Stimuli-responsive Drug Delivery Systems
Stimuli-responsive Drug Delivery Systems

Author: Amit Singh

Publisher: Royal Society of Chemistry

Published: 2018-07-09

Total Pages: 376

ISBN-13: 1788014669

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The increased understanding of molecular aspects associated with chronic diseases, such as cancer and the role of tumor microenvironment, has led to the identification of endogenous and exogenous stimuli that can be exploited to devise “stimuli-responsive” materials for site-specific drug delivery applications. This book provides a comprehensive account on the design, materials chemistry, and application aspects behind these novel stimuli-responsive materials. Setting the scene, the editors open with a chapter addressing the need for smart materials in delivery applications for therapy, imaging and disease diagnosis. The following chapter describes the key physical and chemical aspects of smart materials, from lipids to polymers to hybrid materials, providing the reader with a springboard to delve into the more application oriented chapters that follow. With in-depth coverage of key drug delivery systems such as pH-responsive, temperature responsive, enzyme-responsive and light responsive systems, this book provides a rigorous foundation to the field. A perfect resource for graduate students and newcomers, the closing chapter on regulatory and commercialization challenges also makes the book ideal for those wanting to take the next step towards clinical translation.

Drug Targeting and Stimuli Sensitive Drug Delivery Systems
Drug Targeting and Stimuli Sensitive Drug Delivery Systems

Author: Alexandru Mihai Grumezescu

Publisher: William Andrew

Published: 2018-05-21

Total Pages: 838

ISBN-13: 0128136901

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Drug Targeting and Stimuli Sensitive Drug Delivery Systems covers recent advances in the area of stimuli sensitive drug delivery systems, providing an up-to-date overview of the physical, chemical, biological and multistimuli-responsive nanosystems. In addition, the book presents an analysis of clinical status for different types of nanoplatforms. Written by an internationally diverse group of researchers, it is an important reference resource for both biomaterials scientists and those working in the pharmaceutical industry who are looking to help create more effective drug delivery systems. - Shows how the use of nanomaterials can help target a drug to specific tissues and cells - Explores the development of stimuli-responsive drug delivery systems - Includes case studies to showcase how stimuli responsive nanosystems are used in a variety of therapies, including camptothecin delivery, diabetes and cancer therapy

Stimuli-Responsive Nanocarriers
Stimuli-Responsive Nanocarriers

Author: Virendra Gajbhiye

Publisher: Academic Press

Published: 2022-01-04

Total Pages: 485

ISBN-13: 0323859046

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Stimuli-Responsive Nanocarriers: Recent Advances in Tailor-Made Therapeutics compiles dispersed knowledge into a complete and comprehensive source to help researchers understand and progress stimuli-responsive nanocarriers. The book contains recent advancements made in the field of stimuli-responsive nanocarriers with their application in controlled drug delivery against various diseases. It focuses on the design, mechanism, construction, therapeutic application and future challenges of stimuli-responsive nanocarriers which will help new researchers in designing next generation tailor-made advanced therapeutics. Finally, the book covers future aspects and challenges present in the route of development of stimuli responsive nanocarriers for disease therapeutics. Various recent advances and biomedical applications assembled in this book will guide scientists on how to design and develop novel controlled drug release systems. - Provides comprehensive knowledge of basic design, mechanism and construction of nanocarrier based stimuli-responsive drug releases - Explores various nanocarriers characteristically used in the development of stimuli-responsive drug release systems - Envisages future opportunities, challenges and implementation of nanocarrier based stimuli-responsive drug release systems in disease therapeutics

Stimuli Responsive Drug Delivery Systems
Stimuli Responsive Drug Delivery Systems

Author: Anil Bajpai

Publisher: Smithers Rapra Technology

Published: 2010

Total Pages: 0

ISBN-13: 9781847354167

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Stimuli responsive drug delivery systems have emerged as one of the most innovative classes of polymer materials of modern materials science. The polymer architectures exhibiting a large change in their physico chemical behaviors in response to minor signals from the environments have fabricated potentially useful materials for pharmaceutical and biomedical applications. The most advanced stimuli responsive drug delivery systems have also explored a new strategy to design targeted delivery systems to treat complex diseases like cancers and related tumors. Stimuli Responsive Drug Delivery Systems offers a convincing approach to understanding the basic principles of drug delivery process, their mathematical modeling, different types of drug delivery systems, various polymer systems responsive to stimuli such as swelling, pH, temperature, electric and magnetic fields, chemical agents, and more - The material covered in this book provides a wide spectrum of information - academic, research, and professional - for the biomedical, pharmaceutical and polymer chemistry communities. The book also presents the commercial scenario of drug delivery systems and highlights upcoming challenges and existing future prospects of this field. An exhaustive bibliography of the book also enables students and researchers of various disciplines to acquire additional information they may require.

Advances and Avenues in the Development of Novel Carriers for Bioactives and Biological Agents
Advances and Avenues in the Development of Novel Carriers for Bioactives and Biological Agents

Author: Manju Rawat Singh

Publisher: Academic Press

Published: 2020-04-07

Total Pages: 657

ISBN-13: 0128199180

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Advances and Avenues in the Development of Novel Carriers for Bioactives and Biological Agents provides sound data on the utility of biological and plant-based drugs and describes challenges faced in all aspects offering indispensable strategies to use in the development of bioactive medicines. Bioactive based medications are commonly used throughout the world and have been recognized by physicians and patients for their therapeutic efficacy. Bioactive formulations, including their subordinates and analogs, address 50% of all medicines in clinical practice. Novel bioactive medicine transporters can cure many disorders by both spatial and transitory approaches and have various justifications in medicinal potential. This book presents information on the utility of natural, plant, animal and bioengineered bioactive materials. It is a fundamental source of information and data for pharmacognosists, pharmaceutical analysts, drug transport scientists and pharmacologists working in bioactive medications. - Advances information on various bioactive based medications, their sources, clinical consequences and transport strategies - Illustrates diverse transport systems for bioactives and derivatives, novel techniques for formulations, targeting strategies and fundamental qualities of developed bioactive carriers, and their safety concerns and standardization - Discusses distinctive transport systems, stability, upgraded dissolvability, and enhanced bioavailability of bioactives

Stimuli Responsive Polymeric Nanocarriers for Drug Delivery Applications
Stimuli Responsive Polymeric Nanocarriers for Drug Delivery Applications

Author: Abdel Salam Hamdy Makhlouf

Publisher: Woodhead Publishing

Published: 2018-10-24

Total Pages: 640

ISBN-13: 0081019963

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Stimuli Responsive Polymeric Nanocarriers for Drug Delivery Applications: Volume Two: Advanced Nanocarriers for Therapeutics discusses, in detail, the recent trends in designing dual and multi-responsive polymers and nanoparticles for safe drug delivery. Chapters cover dual-responsive polymeric nanocarriers for drug delivery and their different stimuli, multi-responsive polymeric nanocarriers, and the therapeutic applications of stimuli-responsive polymers. With an emphasis on advanced medical applications and synergistic operational and technological methodologies for the improvement of polymers systems for the production of stimuli-responsive polymers, this book is essential reading for materials scientists and researchers working in the drug delivery and pharmaceutical industries. As innovation and development in the area of stimuli responsive polymer-based nanomaterials for drug delivery is moving fast and there is an increased global demand for biodegradable and biocompatible responsive polymers and nanoparticles for safe drug delivery, users will find this to be a timely resource. - Focusses on the most advanced technologies, recent evaluation methods, technical aspects, and advanced synthesis techniques stimuli-responsive polymers - Examines advanced medical applications of stimuli responsive polymers - Analyzes synergistic operational and technological methodologies for the improvement of polymer systems for the production of stimuli-responsive polymers in drug delivery

Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment
Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment

Author: Jorge Coelho

Publisher: Springer Science & Business Media

Published: 2013-03-15

Total Pages: 433

ISBN-13: 9400760108

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This book is part of a series dedicated to recent advances on preventive, predictive and personalised medicine (PPPM). It focuses on the theme of “Drug delivery systems: advanced technologies potentially applicable in personalised treatments”. The critical topics involving the development and preparation of effective drug delivery systems, such as: polymers available, self-assembly, nanotechnology, pharmaceutical formulations, three dimensional structures, molecular modeling, tailor-made solutions and technological tendencies, are carefully discussed. The understanding of these areas constitutes a paramount route to establish personalised and effective solutions for specific diseases and individuals.

Modeling and Control of Drug Delivery Systems
Modeling and Control of Drug Delivery Systems

Author: Ahmad Taher Azar

Publisher: Academic Press

Published: 2021-02-06

Total Pages: 410

ISBN-13: 0128211954

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Modeling and Control of Drug Delivery Systems provides comprehensive coverage of various drug delivery and targeting systems and their state-of-the-art related works, ranging from theory to real-world deployment and future perspectives. Various drug delivery and targeting systems have been developed to minimize drug degradation and adverse effect and increase drug bioavailability. Site-specific drug delivery may be either an active and/or passive process. Improving delivery techniques that minimize toxicity and increase efficacy offer significant potential benefits to patients and open up new markets for pharmaceutical companies. This book will attract many researchers working in DDS field as it provides an essential source of information for pharmaceutical scientists and pharmacologists working in academia as well as in the industry. In addition, it has useful information for pharmaceutical physicians and scientists in many disciplines involved in developing DDS, such as chemical engineering, biomedical engineering, protein engineering, gene therapy. - Presents some of the latest innovations of approaches to DDS from dynamic controlled drug delivery, modeling, system analysis, optimization, control and monitoring - Provides a unique, recent and comprehensive reference on DDS with the focus on cutting-edge technologies and the latest research trends in the area - Covers the most recent works, in particular, the challenging areas related to modeling and control techniques applied to DDS

Nanoengineering of Biomaterials
Nanoengineering of Biomaterials

Author: Sougata Jana

Publisher: John Wiley & Sons

Published: 2022-04-18

Total Pages: 1063

ISBN-13: 3527349049

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A comprehensive discussion of various types of nanoengineered biomaterials and their applications In Nanoengineering of Biomaterials: Drug Delivery & Biomedical Applications, an expert team of chemists delivers a succinct exploration of the synthesis, characterization, in-vitro and in-vivo drug molecule release, pharmacokinetic activity, pharmacodynamic activity, and the biomedical applications of several types of nanoengineered biomaterials. The editors have also included resources to highlight the most current developments in the field. The book is a collection of valuable and accessible reference sources for researchers in materials chemistry and related disciplines. It uses a functions-directed approach to using organic and inorganic source compounds that translate into biological systems as scaffolds, micelles, dendrimers, and other delivery systems. Nanoengineering of Biomaterials offers readers up-to-date chemistry and material science insights that are readily transferrable to biomedical systems. The book also includes: Thorough introductions to alginate nanoparticle delivery of therapeutics and chitosan-based nanomaterials in biological applications Comprehensive explorations of nanostructured carrageenan as a drug carrier, gellan gum nanoparticles in drug delivery, and guar-gum nanoparticles in the delivery of bioactive molecules Practical discussions of protein-based nanoparticles for drug delivery, solid lipid nanoparticles as drug carriers, and pH-responsive nanoparticles in therapy In-depth examinations of stimuli-responsive nano carriers in drug targeting Perfect for pharmaceutical chemists, materials scientists, polymer chemists, life scientists, and medicinal chemists, Nanoengineering of Biomaterials: Drug Delivery and Biomedical Applications is also an indispensable resource for biologists and bioengineers seeking a one-stop reference on the transferability of materials chemistry and nanotechnology to biomedicine.