Data Mining Techniques for the Life Sciences
Data Mining Techniques for the Life Sciences

Author: Oliviero Carugo

Publisher: Humana

Published: 2016-08-23

Total Pages: 407

ISBN-13: 9781493956883

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Most life science researchers will agree that biology is not a truly theoretical branch of science. The hype around computational biology and bioinformatics beginning in the nineties of the 20th century was to be short lived (1, 2). When almost no value of practical importance such as the optimal dose of a drug or the three-dimensional structure of an orphan protein can be computed from fundamental principles, it is still more straightforward to determine them experimentally. Thus, experiments and observationsdogeneratetheoverwhelmingpartofinsightsintobiologyandmedicine. The extrapolation depth and the prediction power of the theoretical argument in life sciences still have a long way to go. Yet, two trends have qualitatively changed the way how biological research is done today. The number of researchers has dramatically grown and they, armed with the same protocols, have produced lots of similarly structured data. Finally, high-throu- put technologies such as DNA sequencing or array-based expression profiling have been around for just a decade. Nevertheless, with their high level of uniform data generation, they reach the threshold of totally describing a living organism at the biomolecular level for the first time in human history. Whereas getting exact data about living systems and the sophistication of experimental procedures have primarily absorbed the minds of researchers previously, the weight increasingly shifts to the problem of interpreting accumulated data in terms of biological function and bio- lecular mechanisms.

Life Science Data Mining
Life Science Data Mining

Author: Stephen T. C. Wong

Publisher: World Scientific Publishing Company

Published: 2006

Total Pages: 392

ISBN-13:

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This timely book identifies and highlights the latest data mining paradigms to analyze, combine, integrate, model and simulate vast amounts of heterogeneous multi-modal, multi-scale data for emerging real-world applications in life science.The cutting-edge topics presented include bio-surveillance, disease outbreak detection, high throughput bioimaging, drug screening, predictive toxicology, biosensors, and the integration of macro-scale bio-surveillance and environmental data with micro-scale biological data for personalized medicine. This collection of works from leading researchers in the field offers readers an exceptional start in these areas.

Introduction to Data Mining for the Life Sciences
Introduction to Data Mining for the Life Sciences

Author: Rob Sullivan

Publisher: Springer Science & Business Media

Published: 2012-01-07

Total Pages: 644

ISBN-13: 1597452904

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Data mining provides a set of new techniques to integrate, synthesize, and analyze tdata, uncovering the hidden patterns that exist within. Traditionally, techniques such as kernel learning methods, pattern recognition, and data mining, have been the domain of researchers in areas such as artificial intelligence, but leveraging these tools, techniques, and concepts against your data asset to identify problems early, understand interactions that exist and highlight previously unrealized relationships through the combination of these different disciplines can provide significant value for the investigator and her organization.

Data Mining: Concepts and Techniques
Data Mining: Concepts and Techniques

Author: Jiawei Han

Publisher: Elsevier

Published: 2011-06-09

Total Pages: 740

ISBN-13: 0123814804

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Data Mining: Concepts and Techniques provides the concepts and techniques in processing gathered data or information, which will be used in various applications. Specifically, it explains data mining and the tools used in discovering knowledge from the collected data. This book is referred as the knowledge discovery from data (KDD). It focuses on the feasibility, usefulness, effectiveness, and scalability of techniques of large data sets. After describing data mining, this edition explains the methods of knowing, preprocessing, processing, and warehousing data. It then presents information about data warehouses, online analytical processing (OLAP), and data cube technology. Then, the methods involved in mining frequent patterns, associations, and correlations for large data sets are described. The book details the methods for data classification and introduces the concepts and methods for data clustering. The remaining chapters discuss the outlier detection and the trends, applications, and research frontiers in data mining. This book is intended for Computer Science students, application developers, business professionals, and researchers who seek information on data mining. - Presents dozens of algorithms and implementation examples, all in pseudo-code and suitable for use in real-world, large-scale data mining projects - Addresses advanced topics such as mining object-relational databases, spatial databases, multimedia databases, time-series databases, text databases, the World Wide Web, and applications in several fields - Provides a comprehensive, practical look at the concepts and techniques you need to get the most out of your data

Data Mining
Data Mining

Author: Ian H. Witten

Publisher: Elsevier

Published: 2005-07-13

Total Pages: 558

ISBN-13: 008047702X

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Data Mining, Second Edition, describes data mining techniques and shows how they work. The book is a major revision of the first edition that appeared in 1999. While the basic core remains the same, it has been updated to reflect the changes that have taken place over five years, and now has nearly double the references. The highlights of this new edition include thirty new technique sections; an enhanced Weka machine learning workbench, which now features an interactive interface; comprehensive information on neural networks; a new section on Bayesian networks; and much more. This text is designed for information systems practitioners, programmers, consultants, developers, information technology managers, specification writers as well as professors and students of graduate-level data mining and machine learning courses. - Algorithmic methods at the heart of successful data mining—including tried and true techniques as well as leading edge methods - Performance improvement techniques that work by transforming the input or output

Fundamentals of Data Mining in Genomics and Proteomics
Fundamentals of Data Mining in Genomics and Proteomics

Author: Werner Dubitzky

Publisher: Springer Science & Business Media

Published: 2007-04-13

Total Pages: 300

ISBN-13: 0387475095

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This book presents state-of-the-art analytical methods from statistics and data mining for the analysis of high-throughput data from genomics and proteomics. It adopts an approach focusing on concepts and applications and presents key analytical techniques for the analysis of genomics and proteomics data by detailing their underlying principles, merits and limitations.

Biological Data Mining And Its Applications In Healthcare
Biological Data Mining And Its Applications In Healthcare

Author: Xiaoli Li

Publisher: World Scientific

Published: 2013-11-28

Total Pages: 437

ISBN-13: 9814551023

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Biologists are stepping up their efforts in understanding the biological processes that underlie disease pathways in the clinical contexts. This has resulted in a flood of biological and clinical data from genomic and protein sequences, DNA microarrays, protein interactions, biomedical images, to disease pathways and electronic health records. To exploit these data for discovering new knowledge that can be translated into clinical applications, there are fundamental data analysis difficulties that have to be overcome. Practical issues such as handling noisy and incomplete data, processing compute-intensive tasks, and integrating various data sources, are new challenges faced by biologists in the post-genome era. This book will cover the fundamentals of state-of-the-art data mining techniques which have been designed to handle such challenging data analysis problems, and demonstrate with real applications how biologists and clinical scientists can employ data mining to enable them to make meaningful observations and discoveries from a wide array of heterogeneous data from molecular biology to pharmaceutical and clinical domains.

Data Mining in Bioinformatics
Data Mining in Bioinformatics

Author: Jason T. L. Wang

Publisher: Springer Science & Business Media

Published: 2005

Total Pages: 356

ISBN-13: 9781852336714

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Written especially for computer scientists, all necessary biology is explained. Presents new techniques on gene expression data mining, gene mapping for disease detection, and phylogenetic knowledge discovery.

Data Mining Techniques
Data Mining Techniques

Author: Michael J. A. Berry

Publisher: John Wiley & Sons

Published: 2004-04-09

Total Pages: 671

ISBN-13: 0471470643

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Many companies have invested in building large databases and data warehouses capable of storing vast amounts of information. This book offers business, sales and marketing managers a practical guide to accessing such information.

Data Mining Techniques for the Life Sciences
Data Mining Techniques for the Life Sciences

Author: Oliviero Carugo

Publisher: Humana Press

Published: 2011-03-04

Total Pages: 408

ISBN-13: 9781607614869

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Most life science researchers will agree that biology is not a truly theoretical branch of science. The hype around computational biology and bioinformatics beginning in the nineties of the 20th century was to be short lived (1, 2). When almost no value of practical importance such as the optimal dose of a drug or the three-dimensional structure of an orphan protein can be computed from fundamental principles, it is still more straightforward to determine them experimentally. Thus, experiments and observationsdogeneratetheoverwhelmingpartofinsightsintobiologyandmedicine. The extrapolation depth and the prediction power of the theoretical argument in life sciences still have a long way to go. Yet, two trends have qualitatively changed the way how biological research is done today. The number of researchers has dramatically grown and they, armed with the same protocols, have produced lots of similarly structured data. Finally, high-throu- put technologies such as DNA sequencing or array-based expression profiling have been around for just a decade. Nevertheless, with their high level of uniform data generation, they reach the threshold of totally describing a living organism at the biomolecular level for the first time in human history. Whereas getting exact data about living systems and the sophistication of experimental procedures have primarily absorbed the minds of researchers previously, the weight increasingly shifts to the problem of interpreting accumulated data in terms of biological function and bio- lecular mechanisms.