Design and Analysis of Cross-Over Trials, Third Edition
Design and Analysis of Cross-Over Trials, Third Edition

Author: Byron Jones

Publisher: CRC Press

Published: 2014-10-08

Total Pages: 440

ISBN-13: 1439861420

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Design and Analysis of Cross-Over Trials is concerned with a specific kind of comparative trial known as the cross-over trial, in which subjects receive different sequences of treatments. Such trials are widely used in clinical and medical research, and in other diverse areas such as veterinary science, psychology, sports science, and agriculture. The first edition of this book was the first to be wholly devoted to the subject. The second edition was revised to mirror growth and development in areas where the design remained in widespread use and new areas where it had grown in importance. This new Third Edition: Contains seven new chapters written in the form of short case studies that address re-estimating sample size when testing for average bioequivalence, fitting a nonlinear dose response function, estimating a dose to take forward from phase two to phase three, establishing proof of concept, and recalculating the sample size using conditional power Employs the R package Crossover, specially created to accompany the book and provide a graphical user interface for locating designs in a large catalog and for searching for new designs Includes updates regarding the use of period baselines and the analysis of data from very small trials Reflects the availability of new procedures in SAS, particularly proc glimmix Presents the SAS procedure proc mcmc as an alternative to WinBUGS for Bayesian analysis Complete with real data and downloadable SAS code, Design and Analysis of Cross-Over Trials, Third Edition provides a practical understanding of the latest methods along with the necessary tools for implementation.

Cross-over Trials in Clinical Research
Cross-over Trials in Clinical Research

Author: Stephen S. Senn

Publisher: John Wiley & Sons

Published: 2003-07-25

Total Pages: 364

ISBN-13: 0470854588

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Cross-over trials are an important class of design used in the pharmaceutical industry and medical research, and their use continues to grow. Cross-over Trials in Clinical Research, Second Edition has been fully updated to include the latest methodology used in the design and analysis of cross-over trials. It includes more background material, greater coverage of important statistical techniques, including Bayesian methods, and discussion of analysis using a number of statistical software packages. * Comprehensive coverage of the design and analysis of cross-over trials. * Each technique is carefully explained and the mathematics is kept to a minimum. * Features many real and original examples, taken from the author's vast experience. * Includes discussion of analysis using SAS, S-Plus and, GenStat, StatXact and Excel. * Written in a style suitable for statisticians and physicians alike. * Computer programs to accompany the examples in the book can be downloaded from the Web Primarily aimed at statisticians and researchers working in the pharmaceutical industry, the book will also appeal to physicians involved in clinical research and students of medical statistics.

Design and Analysis of Cross-Over Trials, Second Edition
Design and Analysis of Cross-Over Trials, Second Edition

Author: Byron Jones

Publisher: CRC Press

Published: 2003-03-12

Total Pages: 412

ISBN-13: 9780412606403

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The first edition of Design and Analysis of Cross-Over Trials quickly became the standard reference on the subject and has remained so for more than 12 years. In that time, however, the use of cross-over trials has grown rapidly, particularly in the pharmaceutical arena, and researchers have made a number of advances in both the theory and methods applicable to these trials. Completely revised and updated, the long-awaited second edition of this classic text retains its predecessor's careful balance of theory and practice while incorporating new approaches, more data sets, and a broader scope. Enhancements in the second edition include: A new chapter on bioequivalence Recently developed methods for analyzing longitudinal continuous and categorical data Real-world examples using the SAS system A comprehensive catalog of designs, datasets, and SAS programs available on a companion Web site at www.crcpress.com The authors' exposition gives a clear, unified account of the design and analysis of cross-over trials from a statistical perspective along with their methodological underpinnings. With SAS programs and a thorough treatment of design issues, Design and Analysis of Cross-Over Trials, Second Edition sets a new standard for texts in this area and undoubtedly will be of direct practical value for years to come.

Crossover Fiction
Crossover Fiction

Author: Sandra L. Beckett

Publisher: Routledge

Published: 2010-11-24

Total Pages: 360

ISBN-13: 1135861307

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In Crossover Fiction, Sandra L. Beckett explores the global trend of crossover literature and explains how it is transforming literary canons, concepts of readership, the status of authors, the publishing industry, and bookselling practices. This study will have significant relevance across disciplines, as scholars in literary studies, media and cultural studies, visual arts, education, psychology, and sociology examine the increasingly blurred borderlines between adults and young people in contemporary society, notably with regard to their consumption of popular culture.

Mormon Studies
Mormon Studies

Author: Ronald Helfrich, Jr.

Publisher: McFarland

Published: 2021-12-30

Total Pages: 240

ISBN-13: 1476645116

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Mormonism arose in early 19th century New York and has fired the imaginations of its devotees, critics, and students ever since. Some intellectuals and academics read Mormonism as the product of economic change wrought by the Erie Canal in the Burned-over District of western New York State and upper north-eastern Ohio. Others read Mormonism as an authoritarian reaction to Jacksonian democracy. Finally, some, including most of those who became Mormons in the early 19th century and most of those who are believing Mormons today, read Mormonism as the intervention of God in human history. This book engages with Mormon Studies from its beginnings in the early nineteenth century to the end of the 20th century. It covers those who fought over Mormonism's truth or falsity, on those who tried to understand Mormonism as a religious and sociological phenomenon, and on those who explored the history of Mormonism from a more dispassionate perspective. It concludes with an exploration of the culture war that erupted as Mormon Studies professionalized particularly after the 1960s.

Index Medicus
Index Medicus

Author:

Publisher:

Published: 2004

Total Pages: 1666

ISBN-13:

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Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

The Inner Life of the Dying Person
The Inner Life of the Dying Person

Author: Allan Kellehear

Publisher: Columbia University Press

Published: 2014-06-03

Total Pages: 284

ISBN-13: 0231167857

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This unique book recounts the experience of facing one’s death solely from the dying person’s point of view rather than from the perspective of caregivers, survivors, or rescuers. Such unmediated access challenges assumptions about the emotional and spiritual dimensions of dying, showing readers that—along with suffering, loss, anger, sadness, and fear—we can also feel courage, love, hope, reminiscence, transcendence, transformation, and even happiness as we die. A work that is at once psychological, sociological, and philosophical, this book brings together testimonies of those dying from terminal illness, old age, sudden injury or trauma, acts of war, and the consequences of natural disasters and terrorism. It also includes statements from individuals who are on death row, in death camps, or planning suicide. Each form of dying addressed highlights an important set of emotions and narratives that often eclipses stereotypical renderings of dying and reflects the numerous contexts in which this journey can occur outside of hospitals, nursing homes, and hospices. Chapters focus on common emotional themes linked to dying, expanding and challenging them through first-person accounts and analyses of relevant academic and clinical literature in psycho-oncology, palliative care, gerontology, military history, anthropology, sociology, cultural and religious studies, poetry, and fiction. The result is an all-encompassing investigation into an experience that will eventually include us all and is more surprising and profound than anyone can imagine.

Research Studies on Educating for Diversity and Social Justice
Research Studies on Educating for Diversity and Social Justice

Author: Ashraf Esmail

Publisher: Rowman & Littlefield

Published: 2018-08-24

Total Pages: 238

ISBN-13: 1475838387

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In the 21st century, issues around diversity and social justice have become popular buzz words in the educational discourse. This volume moves beyond “popular buzz” to critically explore issues of diversity and social justice through research studies that capture the complexity of educating in the 21st century. Drawing from a wide range of topics such as race, gender, sexual orientation, social class, language, parental involvement and special needs along with other issues; this volume pushes the boundaries of exploring diversity and social justice through the lens of intersectionality. It will be helpful for scholars and practitioners seeking to transform the educational experiences of historically underserved students.

Performing Feeling in Cultures of Memory
Performing Feeling in Cultures of Memory

Author: B. Trezise

Publisher: Springer

Published: 2014-06-27

Total Pages: 257

ISBN-13: 1137336226

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Performing Feeling in Cultures of Memory brings memory studies into conversation with a focus on feelings as cultural actors. It charts a series of memory sites that range from canonical museums and memorials, to practices enabled by the virtual terrain of Second Life, popular 'trauma TV' programs and radical theatre practice.