Quantitative Magnetic Resonance Imaging
Quantitative Magnetic Resonance Imaging

Author: Nicole Seiberlich

Publisher: Academic Press

Published: 2020-11-18

Total Pages: 1094

ISBN-13: 0128170581

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Quantitative Magnetic Resonance Imaging is a 'go-to' reference for methods and applications of quantitative magnetic resonance imaging, with specific sections on Relaxometry, Perfusion, and Diffusion. Each section will start with an explanation of the basic techniques for mapping the tissue property in question, including a description of the challenges that arise when using these basic approaches. For properties which can be measured in multiple ways, each of these basic methods will be described in separate chapters. Following the basics, a chapter in each section presents more advanced and recently proposed techniques for quantitative tissue property mapping, with a concluding chapter on clinical applications. The reader will learn: - The basic physics behind tissue property mapping - How to implement basic pulse sequences for the quantitative measurement of tissue properties - The strengths and limitations to the basic and more rapid methods for mapping the magnetic relaxation properties T1, T2, and T2* - The pros and cons for different approaches to mapping perfusion - The methods of Diffusion-weighted imaging and how this approach can be used to generate diffusion tensor - maps and more complex representations of diffusion - How flow, magneto-electric tissue property, fat fraction, exchange, elastography, and temperature mapping are performed - How fast imaging approaches including parallel imaging, compressed sensing, and Magnetic Resonance - Fingerprinting can be used to accelerate or improve tissue property mapping schemes - How tissue property mapping is used clinically in different organs - Structured to cater for MRI researchers and graduate students with a wide variety of backgrounds - Explains basic methods for quantitatively measuring tissue properties with MRI - including T1, T2, perfusion, diffusion, fat and iron fraction, elastography, flow, susceptibility - enabling the implementation of pulse sequences to perform measurements - Shows the limitations of the techniques and explains the challenges to the clinical adoption of these traditional methods, presenting the latest research in rapid quantitative imaging which has the possibility to tackle these challenges - Each section contains a chapter explaining the basics of novel ideas for quantitative mapping, such as compressed sensing and Magnetic Resonance Fingerprinting-based approaches

Fluorine Magnetic Resonance Imaging
Fluorine Magnetic Resonance Imaging

Author: Ulrich Flogel

Publisher: CRC Press

Published: 2016-10-26

Total Pages: 426

ISBN-13: 1315340933

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Over the past decade, fluorine (19F) magnetic resonance imaging (MRI) has garnered significant scientific interest in the biomedical research community owing to the unique properties of fluorinated materials and the 19F nucleus. Fluorine has an intrinsically sensitive nucleus for MRI. There is negligible endogenous 19F in the body and thus there is no background signal. Fluorine-containing compounds are ideal tracer labels for a wide variety of MRI applications. Moreover, the chemical shift and nuclear relaxation rate can be made responsive to physiology via creative molecular design. This book is an interdisciplinary compendium that details cutting-edge science and medical research in the emerging field of 19F MRI. Edited by Ulrich Flögel and Eric Ahrens, two prominent MRI researchers, this book will appeal to investigators involved in MRI, biomedicine, immunology, pharmacology, probe chemistry, and imaging physics.

Stimulated Raman Scattering Microscopy
Stimulated Raman Scattering Microscopy

Author: Ji-Xin Cheng

Publisher: Elsevier

Published: 2021-12-04

Total Pages: 612

ISBN-13: 0323903371

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Stimulated Raman Scattering Microscopy: Techniques and Applications describes innovations in instrumentation, data science, chemical probe development, and various applications enabled by a state-of-the-art stimulated Raman scattering (SRS) microscope. Beginning by introducing the history of SRS, this book is composed of seven parts in depth including instrumentation strategies that have pushed the physical limits of SRS microscopy, vibrational probes (which increased the SRS imaging functionality), data science methods, and recent efforts in miniaturization. This rapidly growing field needs a comprehensive resource that brings together the current knowledge on the topic, and this book does just that. Researchers who need to know the requirements for all aspects of the instrumentation as well as the requirements of different imaging applications (such as different types of biological tissue) will benefit enormously from the examples of successful demonstrations of SRS imaging in the book. Led by Editor-in-Chief Ji-Xin Cheng, a pioneer in coherent Raman scattering microscopy, the editorial team has brought together various experts on each aspect of SRS imaging from around the world to provide an authoritative guide to this increasingly important imaging technique. This book is a comprehensive reference for researchers, faculty, postdoctoral researchers, and engineers. - Includes every aspect from theoretic reviews of SRS spectroscopy to innovations in instrumentation and current applications of SRS microscopy - Provides copious visual elements that illustrate key information, such as SRS images of various biological samples and instrument diagrams and schematics - Edited by leading experts of SRS microscopy, with each chapter written by experts in their given topics

MRI
MRI

Author: Brian M. Dale

Publisher: John Wiley & Sons

Published: 2015-08-06

Total Pages: 246

ISBN-13: 1119013038

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This fifth edition of the most accessible introduction to MRI principles and applications from renowned teachers in the field provides an understandable yet comprehensive update. Accessible introductory guide from renowned teachers in the field Provides a concise yet thorough introduction for MRI focusing on fundamental physics, pulse sequences, and clinical applications without presenting advanced math Takes a practical approach, including up-to-date protocols, and supports technical concepts with thorough explanations and illustrations Highlights sections that are directly relevant to radiology board exams Presents new information on the latest scan techniques and applications including 3 Tesla whole body scanners, safety issues, and the nephrotoxic effects of gadolinium-based contrast media

Human Body Composition
Human Body Composition

Author: Steven Heymsfield

Publisher: Human Kinetics

Published: 2005

Total Pages: 544

ISBN-13: 9780736046558

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The 2nd edition of Human Body Composition includes updated information and new chapters. The editors and 35 contributors are well respected researchers in the field of body composition science. This is one of few texts that provides comprehensive coverage of body composition research. The primary intent is to present current information on research methods. This book can serve as a textbook for those who are students or new researchers. Descriptions of various methods and background information are imparted in great detail with numerous references. New chapters address energy expenditure, animal body composition, molecular genetics and body composition as it relates to disease states of cancer, HIV, obesity and certain inflammatory diseases like rheumatoid arthritis, inflammatory bowel disease, congestive heart failure and chronic obstructive pulmonary disease. This book is recommended for students and new researchers in the field of body composition research who need to learn various methods, histories and practical applications--Publisher's description.

Methodologies for Metabolomics
Methodologies for Metabolomics

Author: Norbert W. Lutz

Publisher: Cambridge University Press

Published: 2013-01-21

Total Pages: 641

ISBN-13: 0521765900

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Metabolomics, the global characterisation of the small molecule complement involved in metabolism, has evolved into a powerful suite of approaches for understanding the global physiological and pathological processes occurring in biological organisms. The diversity of metabolites, the wide range of metabolic pathways and their divergent biological contexts require a range of methodological strategies and techniques. Methodologies for Metabolomics provides a comprehensive description of the newest methodological approaches in metabolomic research. The most important technologies used to identify and quantify metabolites, including nuclear magnetic resonance and mass spectrometry, are highlighted. The integration of these techniques with classical biological methods is also addressed. Furthermore, the book presents statistical and chemometric methods for evaluation of the resultant data. The broad spectrum of topics includes a vast variety of organisms, samples and diseases, ranging from in vivo metabolomics in humans and animals to in vitro analysis of tissue samples, cultured cells and biofluids.

Magnetic Resonance Imaging of Neurological Diseases in Tropics
Magnetic Resonance Imaging of Neurological Diseases in Tropics

Author: Rakesh K Gupta

Publisher: JP Medical Ltd

Published: 2014-01-30

Total Pages: 364

ISBN-13: 9350909723

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Magnetic resonance imaging (MRI) is a scan that uses strong magnetic fields and radio waves to produce detailed images of the inside of the body. This book is a comprehensive guide to the diagnosis and management of neurological infectious diseases using MRI. Divided into four sections, the text begins with an introduction to tropical diseases of the central nervous system, and their epidemiology. The second section provides in depth coverage of the technique of MRI, from the basic principles, to clinical application and more advanced features. The following sections describe use of the technique for both infectious diseases, including tuberculosis, HIV and parasitic diseases; and noninfectious conditions, such as stroke, poisoning and epilepsy. Each chapter features numerous MRI and pathological images and extensive references. Key points Comprehensive guide to diagnosis and management of neurological infectious diseases in tropics using MRI In depth coverage of the technique, from basics to more advanced aspects Covers MRI for both infectious and noninfectious conditions Includes nearly 300 MRI and pathological images

Handbook of Magnetic Resonance Spectroscopy In Vivo
Handbook of Magnetic Resonance Spectroscopy In Vivo

Author: Paul A. Bottomley

Publisher: John Wiley & Sons

Published: 2016-10-19

Total Pages: 1231

ISBN-13: 1118997697

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This handbook covers the entire field of magnetic resonance spectroscopy (MRS), a unique method that allows the non-invasive identification, quantification and spatial mapping of metabolites in living organisms–including animal models and patients. Comprised of three parts: Methodology covers basic MRS theory, methodology for acquiring, quantifying spectra, and spatially localizing spectra, and equipment essentials, as well as vital ancillary issues such as motion suppression and physiological monitoring. Applications focuses on MRS applications, both in animal models of disease and in human studies of normal physiology and disease, including cancer, neurological disease, cardiac and muscle metabolism, and obesity. Reference includes useful appendices and look up tables of relative MRS signal-to-noise ratios, typical tissue concentrations, structures of common metabolites, and useful formulae. About eMagRes Handbooks eMagRes (formerly the Encyclopedia of Magnetic Resonance) publishes a wide range of online articles on all aspects of magnetic resonance in physics, chemistry, biology and medicine. The existence of this large number of articles, written by experts in various fields, is enabling the publication of a series of eMagRes Handbooks on specific areas of NMR and MRI. The chapters of each of these handbooks will comprise a carefully chosen selection of eMagRes articles. In consultation with the eMagRes Editorial Board, the eMagRes Handbooks are coherently planned in advance by specially-selected Editors, and new articles are written to give appropriate complete coverage. The handbooks are intended to be of value and interest to research students, postdoctoral fellows and other researchers learning about the scientific area in question and undertaking relevant experiments, whether in academia or industry. Have the content of this handbook and the complete content of eMagRes at your fingertips! Visit the eMagRes Homepage

Handbook of Neuro-Oncology Neuroimaging
Handbook of Neuro-Oncology Neuroimaging

Author: Herbert B. Newton

Publisher: Academic Press

Published: 2016-04-02

Total Pages: 866

ISBN-13: 0128011688

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Remarkable progress in neuro-oncology due to increased utilization of advanced imaging in clinical practice continues to accelerate in recent years. Refinements in magnetic resonance imaging (MRI) and computed tomography (CT) technology, and the addition of newer anatomical, functional, and metabolic imaging methods, such as MRS, fMRI, diffusion MRI, and DTI MRI have allowed brain tumor patients to be diagnosed much earlier and to be followed more carefully during treatment. With treatment approaches and the field of neuro-oncology neuroimaging changing rapidly, this second edition of the Handbook of Neuro-Oncology Neuroimaging is so relevant to those in the field, providing a single-source, comprehensive, reference handbook of the most up-to-date clinical and technical information regarding the application of neuro-Imaging techniques to brain tumor and neuro-oncology patients. This new volume will have updates on all of the material from the first edition, and in addition will feature several new important chapters covering diverse topics such as advanced imaging techniques in radiation therapy, therapeutic treatment fields, response assessment in clinical trials, surgical planning of neoplastic disease of the spine, and more. It will also serve as a resource of background information to neuroimaging researchers and basic scientists with an interest in brain tumors and neuro-oncology. - Provides a background to translational research and the use of brain imaging for brain tumors - Contains critical discussions on the potential and limitations of neuroimaging as a translational tool for the diagnosis and treatment of brain tumor and neuro-oncology patients - Presents an up-to-date reference on advanced imaging technologies, including computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography (PET), as well as the recent refinements in these techniques