While some of the most commonly investigated- and most notorious- chemicals in the world are alkaloids, many modern medicines are also based on alkaloid structures. Chemists continue to explore new synthetic routes and alkaloid derivatives in search of drug candidates for fighting disease. Drawn from the venerable Dictionary of Natural Products, th
While some of the most commonly investigated — and most notorious — chemicals in the world are alkaloids, many modern medicines are also based on alkaloid structures. Chemists continue to explore new synthetic routes and alkaloid derivatives in search of drug candidates for fighting disease. Drawn from the venerable Dictionary of Natural Products, the second edition of the Dictionary of Alkaloids categorizes all known alkaloids, presenting concise chemical, structural, and physical data. The addition of an authoritative foreword, written by Geoffrey Cordell, eminent alkaloid chemist and Editor-in-Chief of the prestigious series The Alkaloids, Chemistry and Biology, sets the scene for this fascinating subject. Now More than Double the Size of the Previous Edition The dictionary embraces a wide definition of alkaloid so that non-basic alkaloidal amides are also comprehensively covered. Grown in number from the prior edition, the number of alkaloids documented is now more than doubled to over 20,000. For this new edition, every existing entry has been inspected for accuracy and the great majority are updated. The extensive introduction has been completely rewritten and expanded to give a concise, authoritative, and fully referenced account of the different types of alkaloids. The editorial team has been enhanced by the addition of Professor László Szabó, a renowned expert on the indole alkaloids. The presentation and classification of this large and complex class of alkaloids has been completely revamped. Reflects Groundbreaking New Developments in the Field Some notable shifts in emphasis reflect the changes in the field since the first edition was published in 1989. The main areas of new information concern novel and improved synthetic methods, and the isolation of new alkaloids of unprecedented structure from a variety of organisms, some of them resulting from the participation of newly recognized enzyme types, such as the Diels-Adler enzymes. The text also reflects new understanding of the interrelatedness of ecosystems and the way in which alkaloids and other metabolites may be passed to and metabolized by predators. An important feature of the dictionary is its classification scheme for Type of Compound. These codes are designed to complement substructure searching. Each heading merges all of the alkaloids thought by specialists to be bio-genetically related, even those that don’t share the same carbon skeleton. Includes a Fully Searchable CD-ROM Accompanying this dictionary is a fully searchable CD-ROM. The two media offer the luxury of choice between the sophisticated and user-friendly search possibilities presented in the electronic version or the ability to thumb through the highly browsable print version. Either way, readers will find access to data unparalleled both in scope and depth.
The first of its kind, this dictionary defines more than 25,000 marine- natural products. It indexes each by chemical name, organism type, and compound type. Following a similar format to the Chapman & Hall Chemical Database, each entry includes biological source, chemical structure, physical properties, biological activity, and literature references. With an accompanying CD, this invaluable tool offers immediate access to information essential to the development of novel pharmaceuticals, pesticides, and marine anti-fouling agents derived from unique molecular structures of marine natural products.
CHOICE Award Winner Since the first publication in 1995, the Organic Chemist’s Desk Reference has been essential reading for laboratory chemists who need a concise guide to the essentials of organic chemistry — the literature, nomenclature, stereochemistry, spectroscopy, hazard information, and laboratory data. The past fifteen years have witnessed immense growth in the field of chemistry and new discoveries have continued to shape its progress. In addition, the distinction between organic chemistry and other disciplines such as biochemistry and materials science has become increasingly blurred. Extensively revised and updated, this new edition contains the very latest data that chemists need access to for experimentation and research. New in the Second Edition: Rearranged content placed in a logical progressive order, making subjects easier to find Expanded topics from the glossary now presented as separate chapters Updated information on many classic subjects such as mass spectrometry and infrared, ultraviolet, and nuclear magnetic resonance spectroscopy New sections on chiral separations and crystallography Cross references to a plethora of web information Reflecting a 75% revision since the last edition, this volume is a must-have for organic chemists and those in related fields who need quick and easy access to vital information in the lab. It is also a valuable companion to the Dictionary of Organic Compounds, enabling readers to easily focus in on critical data.
Widely distributed throughout plant families, flavonoids give many flowers and fruits their vibrant colors. They also play a role in protecting the plants from microbe and insect attacks. More importantly, the consumption of foods containing flavonoids has been linked to numerous health benefits. Recent research indicates that flavonoids can be nutritionally helpful by triggering enzymes that reduce the risk of certain cancers, heart disease, and age-related degenerative diseases. Foods that contain high amounts of flavonoids include blueberries, red beans, cranberries, and blackberries. Many other foods, including red and yellow fruits and vegetables and some nuts, as well as red wine and certain teas are also rich in flavonoids. Due the potential health benefits, research into flavonoids and their potential beneficial effects on human health continues unabated. Dictionary of Flavonoids with downloadable resources lists all known flavonoids (approximately 13,000) in a single volume. It details chemical structures, physical properties, and biological source, and also includes a concise bibliography. Derived from the well-respected Dictionary of Natural Products, it is presented in a compact dictionary format, and is an invaluable reference source for all those working in this area. The book is accompanied by downloadable resources that are fully searchable by chemical structure as well as by physical properties and chemical names. Organized in alphabetical order, each page is packed with authoritative information that readers can easily access. The book and downloadable resource combination gives researchers powerful tools for unlocking and utilizing the secrets held within the colors of the plant kingdom.
Bacterial and parasitic diseases are the second leading cause of death worldwide, according to a report by the London School of Economics. Due to the emergence of drug-resistant "superbugs," like methicillin-resistant Staphylococcus aureus (MRSA), traditional antibiotics such as penicillin and its derivatives are in danger of becoming obsolete. In
Written by a group of experts affiliated with the prestigious Dictionary of Natural Products, this book provides a concise overview of the key structural types of natural products and their interrelationship. A structurally diverse group, ranging from simple aliphatic carbon chains to high molecular weight proteins, natural products can usually be classified into one or more groups. The text describes these major types, including flavonoids, carbohydrates, terpenoids, polyketides, and lipids, and it illustrates them with accurate chemical structures, demonstrating the biosynthetic relationships between groups. The book also covers nomenclature, stereochemistry, and ring numbering.
The increasing world population, competition for arable land and rich fishing grounds, and environmental concerns mandate that we exploit in a sustainable way the earth's available plant and animal resources for human consumption. To that end, food chemists, technologists, and nutritionists engage in a vast number of tasks related to food availabil
Dictionary of Toxicology, Third Edition presents a compendium of definitions of all current toxicological terminology. This authoritative reference illustrates and describes words, concepts, acronyms and symbols for both the toxicological theory and applied risk assessment, as well as providing guidance on the correct selection of problematic, similar and frequently-misused terms. Written by one of the world's foremost experts in toxicology, and with each entry peer reviewed, Dictionary of Toxicology, Third Edition is an essential reference for all scientific, medical and legal professionals who work with or encounter the toxicological effects of contaminants on biological systems. New to this edition: an update on every entry and the inclusion of all terminology and concepts relating to molecular toxicology, nanotoxicology and computational toxicology. - Presents peer-reviewed definitions on the most up-to-date toxicological terms and concepts. - New edition includes definitions within the fields of molecular toxicology, nanotoxicology, computational toxicology and risk assessment.
