Cyclodextrins are an extremely versatile class of chemicals highly prized for their ability to incorporate a plethora of organic, inorganic and biologic guest molecules into their hydrophobic cavities and form host-guest inclusion complexes. As excellent molecular receptors, they have long been exploited in many important industries such as food and agriculture, pharmaceuticals, cosmetics, textiles, analytical chemistry and enzyme mimics.Researchers, technicians and application specialists in many industries will appreciate this handy volume that systematically discusses how cyclodextrins are applied in their industries. Special attention is devoted to the preparation of inclusion complexes, novel properties of the resultant complexes, and details on applying those properties to industry.
Nearly three thousand papers and patents are dedicated to the actual or potential uses of cyclodextrins in pharmacy and pharmaceutical formulations. This is the first book written for pharmacists and pharmaceutical technologists which not only critically summarizes the enormous amount of literature available, but which can be used as a handbook when looking for solutions to practical problems. The fundamentals -- chemistry of cyclodextrins and their derivatives -- their physical and chemical properties are condensed to the most relevant items in Chapters 1 and 2. Chapter 3 deals with the adsorption, metabolism and toxicological properties of cyclodextrins. Chapter 4 explains the formulation, structure, composition and advantageous effects of the cyclodextrin inclusion complexes. Chapter 5 describes the methods for preparation and characterization of drug/cyclodextrin complexes. Chapters 6 and 7 are dedicated to the pharmacokinetics, biopharmaceutical and technological aspects of drug/CD complexes. Chapter 8 treats the application and effects of cyclodextrins in various drug formulations. The Appendix comprises a collection of recipes for any type of drug formulation. This book is aimed at those who use cyclodextrins in drug formulations, to improve the properties of existing drug formulations, or who want to prepare quite new formulations.
Chemistry was at one time completely described in terms of collision theo ry, in which one molecule collided with another, sometimes producing reac tion. Then came the realization that enzymes which are highly efficient ca talysts, work by way of prior complexation, often stereospecific, which is then followed by chemical reaction. Thus, systems that exhibit "host-guest" relationships, i.e., that show complexing are being looked at an ever in creasing frequency. The cyclodextrins are the first and probably the most important example of compounds that exhibits complex formation. This is a book about the cyclodextrins. There are of course other compounds that exhibit "host-guest" relationships and thus bind other organic molecules, but so far they have not achieved the importance of the cyclodextrins. By their name it is obvious that cyclodextrins are cyclic compounds. The complexes that they form are therefore cyclic inclusion complexes. Because the complexes are cyclic in nature, complexation can be very strong, as op posed to 1t-complex, electrostatic, or apolar complexes in which complex formation is two-dimensional rather than three-dimensional. Cyclodextrins turn out to be excellent models of enzymes. This is proba bly not fortuitous because they were first sought since it was discovered that the principal binding in the enzyme chymotrypsin was a cyclic inclusion complex. Cyclodextrins can do more than form cyclic inclusion complexes, they can catalyze as well. But catalysis always occurs after complex formation.
Cyclodextrin Chemistry covers the preparation of cyclodextrins and cyclodextrin derivatives (CDs), and their applications in industrial and non-industrial areas. An overall theme in the book is the screening of cyclodextrin glycosyltransferase (CGTase), the preparation of sugar-branched cyclodextrins and CDs, and the use of CDs for reconstructing various supermolecule systems. The specific content also includes preparation methods, spectroscopy techniques for CDs analysis, and potential applications in food packaging, nutrient fortification, medicine, cosmetics, textiles, chemicals, feed, agriculture, and environment.It summarizes the research merit of CDs in the past twenty years and also emphasizes hot topics and important areas of cyclodextrin chemistry in the future.
The comprehensive resource for understanding the structure, properties, and applications of cyclodextrins Cyclodextrins: Properties and Industrial Applications is a comprehensive resource that includes information on cyclodextrins (CDs) structure, their properties, formation of inclusion complex with various compounds as well as their applications. The authors Sahar Amiri and Sanam Amiri, noted experts in the field of cyclodextrins, cover both the basic and applied science in chemistry, biology, and physics of CDs and offers scientists and engineers an understand of cyclodextrins. Cyclodextrins are a family of cyclic oligosaccharides consisting of (α-1,4)-linked α-D-glucopyranose units. The formation of inclusion complex between CDs as host and guest molecules is based on non-covalent interaction such as hydrogen bonding or van der waals interactions and lead to the formation of supramolecular structures. These supramolecular structures can be used as macroinitiator for initiating various type of reactions. CDs are widely used in many industrial products such as pharmacy, food and flavours, chemistry, chromatography, catalysis, biotechnology, agriculture, cosmetics, hygiene, medicine, textiles, drug delivery, packing, separation processes, environment protection, fermentation, and catalysis. This important resource: Offers a basic understanding of cyclodextrins for researchers and engineers Includes information of the basic structure of cyclodextrins and their properties Reviews how cyclodextrins can be applied in a variety of fields including medicine, chemistry, textiles, packing, and many others Shows how encapsulate corrosion inhibitors became active in corrosive electrolytes to ensure delivery of the inhibitors to corrosion sites and long-term corrosion protection Cyclodextrins offers research scientists and engineers a wealth of information about CDs with particular focus on how cyclodextrins are applied in various ways including in drug delivery, the food industry, and many other areas.
This authoritative reference work presents comprehensive information about one of the most important and most wide-spread classes of (bio)organic compounds: the polysaccharides. The comprehensive and thoroughly up-to-date handbook presents the sources, identification, analysis, biosynthesis, biotechnology and applications of important polysaccharides likes starches, cellulose, chitin, gum and microbial polysaccharides. Polysaccharides can exhibit complex structure and various functional activities. These bio macromolecules can therefore serve as raw materials for various different materials, e.g. rayon, cellulose acetate, celluloid and nitrocellulose; and they find multiple applications, for instance as surgical threads (chitin), as sources of energy, dietary fibers, as blood flow adjuvants, in cosmetics, emulsion stabilizers, film formers, binders, viscosity increasing agents or skin conditioning agenta, as food additives in gums, chewing gum bases and as vaccines. Polysaccharides form the basis for useful products, like xanthan gum, dextran, welan gum, gellan gum, diutan gum and pullulan. Some of the polysaccharide-derived products have interesting and useful properties and show biological activities, such as immunomodulatory, antibacterial, anti-mutagenic, radioprotective, anti-oxidative, anti-ulcer, antidepressant, anti-septicaemic or anti-inflammatory activities. All these applications and properties of polysaccharides are for the first time compiled in a thorough and comprehensive overview in the present work. This reference work is organized thematically in four parts: Part I. Polysaccharides: Occurrence, Structure, Distribution and Biotechnology. Part II. Methods. Part III. Bioactive Polysaccharides. Part IV. Polysaccharides as Food. This reference work is edited by experienced experts, all chapters are written by well recognized international specialists. It is useful to all those working in the field of botany, phytochemistry, pharmacy, drug delivery, molecular biology, metabolomics, forestry, environment, conservation, biotechnology and NGOs working for forest protection.
This book presents the historical development of Cyclodextrins by scientists who have made outstanding contribution to the field. Cyclodextrins are safe, cage-like molecules that have found major applications in many industrial sectors such as medicine, food, agriculture, environment and chemistry.
Nanoencapsulation Technologies for the Food and Nutraceutical Industries is a compendium which collects, in an easy and compact way, state-of-the-art details on techniques for nanoencapsulation of bioactive compounds in food and nutraceutical industries. The book addresses important modern technologies, including biopolymer based nano-particle formation techniques, formulation based processes, such as nano-liposomes and nano-emulsions, process based nano-encapsulation, such as electro-spinning and nano-spray drying, natural nano-carrier based processes, like casein and starch nano-particles, and other recent advances. This definitive reference manual is ideal for researchers and industry personnel who want to learn more about basic concepts and recent developments in nanotechnology research. - Serves as a compendium of recent techniques and systems for nanoencapsulation of bioactive compounds - Brings together basic concepts and the potential of nanoencapsulation technologies, also including their novel applications in functional foods and nutraceutical systems - Includes biopolymer based nano-particle formation techniques, formulation based processes, process based nanoencapsulation, and nano-carrier based process
Years of human ignorance has diminished our natural resources and aged our planet. Now, people are making an effort to change the way they are treating the planet. Being more environmentally conscious about the impact materials used for fashion have on our planet is one-way designers can reduce waste and help enable a better world. By going eco-friendly can be less harmful to our natural resources. Not all fashion is following this eco-friendly trend, but more designers are embracing the trend toward eco-fashion than ever before. If the entire fashion industry became eco-friendly, it would make a huge difference for future generations because the fashion industry employs over a billion people globally. There is need for eco-friendly wet processing that is sustainable and beneficial methods. Number of sustainable practices has been implemented by various textile processing industries such as Eco- friendly bleaching; Peroxide bleaching; Eco-friendly dyeing and Printing; Low impact dyes; Natural dyes; Azo Free dyes; Phthalates Free Printing. There are a variety of materials considered "environmentally-friendly" for a variety of reasons. The industry is desperately in the need of newer and very efficient dyeing/finishing and functional treatments of textiles. There is growing awareness and readiness to adapt new perspective on industrial upgradation of Cleaner Production Programme, such new technologies help enterprises achieve green production and cost reduction at the same time. Green Production has become necessary for enterprises under the upgrade and transformation policy. The book Eco-Friendly Textile Dyeing and Finishing covers topics in the area of sustainable practices in textile dyeing and finishing.
Offers practical examples of bioreactor systems that use immobilized biocatalysts - including enzymes and microbial cells - that have been implemented on the industrial level in Japan and Denmark. The book provides information on the current status of successful new bioreactor technologies.
