Designing for Alzheimer's Disease

Designing for Alzheimer's Disease

Author: Elizabeth C. Brawley

Publisher: John Wiley & Sons

Published: 1997-04-21

Total Pages: 536

ISBN-13: 9780471139201

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Designing for Alzheimer's Disease offers a complete blueprint for effective design development and implementation, with the full benefit of Elizabeth Brawley's extensive professional background in design for aging environments and her own family's experience with Alzheimer's disease.


Design Innovations for Aging and Alzheimer's

Design Innovations for Aging and Alzheimer's

Author: Elizabeth C. Brawley

Publisher: John Wiley & Sons

Published: 2005-12-07

Total Pages: 0

ISBN-13: 9780471681182

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As our understanding of aging and Alzheimer's, and the cultural changes related to these phenomena, grows so do the implications for interior design. Focus on recent innovations in care environments for the aging with a resource dedicated to this topic. This comprehensive book features: Coverage of the emerging building types of adult day care and hospice and the increased use of gardens and outdoor space in environments for the aging. Material on sustainable design and environmentally friendly building products. Design solutions that extend beyond assisted-living facilities and nursing homes as they can be easily adapted for residential use. Photographs, line drawings, and a 16-page color insert that bring the material to life. Order your copy of this book today.


Drug Design and Discovery in Alzheimer's Disease

Drug Design and Discovery in Alzheimer's Disease

Author: Atta-ur Rahman

Publisher: Elsevier

Published: 2015-06-27

Total Pages: 785

ISBN-13: 0128039604

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Drug Design and Discovery in Alzheimer's Disease includes expert reviews of recent developments in Alzheimer's disease (AD) and neurodegenerative disease research. Originally published by Bentham as Frontiers in Drug Design and Discovery, Volume 6and now distributed by Elsevier, this compilation of the sixteen articles, written by leading global researchers, focuses on key developments in the understanding of the disease at molecular levels, identification and validation of molecular targets, as well as innovative approaches towards drug discovery, development, and delivery. Beginning with an overview of AD pharmacotherapy and existing blockbuster drugs, the reviews cover the potential of both natural and synthetic small molecules; the role of cholinesterases in the on-set and progression of AD and their inhibition; the role of beta-site APP clearing enzyme-1 (BACE-1) in the production of ß-amyloid proteins, one of the key reasons of the progression of AD; and other targets identified for AD drug discovery. - Edited and written by leading experts in Alzheimer's disease (AD) and other neurodegenerative disease drug development - Describes existing drugs for AD and current molecular understanding of the condition - Reviews recent advances in the field, including coverage of cholinesterases, BACE-1, and other drug development targets


Research Anthology on Diagnosing and Treating Neurocognitive Disorders

Research Anthology on Diagnosing and Treating Neurocognitive Disorders

Author: Management Association, Information Resources

Publisher: IGI Global

Published: 2020-08-30

Total Pages: 671

ISBN-13: 1799834425

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Cognitive impairment, through Alzheimer’s disease or other related forms of dementia, is a serious concern for afflicted individuals and their caregivers. Understanding patients’ mental states and combatting social stigmas are important considerations in caring for cognitively impaired individuals. Technology is playing an increasing role in the lives of the elderly. One of the most prevalent developments for the aging population is the use of technological innovations for intervention and treatment of individuals with mental impairments. Research Anthology on Diagnosing and Treating Neurocognitive Disorders examines the treatment, diagnosis, prevention, and therapeutic and technological interventions of neurodegenerative disorders. It also describes programs and strategies that professional and family caregivers can implement to engage and improve the quality of life of persons suffering from cognitive impairment. Highlighting a range of topics such as dementia, subjective wellbeing, and cognitive decline, this publication is an ideal reference source for speech pathologists, social workers, occupational therapists, psychologists, psychiatrists, neurologists, pediatricians, researchers, clinicians, and academicians seeking coverage on neurocognitive disorder identification and strategies for clinician support and therapies.


Global Clinical Trials for Alzheimer's Disease

Global Clinical Trials for Alzheimer's Disease

Author: Menghis Bairu

Publisher: Academic Press

Published: 2013-08-28

Total Pages: 428

ISBN-13: 0124115306

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Global Clinical Trials for Alzheimer's Disease is a handy one-stop reference for researchers and physicians planning and conducting global clinical trials in this area. This book addresses important considerations that may arise during the successful design and execution of these trials, including site selection, local regulatory issues, pharmacogenomics, ethical matters and much more. Given the saturation of traditional clinical trial markets and the worldwide progression of Alzheimer's disease, there is a need to focus on clinical trials in emerging markets and developing countries. This book provides you with a practical approach to recognizing the opportunities and tackling the challenges that are present during the planning and execution of global clinical trials for Alzheimer's disease. - Written by leading experts with hands-on experience in designing and running global Alzheimer's disease and other neurodegenerative diseases clinical trials - A step-by-step guide that provides critical information on the design, conduct and standardization necessary to effectively execute clinical trials and accelerate drug development in this area - Includes practical examples, ethical considerations, lessons learned and other valuable tools to aid the planning and implementation of Alzheimer's disease global clinical trials in emerging markets and developing countries


Advances in Visual Informatics

Advances in Visual Informatics

Author: Halimah Badioze Zaman

Publisher: Springer

Published: 2013-10-12

Total Pages: 818

ISBN-13: 3319029584

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This book constitutes the refereed proceedings of the Third International Conference on Advances in Visual Informatics, IVIC 2013, held in Selangor, Malaysia, in November 2013. The four keynotes and 69 papers presented were carefully reviewed and selected from various submissions. The papers focus on four tracks: computer visions and engineering; computer graphics and simulation; virtual and augmented reality; and visualization and social computing.


Designing Environments for People with Dementia

Designing Environments for People with Dementia

Author: Alison Bowes

Publisher: Emerald Group Publishing

Published: 2019-02-08

Total Pages: 136

ISBN-13: 1787699714

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The ebook edition of this title is Open Access and is freely available to read online. This book systematically explores and assesses the quality of the evidence base for effective and supportive design of living environments for people living with Dementia.


Alzheimer's Disease Drug Development

Alzheimer's Disease Drug Development

Author: Jeffrey Cummings

Publisher: Cambridge University Press

Published: 2022-03-31

Total Pages: 575

ISBN-13: 1108838669

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Provides a definitive overview of the complex ecosystem facilitating Alzheimer's Disease drug research and development. Demonstrates a drug's journey from in the lab, clinical trial testing, regulatory review, and marketing by pharmaceutical companies. Details the use of artificial intelligence, clinical trial management, and financing models.


Reducing the Impact of Dementia in America

Reducing the Impact of Dementia in America

Author: National Academies of Sciences Engineering and Medicine

Publisher:

Published: 2022-04-26

Total Pages:

ISBN-13: 9780309495035

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As the largest generation in U.S. history - the population born in the two decades immediately following World War II - enters the age of risk for cognitive impairment, growing numbers of people will experience dementia (including Alzheimer's disease and related dementias). By one estimate, nearly 14 million people in the United States will be living with dementia by 2060. Like other hardships, the experience of living with dementia can bring unexpected moments of intimacy, growth, and compassion, but these diseases also affect people's capacity to work and carry out other activities and alter their relationships with loved ones, friends, and coworkers. Those who live with and care for individuals experiencing these diseases face challenges that include physical and emotional stress, difficult changes and losses in their relationships with life partners, loss of income, and interrupted connections to other activities and friends. From a societal perspective, these diseases place substantial demands on communities and on the institutions and government entities that support people living with dementia and their families, including the health care system, the providers of direct care, and others. Nevertheless, research in the social and behavioral sciences points to possibilities for preventing or slowing the development of dementia and for substantially reducing its social and economic impacts. At the request of the National Institute on Aging of the U.S. Department of Health and Human Services, Reducing the Impact of Dementia in America assesses the contributions of research in the social and behavioral sciences and identifies a research agenda for the coming decade. This report offers a blueprint for the next decade of behavioral and social science research to reduce the negative impact of dementia for America's diverse population. Reducing the Impact of Dementia in America calls for research that addresses the causes and solutions for disparities in both developing dementia and receiving adequate treatment and support. It calls for research that sets goals meaningful not just for scientists but for people living with dementia and those who support them as well. By 2030, an estimated 8.5 million Americans will have Alzheimer's disease and many more will have other forms of dementia. Through identifying priorities social and behavioral science research and recommending ways in which they can be pursued in a coordinated fashion, Reducing the Impact of Dementia in America will help produce research that improves the lives of all those affected by dementia.


The End of Alzheimer's

The End of Alzheimer's

Author: Dale Bredesen

Publisher: Penguin

Published: 2017-08-22

Total Pages: 322

ISBN-13: 0735216207

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The instant New York Times and Wall Street Journal bestseller A groundbreaking plan to prevent and reverse Alzheimer’s Disease that fundamentally changes how we understand cognitive decline. Everyone knows someone who has survived cancer, but until now no one knows anyone who has survived Alzheimer's Disease. In this paradigm shifting book, Dale Bredesen, MD, offers real hope to anyone looking to prevent and even reverse Alzheimer's Disease and cognitive decline. Revealing that AD is not one condition, as it is currently treated, but three, The End of Alzheimer’s outlines 36 metabolic factors (micronutrients, hormone levels, sleep) that can trigger "downsizing" in the brain. The protocol shows us how to rebalance these factors using lifestyle modifications like taking B12, eliminating gluten, or improving oral hygiene. The results are impressive. Of the first ten patients on the protocol, nine displayed significant improvement with 3-6 months; since then the protocol has yielded similar results with hundreds more. Now, The End of Alzheimer’s brings new hope to a broad audience of patients, caregivers, physicians, and treatment centers with a fascinating look inside the science and a complete step-by-step plan that fundamentally changes how we treat and even think about AD.