New Advances on Zika Virus Research

New Advances on Zika Virus Research

Author: Luis Martinez-Sobrido

Publisher: MDPI

Published: 2019-04-02

Total Pages: 554

ISBN-13: 3038977640

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Zika virus (ZIKV) is a mosquito-borne member of the Flaviviridae family that historically has been associated with mild febrile illness. However, the recent outbreaks in Brazil in 2015 and its rapid spread throughout South and Central America and the Caribbean, together with its association with severe neurological disorders—including fetal microcephaly and Guillain-Barré syndrome in adults—have changed the historic perspective of ZIKV. Currently, ZIKV is considered an important public health concern that has the potential to affect millions of people worldwide. The significance of ZIKV in human health and the lack of approved vaccines and/or antiviral drugs to combat ZIKV infection have triggered a global effort to develop effective countermeasures to prevent and/or treat ZIKV infection. In this Special Issue of Viruses, we have assembled a collection of 32 research and review articles that cover the more recent advances on ZIKV molecular biology, replication and transmission, virus–host interactions, pathogenesis, epidemiology, vaccine development, antivirals, and viral diagnosis.


Current Topics in Zika

Current Topics in Zika

Author: Alfonso J. Rodriguez-Morales

Publisher: BoD – Books on Demand

Published: 2018-06-13

Total Pages: 100

ISBN-13: 1789232708

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Zika was an arbovirus not considered relevant until the epidemics of 2007, where in the islands of the Pacific, Yap, Micronesia, and others, and later in the Americas in 2015-2016, it created a significant public health threat. Zika is a flavivirus that has been especially important not just for the high number of cases but also for its related morbidity. In the case of adult population, multiple neurological diseases are already associated and in pregnant women because of its confirmed teratogenic capacity, leading to microcephaly as well as other central nervous system (CNS) birth defects. This book tried to update the significant epidemiological and clinical research in many aspects with a multinational perspective.


Zika: The Emerging Epidemic

Zika: The Emerging Epidemic

Author: Donald G. McNeil Jr.

Publisher: W. W. Norton & Company

Published: 2016-06-28

Total Pages: 165

ISBN-13: 0393609170

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A gripping narrative about the origins and spread of the Zika virus by New York Times science reporter Donald G. McNeil Jr. Until recently, Zika—once considered a mild disease—was hardly a cause for global panic. But as early as August 2015, doctors in northeast Brazil began to notice a trend: many mothers who had recently experienced symptoms of the Zika virus were giving birth to babies with microcephaly, a serious disorder characterized by unusually small heads and brain damage. By early 2016, Zika was making headlines as evidence mounted—and eventually confirmed—that microcephaly is caused by the virus, which can be contracted through mosquito bites or sexually transmitted. The first death on American soil, in February 2016, was confirmed in Puerto Rico in April. The first case of microcephaly in Puerto Rico was confirmed on May 13, 2016. The virus has been known to be transmitted by the Aedes aegypti or Yellow Fever mosquito, but now Aedes albopictus, the Asian Tiger mosquito, has been found to carry it as well, which means it might affect regions as far north as New England and the Great Lakes. Right now, at least 298 million people in the Americas live in areas “conducive to Zika transmission,” according to a recent study. Over the next year, more than 5 million babies will be born. In Zika: The Emerging Epidemic, Donald G. McNeil Jr. sets the facts straight in a fascinating exploration of Zika’s origins, how it’s spreading, the race for a cure, and what we can do to protect ourselves now.


Japanese Encephalitis and West Nile Viruses

Japanese Encephalitis and West Nile Viruses

Author: John Mackenzie

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 423

ISBN-13: 3642594034

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Japanese encephalitis and West Nile viruses are members of the Japanese encephalitis serological group of the genus Flavivirus and therefore closely related genetically and antigenically. They share a number of properties, including the use of birds as their major wildlife maintenance host and Culicine mosquitoes for transmission, and they are both associated with severe human disease, as well as fatal infections in horses. The emergence of these two viruses, and their well-established propensity to colonise new areas, make it timely to re-examine their ecology, biology, molecular structure, replication and epidemiology, and these therefore provide the focus of this volume.


Current Topics in Public Health

Current Topics in Public Health

Author: Alfonso J. Rodriguez-Morales

Publisher: IntechOpen

Published: 2013-05-15

Total Pages: 744

ISBN-13: 9789535111214

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Public Health is regarded as the basis and cornerstone of health, generally and in medicine. Defined as the science and art of preventing disease, prolonging life and promoting health through the organized efforts and informed choices of society, organizations, public and private, communities and individuals, this discipline has been renewed by the incorporation of multiple actors, professions, knowledge areas and it has also been impacted and promoted by multiple technologies, particularly - the information technology. As a changing field of knowledge, Public Health requires evidence-based information and regular updates. Current Topics in Public Health presents updated information on multiple topics related to actual areas of interest in this growing and exciting medical science, with the conception and philosophy that we are working to improve the health of the population, rather than treating diseases of individual patients, taking decisions about collective health care that are based on the best available, current, valid and relevant evidence, and finally within the context of available resources. With participation of authors from multiple countries, many from developed and developing ones, this book offers a wide geographical perspective. Finally, all these characteristics make this book an excellent update on many subjects of world public health.


Pandemic Outbreaks in the 21st Century

Pandemic Outbreaks in the 21st Century

Author: Viswanath Buddolla

Publisher: Elsevier

Published: 2021-08-24

Total Pages: 328

ISBN-13: 0323900011

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In the past two decades, several pandemics have ravaged the globe, giving us several lessons on infectious disease epidemiology, the importance of initial detection and characterization of outbreak viruses, the importance of viral epidemic prevention steps, and the importance of modern vaccines. Pandemic Outbreaks in the Twenty-First Century: Epidemiology, Pathogenesis, Prevention, and Treatment summarizes the improvements in the 21st century to overcome / prevent / treat global pandemic with future prospective. Divided into 9 chapters, the book begins with an in-depth introduction to the lessons learned from the first pandemic of the 21st century. It describes the history, present and future in terms of detection, prevention and treatment. Followed by chapters on the outbreak, treatment strategies and clinical management of several infectious diseases like MERS, SARD and COVID 19, Pandemic Outbreaks in the Twenty-First Century: Epidemiology, Pathogenesis, Prevention, and Treatment, presents chapters on immunotherapies and vaccine technologies to combat pandemic outbreak and challenges. The book finishes with a chapter on the current knowledge and technology to control pandemic outbreaks. All are presented in a practical short format, making this volume a valuable resource for very broad academic audience. Provides insight to the lessons learned from past pandemics Gives recommendations, future direction in terms of detection, prevention and treatment of pandemics Guides readers through the status and recent developments of vaccines to overcome or prevent pandemics Shows how to enhance the host innate immunity in infectious diseases Includes a chapter on immunotherapies to combat pandemic outbreaks


Current Concepts in Zika Research

Current Concepts in Zika Research

Author: Alfonso J. Rodriguez-Morales

Publisher: BoD – Books on Demand

Published: 2021-02-10

Total Pages: 131

ISBN-13: 1838808752

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Zika is an arboviral disease that has caused a significant impact, especially in the Americas after the epidemics in 2015 and 2016. The World Health Organization (WHO) declared it as a Public Health Emergency of International Concern (PHEIC) in 2016, linking it with the Guillain-Barré syndrome and especially the microcephaly and the Congenital Zika Syndrome. The multiple consequences, especially in the central and peripheral nervous system in the short and long term, are still to be better defined. Therefore research on Zika is crucial. This book presents an update of the significant epidemiological and clinical research of Zika over the last years in many aspects and from a multinational perspective.


CDC Yellow Book 2018: Health Information for International Travel

CDC Yellow Book 2018: Health Information for International Travel

Author: Centers for Disease Control and Prevention CDC

Publisher: Oxford University Press

Published: 2017-04-17

Total Pages: 705

ISBN-13: 0190628634

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THE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018 As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel has never been greater. For both international travelers and the health professionals who care for them, the CDC Yellow Book 2018: Health Information for International Travel is the definitive guide to staying safe and healthy anywhere in the world. The fully revised and updated 2018 edition codifies the U.S. government's most current health guidelines and information for international travelers, including pretravel vaccine recommendations, destination-specific health advice, and easy-to-reference maps, tables, and charts. The 2018 Yellow Book also addresses the needs of specific types of travelers, with dedicated sections on: · Precautions for pregnant travelers, immunocompromised travelers, and travelers with disabilities · Special considerations for newly arrived adoptees, immigrants, and refugees · Practical tips for last-minute or resource-limited travelers · Advice for air crews, humanitarian workers, missionaries, and others who provide care and support overseas Authored by a team of the world's most esteemed travel medicine experts, the Yellow Book is an essential resource for travelers -- and the clinicians overseeing their care -- at home and abroad.


Improving Health Care in Low- and Middle-Income Countries

Improving Health Care in Low- and Middle-Income Countries

Author: Lani Rice Marquez

Publisher: Springer Nature

Published: 2020-05-26

Total Pages: 254

ISBN-13: 3030431126

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This open access book is a collection of 12 case studies capturing decades of experience improving health care and outcomes in low- and middle-income countries. Each case study is written by healthcare managers and providers who have implemented health improvement projects using quality improvement methodology, with analysis from global health experts on the practical application of improvement methods. The book shows how frontline providers in health and social services can identify gaps in care, propose changes to address those gaps, and test the effectiveness of their changes in order to improve health processes and outcomes. The chapters feature cases that provide real-life examples of the challenges, solutions, and benefits of improving healthcare quality and clearly demonstrate for readers what quality improvement looks like in practice:Addressing Behavior Change in Maternal, Neonatal, and Child Health with Quality Improvement and Collaborative Learning Methods in GuatemalaHaiti’s National HIV Quality Management Program and the Implementation of an Electronic Medical Record to Drive Improvement in Patient CareScaling Up a Quality Improvement Initiative: Lessons from Chamba District, IndiaPromoting Rational Use of Antibiotics in the Kyrgyz RepublicStrengthening Services for Most Vulnerable Children through Quality Improvement Approaches in a Community Setting: The Case of Bagamoyo District, TanzaniaImproving HIV Counselling and Testing in Tuberculosis Service Delivery in Ukraine: Profile of a Pilot Quality Improvement Team and Its Scale‐Up JourneyImproving Health Care in Low- and Middle-Income Countries: A Case Book will find an engaged audience among healthcare providers and administrators implementing and managing improvement projects at Ministries of Health in low- to middle-income countries. The book also aims to be a useful reference for government donor agencies, their implementing partners, and other high-level decision makers, and can be used as a course text in schools of public health, public policy, medicine, and development. ACKNOWLEDGMENT:This work was conducted under the USAID Applying Science to Strengthen and Improve Systems (ASSIST) Project, USAID Award No. AID-OAA-A-12-00101, which is made possible by the generous support of the American people through the U.S. Agency for International Development (USAID). DISCLAIMER:The contents of this book are the sole responsibility of the Editor(s) and do not necessarily reflect the views of USAID or the United States Government. div=""^


Zika Virus and Diseases

Zika Virus and Diseases

Author: Suzane R. da Silva

Publisher: John Wiley & Sons

Published: 2018-02-14

Total Pages: 278

ISBN-13: 1119408652

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Compiles the most current information on the Zika virus and its associated diseases This comprehensive book provides the most up-to-date information for students, medical students, and scientists on Zika virus and its associated diseases. It includes all the information related to the Zika virus since its discovery in 1947; its epidemic outbreak in 2007-2014; how the epidemiology changed in America in 2015-2016; its mode of transmission; how to prevent and treat it; and associated diseases. Zika Virus and Diseases: From Molecular Biology to Epidemiology offers complete and up-to-date coverage in 10 chapters. It presents information from papers that attempted to associate the virus with diseases in Africa until the first animal experiment; discusses its association with Guillain-Barré syndrome and microcephaly; describes the basic mechanisms for Zika (ZIKV) replication, including important differences between Dengue (DENV), West-Nile virus (WNV), and ZIKV; explains the difference between the strains and discusses the pathogenesis of them; covers the papers that showed all the interferences that Zika can cause, and the pathways which can be modified; and more. The first book since 1947 to put together all the scientific information Compiles all the information received in the last year about Zika virus Clearly demonstrates the origin and discovery of the virus Zika Virus and Diseases: From Molecular Biology to Epidemiology will appeal to graduate students, medical students, basic researchers, clinicians in infectious disease, microbiology, and virology, as well as people in related disciplines interested in learning more about this topic.