Cryptorchidism

Cryptorchidism

Author: F. Hadziselimovic

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 145

ISBN-13: 3642860206

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Ferment, a sign of progress in any scientific field, has previously been lacking in the area of cryptorchidism, where the only activity has been in improving operative methods. Now, however, profound changes in the care of boys with cryptorchidism are being brought about; ideas are arising from a fresh look at comparative anatomy, and histological and experimental observa tions are being supplemented by clinical tests made possible by new hormonal agents. The treatment of cryptorchidism begins with its recognition by the pediatri cian, who until now has shown little interest because of disappointing results from chorionic gonadotropin administration. As for the surgeon, his bent toward restoration of normal anatomical relationships has kept his attention focused on the development of better surgical technics to bring the recalci trant testis into the scrotum. Both specialists have avoided the primordial question of why the testis did not descend properly. If this were known they would treat the cause of cryptorchidism, and not be satisfied merely with trying to correct its end result. As one reads this book, one sees that in most patients cryptorchidism is not caused by some anatomical structure blocking the way or by some deformity of the testis interfering with the transport mechanism. Rather, deficiencies in the hormonal environment of the fetus retard the developmen tal sequences essential to the normal differentiation and descent of the testis. The clinical solution is thus to provide the deficient substances.


Reproductive Technologies in Farm Animals

Reproductive Technologies in Farm Animals

Author: Ian Gordon

Publisher: CABI

Published: 2004

Total Pages: 356

ISBN-13: 9780851990491

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In the past half century great progress has been made in the reproductive management of farm animals, both mammals and birds. This book aims to review developments and indicate which reproductive technologies can be used commercially or in research. It begins by discussing artificial insemination and how this has recently been refined in semen sexing technology. Embryo transfer, in vitro embryo production technology and the control of oestrus and ovulation are then reviewed. Subsequent chapters consider the control of postpartum ovarian activity, seasonal breeding, multiple births and litter size, pregnancy testing, parturition, and the onset of puberty. The author then describes more recent developments in cloning and the production of transgenic animals, before a final chapter on suppressing reproductive activity.


The Cryptorchid Testis

The Cryptorchid Testis

Author: Thomas O. Abney

Publisher: CRC Press

Published: 2020-08-11

Total Pages: 183

ISBN-13: 100010303X

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Current knowledge concerning both morphological and functional cryptorchid-related alterations in the various testicular compartments is summarized in this valuable new publication. Damage to the germinal epithelium and resulting infertility in both humans and experimental animals as well as the degree of damage to the different stages of germ cell development is discussed. In addition, information concerning hormonal therapy and orchidopexy to reverse cryptorchid-related damage is provided. Morphological alterations in Sertoli and Leydig cells is discussed in terms of cellular hypertrophy and hyperplasia, alterations in organelle number and characteristics as well as changes in cell-cell junctional complexes. Changes in Sertoli cell and Leydig cell function, including gonadotropin binding, steroidogenesis and other metabolic alterations is also outlined,as well as the influence of altered testicular function on subsequent hypothalamic-pituitary changes. Vascular disruption, the potential role of paracrine substances and direct thermal damage, all of which may be responsible for the resulting detrimental changes in one or more testicular compartments, are considered.