-13: 3527827676

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The book "Technology in Forensic Science" provides an integrated approach by reviewing the usage of modern forensic tools as well as the methods for interpretation of the results. Starting with best practices on sample taking, the book then reviews analytical methods such as high-resolution microscopy and chromatography, biometric approaches, and advanced sensor technology as well as emerging technologies such as nanotechnology and taggant technology. It concludes with an outlook to emerging methods such as AI-based approaches to forensic investigations.


Fisheries Biotechnology and Bioinformatics

Fisheries Biotechnology and Bioinformatics

Author: C. Judith Betsy

Publisher: Springer Nature

Published: 2023-12-13

Total Pages: 223

ISBN-13: 9819969913

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This authored book is focused on SDG 14: Life below water, comprehensively addressing all facets of biotechnology and bioinformatics related to fisheries. It offers an extensive exploration of the detail on structure, function and types of nucleic acids, concepts of gene and genetic code, mutations, and their implications. The book provides essential information on gene regulation and expression in prokaryotes and eukaryotes. Step-by-step descriptions are provided for technologies such as gene transfer, rDNA, transgenic fish production, animal cell culture, hybridoma technology and cryopreservation technology in fishes. Special emphasis has been given to topics like RNA in gene regulation, epigenetics, and DNA and protein sequencing. Various molecular techniques and markers have been discussed in detail. Further, various topics on bioinformatics including different databases, formats, sequence retrieval, manipulation, analysis, primer design, molecular visualization, genomics, and proteomics are also covered. This volume will prove invaluable to aquaculturists, equipping them with essential techniques and protocols. It constitutes essential reading for students enrolled in aquaculture or fisheries courses within tropical and sub-tropical regions.


The Oxford Handbook of Comparative Environmental Politics

The Oxford Handbook of Comparative Environmental Politics

Author: Jeannie Sowers

Publisher: Oxford University Press

Published: 2023

Total Pages: 873

ISBN-13: 0197515037

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'The Oxford Handbook of Comparative Environmental Politics' explores some of the most important environmental issues through the lens of comparative politics, including energy, climate change, food, health, urbanization, waste, and sustainability. The chapters delve into more traditional forms of comparative environmental politics (CEP) - the political economy of natural resources and the role of corporations and supply chains - while also showcasing new trends in CEP scholarship, particularly the comparative study of environmental injustice and intersectional inequities.


DNA Technology in Forensic Science

DNA Technology in Forensic Science

Author: National Research Council

Publisher: National Academies Press

Published: 1992-02-01

Total Pages: 199

ISBN-13: 0309045878

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Matching DNA samples from crime scenes and suspects is rapidly becoming a key source of evidence for use in our justice system. DNA Technology in Forensic Science offers recommendations for resolving crucial questions that are emerging as DNA typing becomes more widespread. The volume addresses key issues: Quality and reliability in DNA typing, including the introduction of new technologies, problems of standardization, and approaches to certification. DNA typing in the courtroom, including issues of population genetics, levels of understanding among judges and juries, and admissibility. Societal issues, such as privacy of DNA data, storage of samples and data, and the rights of defendants to quality testing technology. Combining this original volume with the new update-The Evaluation of Forensic DNA Evidence-provides the complete, up-to-date picture of this highly important and visible topic. This volume offers important guidance to anyone working with this emerging law enforcement tool: policymakers, specialists in criminal law, forensic scientists, geneticists, researchers, faculty, and students.


New Avenues in Drug Discovery and Bioactive Natural Products

New Avenues in Drug Discovery and Bioactive Natural Products

Author: Raja Chakraborty

Publisher: Bentham Science Publishers

Published: 2023-08-01

Total Pages: 332

ISBN-13: 981513633X

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New Avenues in Drug Discovery and Bioactive Natural Products is the second volume of the Natural Medicine book series. It is devoted to current research in drug discovery from natural sources. The volume features 13 chapters that cover modern analytical and scientific approaches. The book starts with chapters on advanced analytical and research techniques, such as genomic mining, quality control of herbal drugs, DNA fingerprinting, high-throughput screening, molecular docking and extraction techniques. The contributors provide a summary of challenges for researchers and commercial applications where possible. The book also features chapters dedicated to specific medicinal agents that target a disease (glycosides, SARS-CoV2 spike protein inhibitors, and andrographolides. The collection of important research topics in natural product chemistry aims to help the scholars and researchers in the scientific community that are involved in the extraction and development of new medicines.


The Evaluation of Forensic DNA Evidence

The Evaluation of Forensic DNA Evidence

Author: National Research Council

Publisher: National Academies Press

Published: 1996-12-12

Total Pages: 270

ISBN-13: 0309134404

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In 1992 the National Research Council issued DNA Technology in Forensic Science, a book that documented the state of the art in this emerging field. Recently, this volume was brought to worldwide attention in the murder trial of celebrity O. J. Simpson. The Evaluation of Forensic DNA Evidence reports on developments in population genetics and statistics since the original volume was published. The committee comments on statements in the original book that proved controversial or that have been misapplied in the courts. This volume offers recommendations for handling DNA samples, performing calculations, and other aspects of using DNA as a forensic toolâ€"modifying some recommendations presented in the 1992 volume. The update addresses two major areas: Determination of DNA profiles. The committee considers how laboratory errors (particularly false matches) can arise, how errors might be reduced, and how to take into account the fact that the error rate can never be reduced to zero. Interpretation of a finding that the DNA profile of a suspect or victim matches the evidence DNA. The committee addresses controversies in population genetics, exploring the problems that arise from the mixture of groups and subgroups in the American population and how this substructure can be accounted for in calculating frequencies. This volume examines statistical issues in interpreting frequencies as probabilities, including adjustments when a suspect is found through a database search. The committee includes a detailed discussion of what its recommendations would mean in the courtroom, with numerous case citations. By resolving several remaining issues in the evaluation of this increasingly important area of forensic evidence, this technical update will be important to forensic scientists and population geneticistsâ€"and helpful to attorneys, judges, and others who need to understand DNA and the law. Anyone working in laboratories and in the courts or anyone studying this issue should own this book.