Diabetes and Diabetic Complications

Diabetes and Diabetic Complications

Author: Randhir Singh Dahiya

Publisher: Nova Science Publishers

Published: 2021

Total Pages: 492

ISBN-13: 9781536194531

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"Diabetes mellitus is one of the major causes of morbidity and mortality in the modern world. Persistent hyperglycaemia is responsible for several complications of diabetes, such as diabetic retinopathy, diabetic nephropathy, diabetic neuropathy, diabetic cardiomyopathy, diabetic autonomic neuropathy, diabetic ketoacidosis, diabetic foot ulcer, gestational diabetes, and diabetic mastopathy. With the advancement of technology, several new drugs have been developed for treatment of diabetes and diabetic complications. Moreover, alternative and complementary medicines have also been employed to manage diabetes and its associated complications. Despite the availability of a plethora of therapeutic agents, the management of diabetes and diabetic complications is an uphill battle associated with several limitations. Various leading research groups across the world are investing billions of dollars to develop impeccable solutions for the treatment of diabetes and diabetic complications. This book focuses on the understanding of recent advancements in the pathogenesis of diabetes and diabetic complications, the molecular basis of the disease and recent advancements in diabetic treatment. The chapters are specifically dedicated to different complications associated with diabetes. Moreover, recent advances in treatments and medications in clinical trials for these complications are explained. Some chapters are dedicated to the use of herbal medicines, alternative and complementary therapy and personalized medicines. Furthermore, the role of epigenetics in diabetic complications is described, as well as the role of antidiabetic drugs and their interactions. Due to its widespread prevalence, diabetes is presently considered a pandemic. This book provides contemporary information to researchers and health care practitioners about diabetes and diabetic complications, which may pave the way for designing new strategies to manage diabetes and diabetic complications. Moreover, the insights on alternative and complementary medicines will help in providing a background for inclusion of these medicines as an important therapeutic option for treatment of diabetes"--


Diabetes Complications, Comorbidities and Related Disorders

Diabetes Complications, Comorbidities and Related Disorders

Author: Enzo Bonora

Publisher: Springer

Published: 2020-04-01

Total Pages: 0

ISBN-13: 9783030366933

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This book provides the reader with comprehensive information on the interactions between diabetes and a wide range of comorbid conditions and on disease management in such patients. It has the aim of empowering health care providers in their daily battle against the disease and its consequences. Diabetes has been identified by WHO and the United Nations as a medical emergency because of the increase in its global prevalence, which may reach one billion in three to four decades if the trend remains unchanged. Despite improved care that is helping to prolong life, diabetes impacts substantially on the quality of life of those affected and kills or disables several million people each year. The disease is systemic because all organs, tissues, and cells suffer in the presence of hyperglycemia and are damaged by the diabetic milieu. Unfortunately, most patients with diabetes will consequently experience chronic diabetic complications. This book will be of value for all physicians and nurses who care for patients with diabetes and face the challenge of treating hyperglycemia and related acute and chronic complications.


Management of Diabetic Foot Complications

Management of Diabetic Foot Complications

Author: Clifford P. Shearman

Publisher: Springer

Published: 2015-02-04

Total Pages: 227

ISBN-13: 1447145259

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​Public and political concern about the increasing prevalence of diabetes has prompted major concern about treatment of patients with the condition. Foot complications are some of the commonest causes of hospitalisation of people with diabetes and if not treated well often lead to amputation. There is evidence that 85% of these amputations can be prevented by better understanding of the problem and by multi-disciplinary teams working more effectively together. This has been recognised and NICE have recently published guidelines on diabetic foot complications as have Diabetes UK and NHS Diabetes. These have been successful in raising awareness of the problem but the local multi-disciplinary teams need clear practical advice on how to manage the foot in diabetes and deliver high quality care. With the current interest in improving outcomes for patients with foot complications this is an ideal time to make a practical evidence-based handbook available. This book will provide clear practical guidelines on how to manage all aspects of the foot in diabetes as well as an in-depth analysis of the most recent evidence. The book will be based on care pathways with algorithms for each section so it would be of practical value in any clinic in primary or secondary care. It will appeal to a wide range of health care professionals treating people with diabetes: vascular surgeons and trainees, orthopaedic surgeons, diabetes specialist nurses, podiatrists and tissue viability nurses.​


ABC of Arterial and Venous Disease

ABC of Arterial and Venous Disease

Author: Richard Donnelly

Publisher: John Wiley & Sons

Published: 2009-04-08

Total Pages: 117

ISBN-13: 1444312405

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Structural and functional abnormalities of arteries and veinsmanifest clinically in a broad spectrum of disorders, includinganeurysmal disease, atherosclerosis, vasculitis, venousinsufficiency, microvascular complications, thrombo-embolism andlower limb ulceration. Many of these are common and/orchronic conditions which present for initial assessment by primaryhealth care workers. This new edition is a practical guide to the most commonlypresenting disorders, and provides a structured approach toclinical assessment, investigations and management. The lastfew years have seen major changes in the use of non-invasive orminimally-invasive techniques, e.g wider use of CT and MRangiography, and increasing use of percutaneous interventions forcarotid, lower limb and reno-vascular disease. The ABC of Arterial and Venous Disease (Second Edition)explains the underlying technology and the applications of newminimally-invasive methods, especially CT and MRI, and provides anup-dated, evidence-based guide to the modern day management ofpatients with common, life-threatening diseases involving differentparts of the circulation. This authoritative, full-colour, illustrated ABC is anideal reference for the primary care, non-specialist practitionerto base effective management and prevention programmes.


Diabetes and Hypertension

Diabetes and Hypertension

Author: Samy I. McFarlane

Publisher: Springer Science & Business Media

Published: 2012-10-19

Total Pages: 196

ISBN-13: 1603273573

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Diabetes and hypertension have evolved as two of the modern day epidemics affecting millions of people around the world. These two common co-morbidities lead to substantial increase in cardiovascular disease, the major cause of morbidity and mortality of adults around the world. In Diabetes and Hypertension: Evaluation and Management, a panel of renowned experts address a range of critical topics -- from basic concepts in evaluation and management of diabetes and hypertension, such as dietary interventions, to evaluation and management of secondary hypertension in clinical practice. Other chapters focus on high cardiovascular risk populations such as those with coronary heart disease, chronic kidney disease and minority patients. In addition, evolving concepts and new developments in the field are presented in other chapters, such as prevention of type 2 diabetes and the epidemic of sleep apnea and its implication for diabetes and hypertension evaluation and management. An important title covering two of the most troubling disorders of our time, Diabetes and Hypertension: Evaluation and Management will provide the busy practitioner with cutting edge knowledge in the field as well as practical information that can translate into better care provided to the high-risk population of diabetics and hypertensive patients.


Textbook of Diabetes

Textbook of Diabetes

Author: Richard I. G. Holt

Publisher: John Wiley & Sons

Published: 2017-03-06

Total Pages: 1104

ISBN-13: 1118912020

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Now in its fifth edition, the Textbook of Diabetes has established itself as the modern, well-illustrated, international guide to diabetes. Sensibly organized and easy to navigate, with exceptional illustrations, the Textbook hosts an unrivalled blend of clinical and scientific content. Highly-experienced editors from across the globe assemble an outstanding set of international contributors who provide insight on new developments in diabetes care and information on the latest treatment modalities used around the world. The fifth edition features an array of brand new chapters, on topics including: Ischaemic Heart Disease Glucagon in Islet Regulation Microbiome and Diabetes Diabetes and Non-Alcoholic Fatty Liver Disease Diabetes and Cancer End of Life Care in Diabetes as well as a new section on Psychosocial aspects of diabetes. In addition, all existing chapters are fully revised with the very latest developments, including the most recent guidelines from the ADA, EASD, DUK and NICE. Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates Via the companion website, readers can access a host of additional online materials such as: 200 interactive MCQ's to allow readers to self-assess their clinical knowledge every figure from the book, available to download into presentations fully searchable chapter pdfs Once again, Textbook of Diabetes provides endocrinologists and diabetologists with a fresh, comprehensive and multi-media clinical resource to consult time and time again.


Diabetes

Diabetes

Author: Shamim I. Ahmad

Publisher: Springer Science & Business Media

Published: 2013-04-12

Total Pages: 515

ISBN-13: 1461454417

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Diabetes is a complex disease and is also one of the most common. It is very difficult to reach an accurate estimate for the global prevalence of diabetes since the standards and methods of data collection vary widely in different parts of the world. In addition, many potential sufferers are not included in the count because according to an estimate about 50% of cases remain undiagnosed for up to 10 years. However, according to an estimate for 2010, globally, there are about 285 million people (amounting to 6.4% of the adult population) suffering from this disease. This number is estimated to increase to 439 million by 2030 if no cure is found. The general increase in life expectancy, leading to an ageing population, and the global rise in obesity are two main reasons for the increase. With the basic platform set, Editor presents his views and advice to the readers, especially to diabetic patients suffering from T2DM, on the basis of his observations and information collected from other diabetics.


Diabetes

Diabetes

Author: Kenneth M. Shaw

Publisher: John Wiley & Sons

Published: 2012-04-25

Total Pages: 355

ISBN-13: 1118367480

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This edition of Diabetes: Chronic Complications provides both the experienced and trainee endocrinologist with easy-to-read, up-to-date practical guidance on the management of the many complications that can result from the onset of diabetes, such as kidney failure, cardiovascular disease, retinal failure, and cerebrovascular disease. Reflecting the rapid developments currently taking place in the field, the second edition introduces a brand-new section on liver complications in diabetes, additional material on mental health complications in the section on diabetes and the brain, coverage of dyslipidaemia and hypertension in the section on diabetes and the heart, five MCQ's in each section to help improve clinical skills, and a case study and key points summary box in every chapter.


The Science, Etiology and Mechanobiology of Diabetes and its Complications

The Science, Etiology and Mechanobiology of Diabetes and its Complications

Author: Amit Gefen

Publisher: Academic Press

Published: 2021-04-21

Total Pages: 436

ISBN-13: 0128210710

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The Science, Etiology and Mechanobiology of Diabetes and Its Complications presents the most comprehensive synthesis of contemporary global research on diabetes, covering a novel and unique mechanobiological perspective – addressing prevention, management and treatment of tissue, organ and body system damage associated with diabetes and its complications. The book provides a unique approach to communicating diabetes-associated symptoms and opens avenues for development of novel therapeutic and preventive methods. It offers descriptive pathophysiology of diabetes and its complications with great emphasis on mechanobiology. Content coverage also includes management of tissue, organ and body system damage caused by chronic hyperglycemia. Biologists, life scientists, physicians, pharmacists, biomedical engineers, medical physicists, biomathematicians and computer scientists who are interested in the state-of-science and current challenges in the mechanobiology of diabetes should find this book very useful. Likewise, medical researchers in fields such as endocrinology, cardiovascular medicine, oncology, obesity, the immune system, inflammation and wound care and others who wish to be updated about the latest achievements in this exciting arena of research will find that information here. - Covers the state-of-knowledge in diabetes research from a mechanobiological perspective, including cell death and (neural, connective, adipose, vascular, renal etc.) tissue damage cascades and healing processes - Describes state-of-the-art technology in prevention, diagnosis, prognosis and treatment of tissue, organ and body system damage caused by chronic hyperglycemia and diabetes - Explores emerging research directions and future technology trends in the field of diabetes prevention and care, including common complications of diabetes (foot ulcers and amputation, peripheral neuropathy, retinal damage, renal damage, vascular and cardiac damage, connective tissue damage etc.) at the early stage of research and development in academia and industry


Lipoproteins in Diabetes Mellitus

Lipoproteins in Diabetes Mellitus

Author: Alicia J. Jenkins

Publisher: Springer Science & Business Media

Published: 2014-01-08

Total Pages: 468

ISBN-13: 1461475546

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Diabetes mellitus has become epidemic on a global scale, and millions of new cases are diagnosed every year. The epidemic of diabetes mellitus is expected to result in one of the steepest rises in human morbidity and mortality ever observed outside of wartime. Insulin resistance is a hallmark of pre-diabetes and type 2 diabetes mellitus, and is characterized by impaired insulin-signaling transduction. Authoritative and comprehensive, Lipoproteins in Diabetes Mellitus details the many changes wrought by insulin resistance and diabetes mellitus on lipid and lipoprotein metabolism. The book begins by summarizing the various techniques to measure lipoproteins and their subclasses. The mechanisms by which insulin resistance and diabetes mellitus increase risk for atherosclerosis, diabetic retinopathy, and diabetic nephropathy are then explored in detail. Finally, the effects of lifestyle modification and the results of clinical trials using established and investigational drugs are discussed. An invaluable contribution to the literature, Lipoproteins in Diabetes Mellitus is a comprehensive reference on the clinical and scientific aspects of lipoproteins in diabetes. It will have a long-lasting and significant effect on the medical management of people with diabetes.