The Neuropathology of Dementia

The Neuropathology of Dementia

Author: Margaret M. Esiri

Publisher: Cambridge University Press

Published: 2004-07-22

Total Pages: 600

ISBN-13: 9780521819152

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Completely rewritten and updated, this new edition is almost twice the size of its predecessor. Illustrated in colour throughout, and with contributions from the world's leading authorities, it is the definitive reference on the neuropathology of dementia. It gives practical guidance to pathologists, describes the contribution of neuroimaging to diagnosis, and surveys the clinical features of dementia. New material includes: Three entirely new chapters on neuroimaging, molecular diagnostics, and transgenic models. Two chapters on tauopathies under new authorship. A chapter under new authorship on synucleinopathies, which includes multiple system atrophy.


Dementia and Memory

Dementia and Memory

Author: Simon B. N. Thompson

Publisher: Routledge

Published: 2017-03-02

Total Pages: 234

ISBN-13: 1351945408

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Dementia and related diseases are likely to affect at least four in every hundred 75-79 year olds in the developed world over the coming years. Faced with an expanding older population, it is crucial that we develop our understanding of how to treat people suffering from such conditions. This accessible book provides extensive information on the different types of dementia and on memory problems more generally. It includes detailed coverage of how to alleviate memory problems and discussion on issues such as ageism. For the student reader, there are descriptions and discussions of key topics as well as practical step-by-step guidance. The book includes a memory test as well as a comprehensive list of useful addresses and suggestions for further reading. This book will be an invaluable resource for the trained healthcare and medical professional and for the student reader.


Handbook of Traumatic Brain Injury and Neurodegeneration

Handbook of Traumatic Brain Injury and Neurodegeneration

Author: R.J. Castellani

Publisher: IOS Press

Published: 2020-04-24

Total Pages: 506

ISBN-13: 164368065X

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Holbourne’s theory that rotational head movement and shear strains were limiting factors in producing acute parenchymal brain damage was a watershed moment in understanding traumatic brain injury (TBI). Long term effects, and in particular neurodegenerative proteinopathy subsequent to TBI, remain theoretical, notwithstanding the poorly understood ‘punch drunk’ syndrome of the early and mid-20th century, and the 21st century concept of chronic traumatic encephalopathy. This book, the Handbook of Traumatic Brain Injury and Neurodegeneration, has as its theme the marriage between neurodegenerative disease and neurotrauma through TBI surrogates such as sport, military service, and experimental models, and the legitimacy of that marriage. In the 32 contributions included here, this handbook not only explores the deleterious effects of genuine TBI, but also, and more importantly, the relationship between TBI and neurodegeneration. Controversy notwithstanding, there is much to be learned about the biological effects of TBI, substrates for long-term sequelae, the relationship between TBI and diverse neuropsychiatric disorders, and targets for therapy. The overall message to the neuroscience community from these papers may be a cautionary tale. The null hypothesis, that there is no causal relationship between TBI and progressive neurodegenerative disease, appears to be very much in play, and the book will be of interest to all those working in the field.


Chronic Traumatic Encephalopathy

Chronic Traumatic Encephalopathy

Author: Andrew E. Budson

Publisher: Elsevier Health Sciences

Published: 2017-07-14

Total Pages: 199

ISBN-13: 0323544266

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Get a thorough, expert overview of the many key facets of chronic traumatic encephalopathy (CTE) with this concise, practical resource by Drs. Andrew E. Budson, Ann C. McKee, Robert C. Cantu, and Robert A. Stern. This easy-to-read reference is based on lectures from Boston University’s Alzheimer’s Disease Center’s November 2016 two-day conference on CTE. Features a wealth of information on CTE, ideal for neurologists, neurosurgeons, psychologists and other practitioners who see patients with concussions or a history of brain trauma Helps health care providers understand how common concussions and CTE have become in adults of all ages, and how serious are the long-term consequences are if not managed properly Discusses the history, pathology, and genetics of CTE as well as the new criteria, differential diagnosis, and treatment of CTE Consolidates today’s available information and guidance in this timely area into one convenient resource Features a wealth of information on CTE, ideal for neurologists, neurosurgeons, psychologists and other practitioners who see patients with concussions or a history of brain trauma. Helps health care providers understand how common concussions and CTE have become in adults of all ages, and how serious are the long-term consequences are if not managed properly. Discusses the history, pathology, and genetics of CTE as well as the new criteria, differential diagnosis, and treatment of CTE. Consolidates today’s available information and guidance in this timely area into one convenient resource.


Chronic Traumatic Encephalopathy (CTE)

Chronic Traumatic Encephalopathy (CTE)

Author: Charles J. Golden

Publisher: Springer

Published: 2019-06-20

Total Pages: 61

ISBN-13: 3030232883

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The term chronic traumatic encephalopathy (CTE) has recently gained a significant amount of media coverage. However, a large proportion of the information disseminated through the media pertaining to the etiology, neuropathology, and clinical manifestations of CTE are not corroborated by empirical research, and are disputed by prominent researchers who study sports related head injury. This book reviews the existing literature pertaining to these components of CTE and includes unique case studies of several retired NFL players that received a comprehensive neuropsychological battery from a board certified neuropsychologist, among other populations. It investigates the claim that CTE causes depression, violent behavior, and an increased risk for suicide by providing an in depth discussion using empirical data. Highlighting the importance of adhering to post concussion protocol and appreciating the long-term consequences of repeated head trauma, this unique review of the current research on CTE will be useful to students and professionals in psychology and neurology.


League of Denial

League of Denial

Author: Mark Fainaru-Wada

Publisher: Crown

Published: 2014-08-26

Total Pages: 457

ISBN-13: 0770437567

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NEW YORK TIMES BESTSELLER • The story of how the NFL, over a period of nearly two decades, denied and sought to cover up mounting evidence of the connection between football and brain damage “League of Denial may turn out to be the most influential sports-related book of our time.”—The Boston Globe “Professional football players do not sustain frequent repetitive blows to the brain on a regular basis.” So concluded the National Football League in a December 2005 scientific paper on concussions in America’s most popular sport. That judgment, implausible even to a casual fan, also contradicted the opinion of a growing cadre of neuroscientists who worked in vain to convince the NFL that it was facing a deadly new scourge: a chronic brain disease that was driving an alarming number of players—including some of the all-time greats—to madness. In League of Denial, award-winning ESPN investigative reporters Mark Fainaru-Wada and Steve Fainaru tell the story of a public health crisis that emerged from the playing fields of our twenty-first-century pastime. Everyone knows that football is violent and dangerous. But what the players who built the NFL into a $10 billion industry didn’t know—and what the league sought to shield from them—is that no amount of padding could protect the human brain from the force generated by modern football, that the very essence of the game could be exposing these players to brain damage. In a fast-paced narrative that moves between the NFL trenches, America’s research labs, and the boardrooms where the NFL went to war against science, League of Denial examines how the league used its power and resources to attack independent scientists and elevate its own flawed research—a campaign with echoes of Big Tobacco’s fight to deny the connection between smoking and lung cancer. It chronicles the tragic fates of players like Hall of Fame Pittsburgh Steelers center Mike Webster, who was so disturbed at the time of his death he fantasized about shooting NFL executives, and former San Diego Chargers great Junior Seau, whose diseased brain became the target of an unseemly scientific battle between researchers and the NFL. Based on exclusive interviews, previously undisclosed documents, and private emails, this is the story of what the NFL knew and when it knew it—questions at the heart of a crisis that threatens football, from the highest levels all the way down to Pop Warner.


Sports Science Handbook: A-H

Sports Science Handbook: A-H

Author: Simon P. R. Jenkins

Publisher: multi-science publishing

Published: 2005

Total Pages: 426

ISBN-13: 9780906522363

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A valuable reference source for professionals and academics in this field, this is an encyclopedia-dictionary of the many scientific and technical terms now encountered in kinesiology and exercise science.


Kaplan & Sadock's Concise Textbook of Clinical Psychiatry

Kaplan & Sadock's Concise Textbook of Clinical Psychiatry

Author: Benjamin J. Sadock

Publisher: Lippincott Williams & Wilkins

Published: 2008

Total Pages: 756

ISBN-13: 9780781787468

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Ideal for any student or health care professional who needs an authoritative text that is sharply focused on clinical psychiatry, this book contains the most relevant clinical material from the bestselling "Kaplan and Sadock's Synopsis of Psychiatry, 10th Edition" and includes updated information on recently introduced psychiatric drugs.